Orphanet: Hereditary motor and sensory neuropathy type 5
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Hereditary motor and sensory neuropathy type 5

Disease definition

Hereditary motor and sensory neuropathy type 5 is a rare axonal hereditary motor and sensory neuropathy characterized by slowly progressive distal muscle weakness and atrophy with or without sensory loss resulting in difficulty in walking, foot drop and pes cavus, that may be associated with pyramidal signs (extensor plantar responses, mild increase in tone, brisk tendon reflexes), muscle cramps, pain and spasticity.

ORPHA:64751

Classification level: Disorder
  • Synonym(s):
    • Charcot-Marie-Tooth disease-pyramidal features syndrome
    • HMSN 5
    • HMSN V
    • Hereditary motor and sensory neuropathy type V
  • Prevalence: -
  • Inheritance: -
  • Age of onset: Adult
  • ICD-10: G60.0
  • OMIM: 600361
  • UMLS: -
  • MeSH: -
  • GARD: 9208
  • MedDRA: -

  A summary on this disease is available in Español (2018) Italiano (2018) Nederlands (2018) Polski ()

Detailed information

Guidelines

ERN : produced/endorsed by ERN(s)
FSMR : produced/endorsed by FSMR(s)

Additional information

Further information on this disease

Patient-centred resources for this disease

Research activities on this disease

Specialised Social Services

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