Orphanet: Progressive supranuclear palsy

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Progressive supranuclear palsy

Disease definition

A rare late-onset neurodegenerative disease characterized by supranuclear gaze palsy, postural instability, progressive rigidity, and mild dementia.


Classification level: Disorder
  • Synonym(s):
    • PSP syndrome
  • Prevalence: 1-9 / 100 000
  • Inheritance: Not applicable 
  • Age of onset: Adult
  • ICD-10: G23.1
  • OMIM: 260540  601104  609454  610898
  • UMLS: C0038868
  • MeSH: D013494
  • GARD: 7471
  • MedDRA: 10036813

Detailed information


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