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Pruritic urticarial papules and plaques of pregnancy

Disease definition

A rare skin disease characterized by urticarial papules and plaques with severe pruritus mainly on the abdomen, buttocks, and proximal thighs. The condition usually develops during the third trimester of the first pregnancy, although presentation in the postpartum period, which may also feature other types of skin lesions, has been described in some cases. The symptoms generally resolve within few weeks.

ORPHA:64745

Classification level: Disorder
  • Synonym(s):
    • PUPPP
    • Polymorphic eruption of pregnancy
  • Prevalence: Unknown
  • Inheritance: -
  • Age of onset: Adult, Adolescent
  • ICD-10: O26.8
  • ICD-11: JA65.12
  • OMIM: 178995
  • UMLS: C0269680
  • MeSH: C535817
  • GARD: 9635
  • MedDRA: 10066100
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