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Plasmacytoma
Disease definition
Plasmacytoma is a localized mass of neoplastic monoclonal plasma cells that represents approximately 5% of all plasma cell neoplasms. There are two separate entities: primary plasmacytoma of the bone and extramedullary plasmacytoma of the soft tissues. Of the extramedullary plasmacytomas, 80% occur in the head and neck, usually in the upper respiratory tract. The median age at diagnosis is 50 years and the male to female ratio is 3:1. Long-term survival is possible following local radiotherapy, particularly for soft tissue presentations.
ORPHA:86855
Classification level: Disorder- Synonym(s):
- Solitary plasmacytoma
- Prevalence: Unknown
- Inheritance: Not applicable
- Age of onset: Adult
- ICD-10: C90.2 C90.3
- OMIM: -
- UMLS: C0032131
- MeSH: D010954
- GARD: -
- MedDRA: 10035484
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