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National clinical trial(s)

Hessen
FRANKFURT AM MAIN

OlaReDo: Efficacy of Olaratumab and Rechallenge With Doxorubicin in Anthracycline Pretreated, Advanced Soft Tissue Sarcoma Patients. An Exploratory Phase-II Study
Krankenhaus Nordwest GmbH
Institut für Klinische Krebsforschung IKF GmbH

County Dublin
DUBLIN

European Paediatric Soft Tissue Sarcoma Study Group protocol for Localized Non-Rhabdomyosarcoma Soft Tissue Sarcomas 2005 (phase III) - IE
Children's Health Ireland @ Crumlin
Department of Paediatric Haematology and Oncology

Suisse Romande
ADDRESS: NOT PROVIDED - CH
ANNOUNCE 2: A Phase 1b (Open-Label) / Phase 2 (Randomized,Double-Blinded) Study Evaluating Gemcitabine andDocetaxel With or Without Olaratumab in the Treatment ofAdvanced Soft Tissue Sarcoma -GB
Institution: Information not provided - CH

WIEN
WIEN
ANNOUNCE: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Doxorubicin Plus Olaratumab Versus Doxorubicin Plus Placebo in Patients With Advanced or Metastatic Soft Tissue Sarcoma - AT
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Onkologie

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

A phase I/IIa study of intra-tumoral BT-001 (TG6030) administered alone and in combination with pembrolizumab in patients with cutaneous or, subcutaneous lesions or easily injectable lymph nodes of metastatic/advanced solid tumors - BE
Cliniques universitaires Saint-Luc - UCLouvain
Service d'oncologie médicale

VLAAMS BRABANT
LEUVEN
An Open-Label, Multicenter, Phase 1a/1b Study of Olaratumab (LY3012207) Plus Pembrolizumab (MK3475) in Patients With Unresectable Locally Advanced or Metastatic Soft Tissue Sarcoma (STS) Who Have Failed Standard Treatments - BE
UZ Leuven - Campus Gasthuisberg
General medical oncology/Dienst Algemene Medische Oncologie

Québec
ADDRESS: NOT PROVIDED - CA
A Phase II Study of Cixutumumab (IMC-A12) in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors
Institution: Information not provided - CA

AUVERGNE-RHONE-ALPES
LYON
Multicenter phase I/II study of continuous dosing of Sunitinib in non-GIST sarcomas with concomitant radiation therapy.
CLCC Léon Bérard
Radiothérapie

HAUTS-DE-FRANCE
ADDRESS: NOT PROVIDED - FR

Combining Epigenetic And Immune Therapy to Beat Cancer. CAIRE Study
Institution: Information not provided - FR

HAUTS-DE-FRANCE
ADDRESS: NOT PROVIDED - FR

A Phase I/IIa Study of Intra-tumoral BT-001 (TG6030) Administered Alone and in Combination With Pembrolizumab in Patients With Cutaneous or, Subcutaneous Lesions or Easily Injectable Lymph Nodes of Metastatic/Advanced Solid Tumors.-FR
Institution: Information not provided - FR

HAUTS-DE-FRANCE
ADDRESS: NOT PROVIDED - FR

Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Grade 1 or 2 Soft Tissue Sarcoma
Institution: Information not provided - FR

NOUVELLE AQUITAINE
BORDEAUX

RADIOSARP : A Phase Ib Study of Olaparib With Concomitant Radiotherapy in Locally Advanced/Unresectable Soft-tissue Sarcoma
CLCC Institut Bergonié
Département d'oncologie médicale - Sarcomes

NOUVELLE AQUITAINE
BORDEAUX

TRAMUNE : Trabectedin Combined With Durvalumab (MEDI4736) in Patients With Advanced Pretreated Soft-tissue Sarcomas and Ovarian Carcinomas : A Phase Ib Study
CLCC Institut Bergonié
Département d'oncologie médicale - Sarcomes

NOUVELLE AQUITAINE
BORDEAUX

TARMIC : Targeting Microenvironment and Cellular Immunity in Sarcomas Weekly trabectedin combined with Metronomic Cyclophosphamide in Patients with Advanced Pretreated Soft-tissue Sarcomas. A Phase I/II study from the French Sarcoma Group
CLCC Institut Bergonié
Département d'oncologie médicale - Sarcomes

