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Necrobiosis lipoidica
Disease definition
A rare skin disease characterized by enlarging, annular plaques with red-brown edges and atrophic, yellow-brown, telangiectatic centers. The lesions are commonly asymptomatic, but affected skin areas may be fragile, and painful ulcerations develop in many cases. In rare cases, development of squamous cell carcinoma within longstanding lesions has been reported. The lower legs, especially the shins, are the most frequently involved site. The condition is often associated with diabetes mellitus.
ORPHA:542592
Classification level: Disorder- Synonym(s):
- Oppenheim-Urbach disease
- Prevalence: Unknown
- Inheritance: -
- Age of onset: Childhood, Adolescent, Adult, Elderly
- ICD-10: L92.1
- ICD-11: EE80.1
- OMIM: -
- UMLS: -
- MeSH: -
- GARD: -
- MedDRA: -
A summary on this disease is available in Español (2020) Français (2020) Nederlands (2020)
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