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Sperimentazioni cliniche nazionali

Phase 2 Study of Systemic IL-6 Receptor Antagonist ACTEMRA (Tocilizumab) for the Treatment of Progressive/Recurrent Pediatric Adamantinomatous Craniopharyngioma -AU Institution: Information not provided - AU

TRANSCENDWORLD: A Phase 2, Single-arm, Multi-center Trial to Determine the Efficacy and Safety of JCAR017 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or With Other Aggressive B-Cell Malignancies - AT Institution: Information not provided - AT

Long-Term Follow-up Protocol for Subjects Treated with Gene-Modified T cells (Phase 2-3) - AT Institution: Information not provided - AT

OptiMATe - Optimizing MATRix as Remission Induction in PCNSL: De-escalated Induction Treatment in Newly Diagnosed Primary CNS Lymphoma - a Randomized Phase III Trial - AT Institution: Information not provided - AT

Open-label Single Arm Phase II Study on Pembrolizumab for Recurrent Primary Central Nervous System Lymphoma (PCNSL) - AT Allgemeines Krankenhaus der Stadt Wien Klinische Abteilung für Onkologie

SIOP CNS GCT II: Prospective Trial for the diagnosis and treatment of children, adolescents and young adults with Intracranial Germ Cell Tumours (phase IV) - AT Allgemeines Krankenhaus der Stadt Wien Klinische Abteilung für Neonatologie, Pädiatrische Intensivmedizin und Neuropädiatrie

STEP: Sorafenib Long Term Extension Program - BE Cliniques universitaires Saint-Luc - UCLouvain Pneumologie_Oncologie thoracique

Phase 2 Study of Systemic IL-6 Receptor Antagonist ACTEMRA (Tocilizumab) for the Treatment of Progressive/Recurrent Pediatric Adamantinomatous Craniopharyngioma -CA Institution: Information not provided - CA

Open-label, Non-randomized, Phase 2 Study Evaluating Efficacy and Safety of PQR309 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma AP-HP.Sorbonne Université - Hôpital de la Pitié-Salpêtrière Service de Neurologie 2 : Unité d'Onco-Neurologie

Phase II Study on the Management of Pediatric Craniopharyngioma by a Combination of Partial Surgical Resection, and Protontherapy CLCC Institut Curie Département d'Oncologie pédiatrique, adolescents et jeunes adultes

[18F]-Fludarabine PET/MR Imaging for the Assessment of Newly-diagnosed Primary Central Nervous System (CNS) Lymphoma : a Pilot PET-MRI Study Hôpital Pitié-Salpêtrière Service de Médecine nucléaire

REVRI : Phase II Study Evaluating the Efficacy of Lenalidomide in Association With Rituximab in Refractory or Relapse of Primary Central Nervous System Lymphoma (PCNSL) CLCC Hôpital René Huguenin - Institut Curie Département d'oncologie médicale - Hématologie

AcSé : Secured Access to Pembrolizumab for Adult Patients With Selected Rare Cancer Types (Phase II) CLCC Institut Gustave Roussy Département d'Innovation Thérapeutique et d'Essais Précoces

MARTA: Age-adjusted high-dose chemotherapy and autologous stem cell transplant in elderly and fit primary CNS lymphoma patients Universitätsklinikum Freiburg Klinik für Innere Medizin I - Hämatologie, Onkologie und Stammzelltransplantation

PRIMAIN: Treatment of patients over 65 years with Primary CNS Lymphoma: High-dose Methotrexate combined with Chemo-immunotherapy followed by maintenance therapy (Phase II) Klinikum Stuttgart - Katharinenhospital Klinik für Hämatologie, Onkologie und Palliativmedizin

MATRix - IELSG43 : High-dose chemotherapy and autologous stem cell transplant or consolidating conventional chemotherapy in primary CNS lymphoma - randomized phase III trial -DE- Klinikum Stuttgart - Katharinenhospital Klinik für Hämatologie, Onkologie und Palliativmedizin