NOUVELLE AQUITAINE
BORDEAUX

TRUST Study: Bintrafusp Alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma.
CLCC Institut Bergonié
Département d'oncologie médicale - Sarcomes

Baden-Württemberg
HEIDELBERG

Retro-Ion: Neoadjuvant Irradiation of Retroperitoneal Soft Tissue Sarcoma With Ions Retro-Ion Prospektive Randomisierte Phase-II-Studie
Neurologische Universitätsklinik Heidelberg
Klinik für Radioonkologie und Strahlentherapie

Nordrhein-Westfalen
MÜNSTER

FLASH: A Randomized Study to Investigate the Efficacy and Safety of the Tumor-targeting Human Antibody-cytokine Fusion Protein L19TNF in Previously Treated Patients With Advanced Stage or Metastatic Soft-tissue Sarcoma
Universitätsklinikum Münster
Medizinische Klinik und Poliklinik A

EMILIA ROMAGNA
MELDOLA

A Phase II Study on Adjuvant Vaccination With Dendritic Cells Loaded With Autologous Tumor Homogenate in Resected Stage IV Rare Cancers: Head&Neck (H&N), Neuroendocrine Tumors (NET) and Soft Tissue Sarcoma (STS)
IRST - Istituto Scientifico Romagnolo per lo studio e la cura dei Tumori
Dipartimento di Oncologia ed Ematologia Clinica e Sperimentale

LAZIO
ROMA
A Randomized Phase II Trial Comparing the Activity of trabectedIn vs Gemcitabine in Patients With Metastatic or Locally Advanced Leiomyosarcoma Pretreated With Conventional Chemotherapy
Policlinico Universitario Campus Bio-Medico
U.O.C. Oncologia Medica

Noord-Holland
AMSTERDAM
The Drug Rediscovery Protocol (DRUP trial): A Dutch National Study on behalf of the Center for Personalized Cancer Treatment (CPCT) to Facilitate Patient Access to Commercially Available, Targeted Anti-cancer Drugs to determine the Potential Efficacy in Treatment of Advanced Cancers with a Known Molecular Profile (Phase II)
Het Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis
Afdeling Maag-Darm-Leveroncologie

Comunidad Valenciana
VALENCIA
ANNOUNCE: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Doxorubicin plus Olaratumab versus Doxorubicin plus Placebo in Patients with Advanced or Metastatic Soft Tissue Sarcoma -ES
Hospital Universitario y Politécnico La Fe
Servicio de Oncología Médica

Madrid
ADDRESS: NOT PROVIDED - ES

FLASH: A randomized study to investigate the efficacy and safety of the tumor-targeting human antibody-cytokine fusion protein L19TNF in previously treated patients with advanced stage or metastatic soft-tissue sarcoma -ES
Institution: Information not provided - ES

Madrid
ADDRESS: NOT PROVIDED - ES


TOLERANCE: a 3 arm randomized study on health-related quality of life of elderly patients with advanced soft tissue sarcoma undergoing doxorubicin every three weeks or doxorubicin weekly or cyclophosphamide plus prednisolone treatment -ES
Institution: Information not provided - ES

Washington
ADDRESS: NOT PROVIDED - US


Pembrolizumab and Doxorubicin Hydrochloride in Treating Patients With Sarcoma That is Metastatic or Cannot Be Removed by Surgery
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US


Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US


Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US


MDM2 Inhibitor AMG-232 and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma
Institution: Information not provided - US

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS
STEP: Sorafenib Long Term Extension Program - BE
Cliniques universitaires Saint-Luc - UCLouvain
Pneumologie_Oncologie thoracique

EMILIA ROMAGNA
ADDRESS: NOT PROVIDED - IT

A Randomized, Open-label, Safety and Efficacy Study of Ibrutinib in Pediatric and Young Adult Patients With Relapsed or Refractory Mature B-cell Non-Hodgkin Lymphoma - IT
Institution: Information not provided - IT

