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National clinical trial(s)

AUSTRIA
WIEN
WIEN

A Multicenter Phase 1, Open-Label Study of DCC-2618 to Assess Safety, Tolerability, and Pharmacokinetics in Patients With Advanced Malignancies - AT
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Hämatologie und Hämostaseologie

AUSTRIA
WIEN
ADDRESS: NOT PROVIDED - AT

PATHFINDER: An Open-label, Single Arm, Phase 2 Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, in Patients With Advanced Systemic Mastocytosis - AT
Institution: Information not provided - AT

BELGIUM
ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS
STEP: Sorafenib Long Term Extension Program - BE
Cliniques universitaires Saint-Luc - UCLouvain
Pneumologie_Oncologie thoracique

GERMANY
Baden-Württemberg
MANNHEIM

CPKC412D2201 - A single arm, phase II, open-label study to determine the efficacy of 100 mg twice daily of Midostaurin administered to patients with Aggressive Systemic Mastocytosis or Mast Cell Leukemia +/- an associated hematological clonal non-mast cell lineage disease - DE
Universitätsmedizin Mannheim
III. Medizinische Klinik

GERMANY
Berlin
BERLIN
Phase 3 Study to Compare Oral Masitinib to Placebo in Treatment of Patients With Smouldering or Indolent Severe Systemic Mastocytosis, Unresponsive to Optimal Symptomatic Treatment -DE
Charité - Universitätsmedizin Berlin

ITALY
LAZIO
ROMA
An Open-Label, Single-Arm, Phase 1/2 Study Evaluating the Safety and Efficacy of Ponatinib for the Treatment of Recurrent or Refractory Leukemias or Solid Tumors in Pediatric Participants - IT
IRCCS Ospedale Pediatrico Bambino Gesů - SEDE GIANICOLO
U.O. di Oncoematologia

NETHERLANDS
Zuid-Holland
ROTTERDAM

COMPARE 60/80 HBR: Comparison of the Supraflex Cruz 60 Micron Stent Strut Versus the Ultimaster Tansei 80 Micron Stent Strut in High Bleeding Risk PCI Population
Maasstad Ziekenhuis
Polikliniek Cardiologie

SPAIN
Castilla - La Mancha
TOLEDO
PATHFINDER: An Open-label, Single Arm, Phase 2 Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, in Patients With Advanced Systemic Mastocytosis - ES
Hospital Virgen del Valle
Instituto de Estudios de Mastocitosis de Castilla La Mancha

SPAIN
Castilla - La Mancha
TOLEDO

PIONEER: A 3-Part, Randomized, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate Safety and Efficacy of Avapritinib (BLU-285), a Selective KIT Mutation-Targeted Tyrosine Kinase Inhibitor, in Indolent and Smoldering Systemic Mastocytosis with Symptoms Inadequately Controlled with Standard Therapy - ES
Hospital Virgen del Valle
Instituto de Estudios de Mastocitosis de Castilla La Mancha

SPAIN
Madrid
ADDRESS: NOT PROVIDED - ES

A 24-week with possible extension, prospective, multicenter, randomized, double blind, placebo-controlled, 2-parallel group with a randomization 1:1, phase III study to compare efficacy and safety of oral masitinib to placebo in treatment of patients with Smouldering or Indolent Severe Systemic mastocytosis with handicap [...] - ES
Institution: Information not provided - ES

SPAIN
Madrid
ADDRESS: NOT PROVIDED - ES

HARBOR: A Randomized, Double-Blind, Placebo-Controlled Phase 2/3 Study of BLU-263 in Indolent Systemic Mastocytosis - ES
Institution: Information not provided - ES

SPAIN
Madrid
MADRID

A Phase 2 Open-Label, Multicenter Clinical Study of the Safety, Efficacy, Pharmacokinetic, and Pharmacodynamic Profiles of CGT9486 as a Single Agent in Patients With Advanced Systemic Mastocytosis - ES
Hospital Universitario Ramón y Cajal
Unidad de Trasplantes
Multinational clinical trial(s)

SPAIN
Madrid
COLMENAR VIEJO
APL-A-005-02: Phase I - II clinical and pharmacokinetic study of Aplidin (APL) as a 3-hour intravenous infusion every 2 weeks, in children with refractory or relapsed malignant tumours and leukemia (coordination)
PharmaMar S.A.
Pharma Mar S.A.

SWITZERLAND
Suisse Alémanique
BASEL

UNITED STATES
Kansas
LAWRENCE