Search for a rare disease
Other search option(s)
NUT midline carcinoma
Disease definition
A rare tumor characterized by a rapidly growing mass usually arising along the midline, defined by the presence of NUTM1 rearrangements. Histopathological examination shows a poorly differentiated carcinoma, often with evidence of squamous differentiation. Patients present with unspecific signs and symptoms due to mass effect, depending on the location. Extensive local invasion of adjacent structures, lymph node involvement, and distant metastatic disease are often present at the time of diagnosis. Prognosis is generally poor.
ORPHA:443167
Classification level: Disorder- Synonym(s):
- NMC
- Prevalence: -
- Inheritance: Not applicable
- Age of onset: Childhood, Adolescent, Adult, Elderly
- ICD-10: C80.9
- OMIM: -
- UMLS: C1707291
- MeSH: -
- GARD: -
- MedDRA: 10078295
A summary on this disease is available in Español (2020) Français (2020) Nederlands (2020)
Additional information
Further information on this disease
Patient-centred resources for this disease
Research activities on this disease
Specialised Social Services
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.