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Cushing syndrome due to ectopic ACTH secretion

Disease definition

Cushing syndrome due to ectopic (adrenocorticotropic hormone) ACTH secretion (EAS) is a form of ACTH-dependent Cushing syndrome (see this term) caused by excess secretion of ACTH by a benign or, more often, malignant non-pituitary tumor.


Classification level: Disorder
  • Synonym(s):
    • Adrenocorticotropic hormone secretion syndrome
    • Ectopic ACTH secreting tumor
    • Ectopic Cushing syndrome
    • Occult ectopic ACTH secretion
    • Paraneoplastic Cushing syndrome
  • Prevalence: Unknown
  • Inheritance: Not applicable 
  • Age of onset: Adult, Elderly
  • ICD-10: E24.3
  • ICD-11: 5A70.1
  • OMIM: -
  • UMLS: C0001231
  • MeSH: -
  • GARD: -
  • MedDRA: -

Detailed information

General public


Disease review articles

Clinical Outcome Assessment (COA)

  • Patient-Centered Outcome Measures (PCOMs)
  • English (2023) - PROQOLIDTM
ERN produced/endorsed by ERN(s)   FSMR produced/endorsed by FSMR(s)
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