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National clinical trial(s)

AUSTRALIA
Victoria
ADDRESS: NOT PROVIDED - AU

COMPASS: A Phase 2/3, Multicenter, Double-Blind, Randomized Study to Determine the Efficacy and Safety of DNL310 vs Idursulfase in Pediatric Participants With Neuronopathic or Non-Neuronopathic Mucopolysaccharidosis Type II -AU
Institution: Information not provided - AU

BELGIUM
ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

COMPASS: A Phase 2/3, Multicenter, Double-Blind, Randomized Study to Determine the Efficacy and Safety of DNL310 vs Idursulfase in Pediatric Participants With Neuronopathic or Non-Neuronopathic Mucopolysaccharidosis Type II - BE
Cliniques universitaires Saint-Luc - UCLouvain
Cliniques Universitaires Saint-Luc

FRANCE
HAUTS-DE-FRANCE
ADDRESS: NOT PROVIDED - FR

COMPASS: A Phase 2/3, Multicenter, Double-Blind, Randomized Study to Determine the Efficacy and Safety of DNL310 vs Idursulfase in Pediatric Participants With Neuronopathic or Non-Neuronopathic Mucopolysaccharidosis Type II -FR
Institution: Information not provided - FR

GERMANY
Berlin
ADDRESS: NOT PROVIDED - DE

COMPASS: A Phase 2/3, Multicenter, Double-Blind, Randomized Study to Determine the Efficacy and Safety of DNL310 vs Idursulfase in Pediatric Participants With Neuronopathic or Non-Neuronopathic Mucopolysaccharidosis Type II - DE
Institution: Information not provided - DE

GERMANY
Hamburg
HAMBURG

A Phase III study of JR-141 in Mucopolysaccharidosis type II (Hunter Syndrome) patients - DE
UKE - Universitätsklinikum Hamburg-Eppendorf

GERMANY
Rheinland-Pfalz
MAINZ


A Long-Term, Open-Label, Multicenter, Phase IV Study to Assess Longitudinal Changes on Height and Weight in Patients With Mucopolysaccharidosis type 2 Who Are Receiving Elaprase and Started Treatment With Elaprase at <6 Years of Age - DE
Universitätsmedizin Mainz
Villa Metabolica - Schwerpunktbereich angeborene Stoffwechselerkrankungen

SPAIN
Cataluña
ESPLUGUES DE LLOBREGAT

A Phase III study of JR-141 in Mucopolysaccharidosis type II (Hunter Syndrome) patients -ES
Hospital Sant Joan de Déu Barcelona

SPAIN
Madrid
ADDRESS: NOT PROVIDED - ES

COMPASS: A Phase 2/3, Multicenter, Double-Blind, Randomized Study to Determine the Efficacy and Safety of DNL310 vs Idursulfase in Pediatric Participants With Neuronopathic or Non-Neuronopathic Mucopolysaccharidosis Type II -ES
Institution: Information not provided - ES

SPAIN
Madrid
MADRID

An Open Label Extension of Study HGT-HIT-094 Evaluating Long Term Safety and Clinical Outcomes of Intrathecal Idursulfase Administered in Conjunction with Elaprase® in Patients with Hunter Syndrome and Cognitive Impairment -ES
Hospital Infantil Universitario Niño Jesús
Servicio de Neurología

SWEDEN
Region Stockholm
ADDRESS: NOT PROVIDED - SE

COMPASS: A Phase 2/3, Multicenter, Double-Blind, Randomized Study to Determine the Efficacy and Safety of DNL310 vs Idursulfase in Pediatric Participants With Neuronopathic or Non-Neuronopathic Mucopolysaccharidosis Type II - SE
Institution: Information not provided - SE

UNITED KINGDOM
Greater London
ADDRESS: NOT PROVIDED - GB

COMPASS: A Phase 2/3, Multicenter, Double-Blind, Randomized Study to Determine the Efficacy and Safety of DNL310 vs Idursulfase in Pediatric Participants With Neuronopathic or Non-Neuronopathic Mucopolysaccharidosis Type II -GB
Institution: Information not provided - GB

UNITED KINGDOM
West Midlands
BIRMINGHAM

MCRN174 (HGT-HIT-046) : An Open-Label Extension of Study HGT-HIT-045 Evaluating Long-Term Safety and Clinical Outcomes of Intrathecal Idursulfase-IT Administered in Conjunction with Intravenous Elaprase in Pediatric Patients with Hunter Syndrome and Cognitive Impairment (Phase I/II)
Birmingham Children's Hospital NHS Foundation Trust
Birmingham Children's Hospital

UNITED KINGDOM
Greater Manchester
MANCHESTER

The efficacy and mechanism of trientine in patients with hypertrophic cardiomyopathy
Wythenshawe Hospital
Cardiology
Multinational clinical trial(s)

UNITED STATES
Washington
ADDRESS: NOT PROVIDED - US
A Controlled, Randomized, Two-arm, Open-label, Assessor-blinded, Multicenter Study of Intrathecal Idursulfase-IT Administered in Conjunction with Elaprase® in Pediatric Patients with Hunter Syndrome and Early Cognitive Impairment (Phase II-III)
Institution: Information not provided - US

UNITED STATES
Washington
ADDRESS: NOT PROVIDED - US
A Phase 1 Safety and Dose-Finding Study of a Human Insulin Receptor Monoclonal Antibody-Human Iduronate 2-Sulfatase (IDS) Fusion Protein, AGT-182 in Adult Patients With Mucopolysaccharidosis II (MPS II, Hunter Syndrome)
Institution: Information not provided - US

UNITED STATES
Washington
ADDRESS: NOT PROVIDED - US
COMPASS: A Phase 2/3, Multicenter, Double-Blind, Randomized Study to Determine the Efficacy and Safety of DNL310 vs Idursulfase in Pediatric Participants With Neuronopathic or Non-Neuronopathic Mucopolysaccharidosis Type II.
Institution: Information not provided - US

UNITED KINGDOM
Greater Manchester
RADCLIFFE