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Osteochondrosis of the metatarsal bone
Disease definition
A rare bone disease characterized by avascular necrosis of a metatarsal head, most commonly involving the second, but also the third or fourth, metatarsal. Patients may present with pain on weight-bearing, swelling, and tenderness. Radiological features include widening of the metatarsophalangeal joint space and flattening of the affected metatarsal head, at later stages metatarsal head sclerosis, cortical thickening, and intra-articular loose bodies. The condition can be bilateral in some cases and shows a significant predilection for females in the second or third decade of life.
ORPHA:564003
Classification level: Disorder- Synonym(s):
- Avascular necrosis of the metatarsal bone
- Freiberg disease
- Freiberg infraction
- Prevalence: Unknown
- Inheritance: -
- Age of onset: Adolescent, Adult
- ICD-10: M92.7
- OMIM: -
- UMLS: -
- MeSH: -
- GARD: -
- MedDRA: -
A summary on this disease is available in Español (2020) Français (2020) Nederlands (2020)
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