VENOBI-CNS Study: Chemotherapy Free Treatment With Venetoclax and Obinutuzumab for Relapsed Primary CNS Lymphoma Patients - A Phase IB Study to Assess the Pharmacokinetics in the Cerebrospinal Fluid Klinikum Stuttgart - Katharinenhospital Klinik für Hämatologie, Onkologie und Palliativmedizin

Open-label, Non-randomized, Phase 2 Study Evaluating Efficacy and Safety of PQR309 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma - DE Charité - Universitätsmedizin Berlin (CCM) Medizinische Klinik mit Schwerpunkt Onkologie und Hämatologie (CCM)

SIOP CNS GCT II: Internationale, non-randomised, multicentre, prospective phase IV trial for the diagnosis and treatment of children and adolescents with Intracranial Germ Cell Tumor - DE Universitäts-Kinderklinik Bonn Abteilung für Pädiatrische Hämatologie/ Onkologie

Studio in aperto, a braccio singolo, di fase 1/2 che valuta la sicurezza e l'efficacia di Ponatinib per il trattamento delle leucemie ricorrenti o refrattarie o dei tumori solidi in pazienti pediatrici IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO U.O. di Oncoematologia

Phase 2 Study of Systemic IL-6 Receptor Antagonist ACTEMRA (Tocilizumab) for the Treatment of Progressive/Recurrent Pediatric Adamantinomatous Craniopharyngioma -GB GOSH NHS Foundatin Trust Great Ormond Street Hospital

Long-Term Follow-up Protocol for Subjects Treated with Gene-Modified T cells - ES Institution: Information not provided - ES

Effects of Exenatid on Weigth during diet and Caloric Restriction in patients with Craniopharyngioma and Hypothalamic obesity - SE Skåne University Hospital, Lund

LAHENE Study: Perioperative Levetiracetam for seizure prophylaxis in brain tumor patients. Prospective evaluation of side effects and efficacy (phase 2) Universitätsklinikum St. Pölten Karl Landsteiner Institut für klinische Neurologie und Neuropsychologie

REGO-SARC: Activity and Safety of Regorafenib in Patients With Metastatic Soft Tissue Sarcoma Previously Treated With Anthracycline-based Chemotherapy: a Multinational, Randomized, Phase II, Placebo-controlled Trial - AT Allgemeines Krankenhaus der Stadt Wien Klinische Abteilung für Onkologie

A Phase II, Open-label, Study in Subjects With BRAF V600E-Mutated Rare Cancers With Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib - AT Allgemeines Krankenhaus der Stadt Wien Klinische Abteilung für Onkologie

A randomized Phase 3, multicenter, Open-Label Study comparing TH-302 in Combination with Doxorubicin vs. Doxorubicin alone in subjects with locally advanced unresectable or metastatic soft tissue sarcoma - FR Institution: Information not provided - FR

Cilengitide (EMD121974) in combination with irradiation in children and young adults with newly diagnosed diffuse intrinsic pontine glioma : Phase I study CLCC Oscar Lambret Unité d'oncologie pédiatrique

OVIMA : Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma CLCC Oscar Lambret Unité d'oncologie pédiatrique

A Study Evaluating Dexamfetamine Sulphate in Patients With Glioma Suffering From Severe Asthenia. A Phase III Double-blind Randomized Placebo-controlled Trial AP-HP.Sorbonne Université - Hôpital de la Pitié-Salpêtrière Unité Fonctionnelle Epilepsie

BIOMEDE: Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication (Phase II) - FR CLCC Institut Gustave Roussy Département de Cancérologie de l'enfant et de l'adolescent

CIRSAR: Phase III Trial Investigating the Potential Benefit of Intensified Peri-operative Chemotherapy With in High-risk CINSARC Patients With Resectable Soft-tissue SARComas CLCC Institut Bergonié Département d'oncologie médicale - Sarcomes

EXTREM ION: Neoadjuvant Irradiation of Extremity Soft Tissue Sarcoma With Ions Neurologische Universitätsklinik Heidelberg Klinik für Radioonkologie und Strahlentherapie

PIVOT IO 020: Phase 1/2 Study of Bempegaldesleukin in Combination With Nivolumab in Children, Adolescents, and Young Adults With Recurrent or Refractory Malignancies - DE Institution: Information not provided - DE

