x

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.

Attention

Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Loeffler endocarditis

Disease definition

Loeffler's endocarditis is a rare restrictive cardiomyopathy (see this term) characterized by hypereosinophilia and fibrous thickening of the endocardium, with usually large thrombi against the ventricle walls, that can lead to cardiovascular complications such as heart failure and thromboembolism. It manifests with symptoms like edema, fatigue and shortness of breath. It is usually secondary to eosinophil-associated tissue damage and is associated with idiopathic hypereosinophilic syndrome, chronic eosinophilic leukemia (see these terms), carcinoma, or lymphoma.

ORPHA:75566

  • Synonym(s):
    • Eosinophilic endocarditis
  • Prevalence: Unknown
  • Inheritance: -
  • Age of onset: Adolescent, Childhood, Adult
  • ICD-10: I42.3
  • OMIM: -
  • UMLS: C0206143
  • MeSH: -
  • GARD: -
  • MedDRA: 10052841

Detailed information

Professionals

Additional information

Specialised Social Services

The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.