LAZIO
ROMA
An Open-Label, Single-Arm, Phase 1/2 Study Evaluating the Safety and Efficacy of Ponatinib for the Treatment of Recurrent or Refractory Leukemias or Solid Tumors in Pediatric Participants - IT
IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO
U.O. di Oncoematologia

Washington
ADDRESS: NOT PROVIDED - US


Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
Institution: Information not provided - US
Multinational clinical trial(s)

Berlin
ADDRESS: NOT PROVIDED - DE
PazoQol: Quality of life in patients with non-adipocyte soft tissue sarcoma underpalliative chemotherapy or pazopanib - a randomized, controlled trial
Institution: Information not provided - DE

Cataluña
SANT QUINTÍ DE MEDIONA

Washington
ADDRESS: NOT PROVIDED - US
A Phase 1b Trial to Assess the Modulation of Biological Markers in Patients With Potentially Resectable Soft Tissue Sarcoma Treated With Olaratumab Monotherapy Followed by Olaratumab Plus Doxorubicin Combination Therapy
Institution: Information not provided - US

ARRONDISSEMENT BRUSSELS-CAPITAL
ADDRESS: NOT PROVIDED - BE
STRASS: A Phase III Randomized Study of Preoperative Radiotherapy Plus Surgery Versus Surgery Alone for Patients With Retroperitoneal Sarcoma (RPS)
Institution: Information not provided - BE

ARRONDISSEMENT BRUSSELS-CAPITAL
ADDRESS: NOT PROVIDED - BE
A Phase I/IIa Study of Intra-tumoral BT-001 (TG6030) Administered Alone and in Combination With Pembrolizumab in Patients With Cutaneous or, Subcutaneous Lesions or Easily Injectable Lymph Nodes of Metastatic/Advanced Solid Tumors.
Institution: Information not provided - BE

Berlin
ADDRESS: NOT PROVIDED - DE
Doxo: Phase II pharmacokinetic study to assess the age-dependency in the clearance of Doxorubicin in paediatric patients with Solid Tumours and Leukaemia
Institution: Information not provided - DE

EMILIA ROMAGNA
ADDRESS: NOT PROVIDED - IT
Localized High-Risk Soft Tissue Sarcomas Of The Extremities And Trunk Wall In Adults: An Integrating Approach Comprising Standard Vs Histotype-Tailored Neoadjuvant Chemotherapy
Institution: Information not provided - IT

Greater London
ADDRESS: NOT PROVIDED - GB
GeDDiS : A prospective randomised controlled phase III trial of gemcitabine and docetaxel compared with doxorubicin as first line treatment in previously untreated advanced unresectable or metastatic soft tissue sarcomas
Institution: Information not provided - GB

Kansas
LAWRENCE
A Multicenter Phase 1, Open-Label Study of DCC-2618 to Assess Safety, Tolerability, and Pharmacokinetics in Patients With Advanced Malignancies
Deciphera Pharmaceuticals, LLC.

Washington
ADDRESS: NOT PROVIDED - US
PICASSO III: A Phase III Multicenter, International, Randomized, Double-blind, Placebo-controlled Study of Doxorubicin Plus Palifosfamide-tris vs. Doxorubicin Plus Placebo in Patients With Front-line Metastatic Soft Tissue Sarcoma
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US
ANNOUNCE: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Doxorubicin Plus Olaratumab Versus Doxorubicin Plus Placebo in Patients With Advanced or Metastatic Soft Tissue Sarcoma
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US
A Multicenter, Randomized, Open-Label Phase 3 Study to Investigate the Efficacy and Safety of Aldoxorubicin Compared to Investigator's Choice in Subjects With Metastatic, Locally Advanced, or Unresectable Soft Tissue Sarcomas Who Either Relapsed or Were Refractory to Prior Non-Adjuvant Chemotherapy
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US
A Study of the Safety and Efficacy of the Combination of Gemcitabine and Docetaxel in Metastatic Soft Tissue Sarcoma
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US
A Multicenter, Randomized, Open-Label Phase 2b Study to Investigate the Preliminary Efficacy and Safety of INNO-206 (Doxorubicin-EMCH) Compared to Doxorubicin in Subjects with Metastatic, Locally Advanced, or Unresectable Soft Tissue Sarcoma
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US