OlaReDo: Efficacy of Olaratumab and Rechallenge With Doxorubicin in Anthracycline Pretreated, Advanced Soft Tissue Sarcoma Patients. An Exploratory Phase-II Study Krankenhaus Nordwest GmbH Institut für Klinische Krebsforschung IKF GmbH

MEN-301: A Phase 3 Multicenter Study of Gleolan (Aminolevulinic Acid Hydrochloride) to Enhance Visualization of Tumor in Patients With Newly Diagnosed or Recurrent Meningiomas -DE Universitätsklinikum Münster Klinik für Neurochirurgie

European Paediatric Soft Tissue Sarcoma Study Group protocol for Localized Non-Rhabdomyosarcoma Soft Tissue Sarcomas 2005 (phase III) - IE Children's Health Ireland @ Crumlin Department of Paediatric Haematology and Oncology

A Phase II Study of Pembrolizumab in Patients With Malignant Peripheral Nerve Sheath Tumor (MPNST), Not Eligible for Curative Surgery (NO) Oslo University Hospital, Radiumhospitalet Department of Oncolocy, Oslo University Hospital, Radiumhospitalet

Phase II open-label global study to evaluate the effect of dabrafenib in combination with trametinib in children and adolescent patients with BRAF V600 mutation positive relapsed or refractory High Grade Glioma (HGG) - ES Institution: Information not provided - ES

Treatment of Recurrent or Progressive Meningiomas With the Radiolabelled Somatostatin Antagonist 177Lu-Satoreotide (PROMENADE-Study) Universitätsspital Basel Neurochirurgie

LSCI-NSURG: Intraoperative Laser Speckle Contrast Imaging to Assess Blood Flow During Neurosurgery Universitätsspital Inselspital Universitätsklinik für Neurochirurgie

ANNOUNCE 2: A Phase 1b (Open-Label) / Phase 2 (Randomized,Double-Blinded) Study Evaluating Gemcitabine andDocetaxel With or Without Olaratumab in the Treatment ofAdvanced Soft Tissue Sarcoma -GB Institution: Information not provided - CH

PazoQol: Quality of life in patients with non-adipocyte soft tissue sarcoma underpalliative chemotherapy or pazopanib - a randomized, controlled trial - CH Institution: Information not provided - CH

Met Med Can: Phase III Randomized Double-blind Placebo-controlled Trial of Metformin for Cognitive Recovery and White Matter Growth in Paediatric - AU Institution: Information not provided - AU

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - AT Kepler Universitätsklinikum - Med Campus IV. Universitätsklinik für Kinder- und Jugendheilkunde

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - AT Universitätsklinikum der Paracelsus Medizinischen Privatuniversität Universitätsklinik für Kinder- und Jugendheilkunde

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - AT Medizinische Universität Graz Klinische Abteilung für pädiatrische Hämato-Onkologie

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - AT Medizinische Universität Innsbruck Pädiatrie I

SIOP-HRMB: An International Prospective Trial on High-Risk Medulloblastoma in Patients Older than 3 Years (Phase 3) - AT Institution: Information not provided - AT

HIT-HGG-2013: International cooperative Phase III trial of the HIT-HGG study group for the treatment of high grade glioma, diffuse intrinsic pontine glioma, and gliomatosis cerebri in children and adolescents < 18 years - AT Institution: Information not provided - AT

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - AT Allgemeines Krankenhaus der Stadt Wien Klinische Abteilung für Neonatologie, Pädiatrische Intensivmedizin und Neuropädiatrie

INFORM2 NivEnt: Exploratory Multinational Phase I/II Combination Study of Nivolumab and Entinostat in Children and Adolescents With Refractory High-risk Malignancies - AT St. Anna Kinderspital Zentrum für Kinder- und Jugendheilkunde

TAVAREC: Randomized trial assessing the significance of Bevacizumab in recurrent grade II and Grade III gliomas. The TAVAREC trial (Phase II) - BE Institution: Information not provided - BE

