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Superior limbic keratoconjunctivitis

Disease definition

A rare disorder of the anterior segment of the eye characterized by unilateral or bilateral, chronic and recurrent inflammation affecting the upper tarsal and bulbar conjunctiva, as well as the superior limbus, manifesting as a papillary reaction on the upper tarsal conjunctiva, thickening and folding of redundant superior bulbar conjunctiva, and superficial punctate epithelial keratitis with or without filament formation near the superior corneal limbus. Middle-aged women are most commonly affected and present with foreign body sensation, frequent blinking, burning sensation, and pruritus, among others.

ORPHA:88633

Classification level: Disorder
  • Synonym(s):
    • SLK
    • Theodore superior limbic keratoconjunctivitis
    • Theodore syndrome
  • Prevalence: -
  • Inheritance: -
  • Age of onset: -
  • ICD-10: H16.2
  • OMIM: -
  • UMLS: C0339229
  • MeSH: -
  • GARD: 10940
  • MedDRA: -
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