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Acute ackee fruit intoxication

Disease definition

A rare disease caused by the ingestion of unripe Blighia sapida fruits. It is a serious intoxication that is frequent in certain countries in the Caribbean and Western Africa. In contrast, it is rare in France and other Western countries. Intoxication leads to toxic hypoglycaemia and inhibition of neoglucogenesis. The hypoglycaemia is caused by the effect of hypoglycin A, which is found in the arils.

ORPHA:73423

Classification level: Disorder
  • Synonym(s):
    • Acute intoxication by Blighia sapida
    • Jamaican vomiting sickness
    • Jamaican vomiting syndrome
  • Prevalence: Unknown
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: T62.2
  • OMIM: -
  • UMLS: C0274888
  • MeSH: -
  • GARD: 9299
  • MedDRA: -
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