Molecular and Cellular Print Medical Device Validation in Adult Glioma Tumors (Phase I) - FR Centre Hospitalier Universitaire Grenoble Alpes

Tazemetostat Rollover Study (TRuST): An Open-Label, Rollover Study (Phase II) - FR CLCC Institut Bergonié Département d'oncologie médicale - Sarcomes

INFORM2 NivEnt: exploratory multinational phase I/II combination study of Nivolumab and Entinostat in children and adolescents with refractory high-risk malignancies Deutsches Krebsforschungszentrum Klinische Kooperationseinheit Pädiatrische Onkologie

TAVAREC (EORTC 26091) - Randomized trial assessing the significance of Bevacizumab in recurrent Grade II and Grade III Glioma (Phase II) - DE Neurologische Universitätsklinik Heidelberg Abteilung für Neuroonkologie

INFORM2 NivEnt: exploratory multinational phase I/II combination study of Nivolumab and Entinostat in children and adolescents with refractory high-risk malignancies Universitätsklinikum Regensburg Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation

HIT-HGG-CilMetro: Cilengitide and Metronomic Temozolomide for relapsed or refractory high grade Gliomas or Diffuse Intrinsic Pontine Gliomas in children and adolescents - Prospective non- randomised phase II study Universitätsmedizin Göttingen Klinik für Kinder- und Jugendmedizin

Autologous Dendritic Cells and Metronomic Cyclophosphamide for Relapsed High-Grade Gliomas in Children and Adolescents Universitätsmedizin Göttingen Klinik für Kinder- und Jugendmedizin

INFORM2 NivEnt: exploratory multinational phase I/II combination study of Nivolumab and Entinostat in children and adolescents with refractory high-risk malignancies Universitätsklinikum Essen Klinik für Kinderheilkunde III

STING: Comparing a Treatment Strategy With Levetiracetam Versus Treatment With Valproic Acid in Glioma Patients With a First Seizure (phase IV) LUMC - Leids Universitair Medisch Centrum Afdeling Neurologie

Cooperative Multicenter Study for Children and Adolescents With Low Grade Glioma - PL Instytut "Pomnik-Centrum Zdrowia Dziecka" Klinika Onkologii IP-CZD

Cooperative Multicenter Study for Children and Adolescents With Low Grade Glioma - PT Centro Hospitalar Universitário de S. João, EPE Unidade de Hematologia e Oncologia Pediátrica

A Phase 2 clinical study of pomalidomide (CC-4047) monotherapy for children and young adults with recurrent or progressive primary brain tumors - ES Institution: Information not provided - ES

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - ES Hospital Infantil Universitario Niño Jesús Servicio de Oncohematología

plexifpc - Treatment of NF1-related Plexiform Neurofibroma With Trametinib; a Single Arm, Open-label Trial With the Goals of Volumetric Partial Remission and Pain Relief - SE Skåne University Hospital, Lund

A Phase 2 clinical study of pomalidomide (CC-4047) monotherapy for children and young adults with recurrent or progressive primary brain tumors. -GB Institution: Information not provided - CH

SIOP-Ependymoma-II: An International Clinical Program for the Diagnosis and Treatment of Children, Adolescents and Young Adults With Ependymoma (Phase II-III) - AT Medizinische Universität Graz Klinische Abteilung für pädiatrische Hämato-Onkologie

Phase II Feasibility Study Using ch14.18/CHO Antibody and Subcutaneous Interleukin 2 After Haploidentical Stem Cell Transplantation in Children With Relapsed Neuroblastoma - AT Medizinische Universität Graz Klinische Abteilung für pädiatrische Hämato-Onkologie

VERITAS: An International Multicenter Phase II Randomised Trial Evaluating and Comparing Two Intensification Treatment Strategies for Metastatic Neuroblastoma Patients With a Poor Response to Induction Chemotherapy - AT Institution: Information not provided - AT

A Pilot and Surgical Study of Larotrectinib for Treatment of Children With Newly-Diagnosed High-Grade Glioma With NTRK Fusion (Phase 1) - AT Institution: Information not provided - AT

