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Morvan syndrome

Disease definition

Morvan syndrome is a rare, life-threatening, acquired neurologic disease characterized by neuromyotonia, dysautonomia and encephalopathy with severe insomnia. Signs involving central (e.g. hallucinations, confusion, amnesia, myoclonus), autonomic (e.g. variations in blood pressure, hyperhidrosis) and peripheral (e.g. painful cramps, myokymia) hyperactivity, as well as systemic manifestations (such as weight loss, pruritus, fever), are reported. Thymoma is present in some cases.

ORPHA:83467

Classification level: Disorder
  • Synonym(s):
    • Limbic encephalitis-neuromyotonia-hyperhidrosis-polyneuropathy syndrome
    • Morvan fibrillary chorea
  • Prevalence: <1 / 1 000 000
  • Inheritance: -
  • Age of onset: Adult
  • ICD-10: G60.8
  • OMIM: -
  • UMLS: C0751540  C3854373
  • MeSH: -
  • GARD: 9766
  • MedDRA: -

Additional information

Further information on this disease

Patient-centred resources for this disease

Research activities on this disease

Specialised Social Services

The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.