Orphanet: Chronic actinic dermatitis

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Chronic actinic dermatitis

Disease definition

Chronic actinic dermatitis (CAD) is an immunologically mediated photodermatosis usually observed in temperate climates and that typically develops in middle-aged to elderly males. CAD is characterized by eczematous and often lichenified pruritic patches and confluent plaques located predominantly on sun-exposed areas with notable sparing of eyelids, skin folds, and postauricular skin. It is often accompanied by multiple contact allergies and usually occurs in a background of either atopic, contact allergic, or seborrheic dermatitis, although it can occur de novo. Resolution of photosensitivity is reported in up to 50% of individuals after 15 years or more, with contact allergies persisting.


Classification level: Disorder
  • Synonym(s):
    • Actinic reticuloid
    • Chronic photosensitivity dermatitis
  • Prevalence: 1-5 / 10 000
  • Inheritance: Not applicable 
  • Age of onset: Adult
  • ICD-10: L57.8
  • OMIM: -
  • UMLS: C0282309  C1510437
  • MeSH: -
  • GARD: -
  • MedDRA: -
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