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Fetal and neonatal alloimmune thrombocytopenia

Disease definition

A rare hematological disease characterized by maternal alloimmunisation against fetal platelet antigens that are inherited from the father and different from those present in the mother, and usually presents as a severe isolated thrombocytopenia in otherwise healthy newborns.


Classification level: Disorder
  • Synonym(s):
    • FNAIT
    • NAIT
  • Prevalence: 1-5 / 10 000
  • Inheritance: Not applicable 
  • Age of onset: Antenatal, Neonatal
  • ICD-10: P61.0
  • ICD-11: 3B64.00
  • OMIM: -
  • UMLS: C3854603
  • MeSH: -
  • GARD: 2295
  • MedDRA: -

Detailed information

Disease review articles

ERN : produced/endorsed by ERN(s)
FSMR : produced/endorsed by FSMR(s)
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.