Phase III Intergroup Study of Radiotherapy With Concomitant and Adjuvant Temozolomide Versus Radiotherapy With Adjuvant PCV Chemotherapy in Patients With 1p/19q Co-deleted Anaplastic Glioma or Low Grade Glioma - AT Allgemeines Krankenhaus der Stadt Wien Klinische Abteilung für Onkologie

VINILO: Phase I-II Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults With Refractory or Recurrent Low-Grade Glioma - AT Allgemeines Krankenhaus der Stadt Wien Klinische Abteilung für Neonatologie, Pädiatrische Intensivmedizin und Neuropädiatrie

High Risk Neuroblastoma Study 1 of SIOP-Europe (SIOPEN) (Phase III) - AT St. Anna Kinderspital Zentrum für Kinder- und Jugendheilkunde

Phase II Feasibility Study Using ch14.18/CHO Antibody and Subcutaneous Interleukin 2 After Haploidentical Stem Cell Transplantation in Children With Relapsed Neuroblastoma - AT St. Anna Kinderspital Zentrum für Kinder- und Jugendheilkunde

Phase 2 Study of Systemic IL-6 Receptor Antagonist ACTEMRA (Tocilizumab) for the Treatment of Progressive/Recurrent Pediatric Adamantinomatous Craniopharyngioma -AU
Institution: Information not provided - AU

TRANSCENDWORLD: A Phase 2, Single-arm, Multi-center Trial to Determine the Efficacy and Safety of JCAR017 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or With Other Aggressive B-Cell Malignancies - AT
Institution: Information not provided - AT

Long-Term Follow-up Protocol for Subjects Treated with Gene-Modified T cells (Phase 2-3) - AT
Institution: Information not provided - AT

OptiMATe - Optimizing MATRix as Remission Induction in PCNSL: De-escalated Induction Treatment in Newly Diagnosed Primary CNS Lymphoma - a Randomized Phase III Trial - AT
Institution: Information not provided - AT

Open-label Single Arm Phase II Study on Pembrolizumab for Recurrent Primary Central Nervous System Lymphoma (PCNSL) - AT
Allgemeines Krankenhaus der Stadt Wien

Klinische Abteilung für Onkologie

SIOP CNS GCT II: Prospective Trial for the diagnosis and treatment of children, adolescents and young adults with Intracranial Germ Cell Tumours (phase IV) - AT
Allgemeines Krankenhaus der Stadt Wien

Klinische Abteilung für Neonatologie, Pädiatrische Intensivmedizin und Neuropädiatrie

STEP: Sorafenib Long Term Extension Program - BE
Cliniques universitaires Saint-Luc - UCLouvain

Pneumologie_Oncologie thoracique

Phase 2 Study of Systemic IL-6 Receptor Antagonist ACTEMRA (Tocilizumab) for the Treatment of Progressive/Recurrent Pediatric Adamantinomatous Craniopharyngioma -CA
Institution: Information not provided - CA

Open-label, Non-randomized, Phase 2 Study Evaluating Efficacy and Safety of PQR309 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma
AP-HP.Sorbonne Université - Hôpital de la Pitié-Salpêtrière

Service de Neurologie 2 : Unité d'Onco-Neurologie

Phase II Study on the Management of Pediatric Craniopharyngioma by a Combination of Partial Surgical Resection, and Protontherapy
CLCC Institut Curie

Département d'Oncologie pédiatrique, adolescents et jeunes adultes

[18F]-Fludarabine PET/MR Imaging for the Assessment of Newly-diagnosed Primary Central Nervous System (CNS) Lymphoma : a Pilot PET-MRI Study
Hôpital Pitié-Salpêtrière

Service de Médecine nucléaire

REVRI : Phase II Study Evaluating the Efficacy of Lenalidomide in Association With Rituximab in Refractory or Relapse of Primary Central Nervous System Lymphoma (PCNSL)
CLCC Hôpital René Huguenin - Institut Curie

Département d'oncologie médicale - Hématologie

AcSé : Secured Access to Pembrolizumab for Adult Patients With Selected Rare Cancer Types (Phase II)
CLCC Institut Gustave Roussy

