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Hereditary late-onset Parkinson disease

Disease definition

Hereditary late-onset Parkinson disease (LOPD) is a form of Parkinson disease (PD), characterized by an age of onset of more than 50 years, tremor at rest, gait complaints and falls, bradykinesia, rigidity and painful cramps. Patients usually present a low risk of developing non motor symptoms, dystonia, dyskinesia and levodopa-induced dyskinesia (LID).


Classification level: Disorder
  • Synonym(s):
    • Autosomal dominant late-onset Parkinson disease
    • LOPD
  • Prevalence: Unknown
  • Inheritance: Autosomal dominant 
  • Age of onset: Adult, Elderly
  • ICD-10: G20
  • OMIM: 168601  605543  607060  607688  614203  614251  616361
  • UMLS: C4274355
  • MeSH: -
  • GARD: -
  • MedDRA: -

Detailed information

Disease review articles

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The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.