Orphanet: Classic hairy cell leukemia

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Classic hairy cell leukemia

Disease definition

Hairy cell leukemia (HCL) is a rare type of leukemia in which abnormal B-lymphocytes are present in the bone marrow, spleen and peripheral blood. It is a slowly progressive chronic lymphocytic leukemia (CLL). The name comes from the abnormally shaped lymphocytes with hair-like projections.


Classification level: Disorder
  • Synonym(s):
    • HCL-C
    • Leukemic reticuloendotheliosis
  • Prevalence: 1-9 / 100 000
  • Inheritance: -
  • Age of onset: Adult
  • ICD-10: C91.4
  • OMIM: -
  • UMLS: C0023443
  • MeSH: D007943
  • GARD: 6560
  • MedDRA: 10019053

Detailed information

Article for general public


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