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Plasmablastic lymphoma

Disease definition

A rare aggressive B-cell non-Hodgkin lymphoma characterized by neoplastic cells resembling B immunoblasts or plasmablasts with a CD20-negative plasmacytic phenotype. The tumor may occur in the oral cavity, the gastrointestinal tract, or other, predominantly extranodal, sites and is typically associated with immunodeficiency or -suppression. The tumor cells are EBV-positive in most cases. Patients often present with disseminated bone involvement. Paraproteinemia may also be detected. Prognosis is generally poor.

ORPHA:289666

Classification level: Disorder
  • Synonym(s):
    • PBL
  • Prevalence: -
  • Inheritance: -
  • Age of onset: -
  • ICD-10: C83.3
  • ICD-11: 2A81.2
  • OMIM: -
  • UMLS: C3472614
  • MeSH: D000069293
  • GARD: 12125
  • MedDRA: 10065039

  A summary on this disease is available in Español (2020) Français (2020) Nederlands (2020)

Additional information

Further information on this disease

Patient-centred resources for this disease

Research activities on this disease

Specialised Social Services

The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.