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Aquagenic palmoplantar keratoderma

Disease definition

A rare skin disease characterized by transient wrinkling of the skin, edema, formation of whitish papules, pruritus, burning sensation, or pain, on the palms and/or soles in response to contact with water. Duration of exposure and water temperature affect the rate of development and intensity of the lesions. The condition is more common in females than in males and frequently occurs in patients with cystic fibrosis.

ORPHA:498359

Classification level: Disorder
  • Synonym(s):
    • Aquagenic keratoderma
    • Aquagenic syringeal acrokeratoderma
    • Aquagenic wrinkling of the palms
    • Transient reactive papulotranslucent acrokeratoderma
  • Prevalence: Unknown
  • Inheritance: -
  • Age of onset: Adolescent, Adult, Infancy, Childhood
  • ICD-10: L85.1
  • ICD-11: EK5Y
  • OMIM: -
  • UMLS: C4087301
  • MeSH: -
  • GARD: -
  • MedDRA: -

  A summary on this disease is available in Español (2020) Français (2020) Nederlands (2020)

Detailed information

Guidelines

ERN produced/endorsed by ERN(s)   FSMR produced/endorsed by FSMR(s)

Additional information

Further information on this disease

Patient-centred resources for this disease

Research activities on this disease

Specialised Social Services

The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.