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Postorgasmic illness syndrome

Disease definition

Postorgasmic illness syndrome is a rare urogenital disease characterized by the appearance of flu-like symptoms (fever, extreme fatigue, myalgia, itchy burning eyes, nasal congestion/rhinorrhea), as well as mood changes, irritability and concentration, memory and attention difficulties, within a few minutes to a few hours after ejaculation. Symptoms disappear spontaneously 3-7 days after onset.

ORPHA:279947

Classification level: Disorder
  • Synonym(s):
    • POIS
  • Prevalence: <1 / 1 000 000
  • Inheritance: Not applicable 
  • Age of onset: Adolescent, Adult
  • ICD-10: F52.3
  • OMIM: -
  • UMLS: -
  • MeSH: -
  • GARD: 10809
  • MedDRA: -
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