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Tolosa-Hunt syndrome

Disease definition

Tolosa-Hunt syndrome is an ophthalmoplegic syndrome, affecting all age groups, characterized by acute attacks (lasting a few days to a few weeks) of periorbital pain, ipsilateral ocular motor nerve palsies, ptosis, disordered eye movements and blurred vision usually caused by a non-specific inflammatory process in the cavernous sinus and superior orbital fissure. It has an unpredicatable course with spontaneous remission occurring in some and recurrence of attacks in others.


Classification level: Disorder
  • Synonym(s):
    • Painful ophthalmoplegia
  • Prevalence: -
  • Inheritance: -
  • Age of onset: All ages
  • ICD-10: H49.8
  • OMIM: -
  • UMLS: C0040381
  • MeSH: C531833  D020333
  • GARD: 7777
  • MedDRA: 10051526
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