Orphanet: Dysbetalipoproteinemia

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Disease definition

A rare combined hyperlipidemia (HLP type 3) characterized by high levels of cholesterol and triglycerides, transported by intermediate density lipoproteins (IDLs), and a high risk of progressive atherosclerosis and premature cardiovascular disease.


Classification level: Disorder
  • Synonym(s):
    • Broad-beta disease
    • Familial dyslipidemia type 3
    • HLP type 3
    • Hyperlipidemia type 3
    • Hyperlipoproteinemia type 3
    • Remnant hyperlipoproteinemia
  • Prevalence: 1-5 / 10 000
  • Inheritance: Multigenic/multifactorial or Autosomal dominant 
  • Age of onset: Adolescent, Adult, Elderly, Childhood
  • ICD-10: E78.2
  • OMIM: 617347
  • UMLS: C0020479
  • MeSH: D006952
  • GARD: 6703
  • MedDRA: 10060751

Detailed information


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