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Malan overgrowth syndrome

Disease definition

A rare multisystemic genetic disorder characterized by a characteristic facial features with macrocephaly, overgrowth in infancy, intellectual disability and behavioral problems including anxieties and aggressiveness.


Classification level: Disorder
  • Synonym(s):
    • Sotos syndrome 2
  • Prevalence: <1 / 1 000 000
  • Inheritance: Autosomal dominant or Unknown 
  • Age of onset: Infancy
  • ICD-10: Q87.3
  • ICD-11: LD2C
  • OMIM: 614753
  • UMLS: C3553660
  • MeSH: -
  • GARD: -
  • MedDRA: -
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