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X-linked parkinsonism-spasticity syndrome

Disease definition

A rare, genetic, neurological disorder characterized by parkinsonian features (including resting or action tremor, cogwheel rigidity, hypomimia and bradykinesia) associated with variably penetrant spasticity, hyperactive deep tendon reflexes and Babinski sign.

ORPHA:363654

Classification level: Disorder
  • Synonym(s):
    • XPDS
  • Prevalence: <1 / 1 000 000
  • Inheritance: X-linked recessive 
  • Age of onset: Adolescent, Adult
  • ICD-10: G20
  • OMIM: 300911
  • UMLS: C3806722
  • MeSH: -
  • GARD: -
  • MedDRA: -

  A summary on this disease is available in Español (2018) Français (2018) Italiano (2018) Nederlands (2018) Polski ()

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