Département d'Innovation Thérapeutique et d'Essais Précoces

MARTA: Age-adjusted high-dose chemotherapy and autologous stem cell transplant in elderly and fit primary CNS lymphoma patients
Universitätsklinikum Freiburg

Klinik für Innere Medizin I - Hämatologie, Onkologie und Stammzelltransplantation

PRIMAIN: Treatment of patients over 65 years with Primary CNS Lymphoma: High-dose Methotrexate combined with Chemo-immunotherapy followed by maintenance therapy (Phase II)
Klinikum Stuttgart - Katharinenhospital

Klinik für Hämatologie, Onkologie und Palliativmedizin

MATRix - IELSG43 : High-dose chemotherapy and autologous stem cell transplant or consolidating conventional chemotherapy in primary CNS lymphoma - randomized phase III trial -DE-
Klinikum Stuttgart - Katharinenhospital

Klinik für Hämatologie, Onkologie und Palliativmedizin

VENOBI-CNS Study: Chemotherapy Free Treatment With Venetoclax and Obinutuzumab for Relapsed Primary CNS Lymphoma Patients - A Phase IB Study to Assess the Pharmacokinetics in the Cerebrospinal Fluid
Klinikum Stuttgart - Katharinenhospital

Klinik für Hämatologie, Onkologie und Palliativmedizin

Open-label, Non-randomized, Phase 2 Study Evaluating Efficacy and Safety of PQR309 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma - DE
Charité - Universitätsmedizin Berlin (CCM)

Medizinische Klinik mit Schwerpunkt Onkologie und Hämatologie (CCM)

SIOP CNS GCT II: Internationale, non-randomised, multicentre, prospective phase IV trial for the diagnosis and treatment of children and adolescents with Intracranial Germ Cell Tumor - DE
Universitäts-Kinderklinik Bonn

Abteilung für Pädiatrische Hämatologie/ Onkologie

Studio in aperto, a braccio singolo, di fase 1/2 che valuta la sicurezza e l'efficacia di Ponatinib per il trattamento delle leucemie ricorrenti o refrattarie o dei tumori solidi in pazienti pediatrici
IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO

U.O. di Oncoematologia

Phase 2 Study of Systemic IL-6 Receptor Antagonist ACTEMRA (Tocilizumab) for the Treatment of Progressive/Recurrent Pediatric Adamantinomatous Craniopharyngioma -GB
GOSH NHS Foundatin Trust

Great Ormond Street Hospital

Long-Term Follow-up Protocol for Subjects Treated with Gene-Modified T cells - ES
Institution: Information not provided - ES

Effects of Exenatid on Weigth during diet and Caloric Restriction in patients with Craniopharyngioma and Hypothalamic obesity - SE
Skåne University Hospital, Lund

LAHENE Study: Perioperative Levetiracetam for seizure prophylaxis in brain tumor patients. Prospective evaluation of side effects and efficacy (phase 2)
Universitätsklinikum St. Pölten

Karl Landsteiner Institut für klinische Neurologie und Neuropsychologie

REGO-SARC: Activity and Safety of Regorafenib in Patients With Metastatic Soft Tissue Sarcoma Previously Treated With Anthracycline-based Chemotherapy: a Multinational, Randomized, Phase II, Placebo-controlled Trial - AT
Allgemeines Krankenhaus der Stadt Wien

Klinische Abteilung für Onkologie

A Phase II, Open-label, Study in Subjects With BRAF V600E-Mutated Rare Cancers With Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib - AT
Allgemeines Krankenhaus der Stadt Wien

Klinische Abteilung für Onkologie

A randomized Phase 3, multicenter, Open-Label Study comparing TH-302 in Combination with Doxorubicin vs. Doxorubicin alone in subjects with locally advanced unresectable or metastatic soft tissue sarcoma - FR
Institution: Information not provided - FR

Cilengitide (EMD121974) in combination with irradiation in children and young adults with newly diagnosed diffuse intrinsic pontine glioma : Phase I study
CLCC Oscar Lambret

Unité d'oncologie pédiatrique

OVIMA : Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma
CLCC Oscar Lambret

Unité d'oncologie pédiatrique

A Study Evaluating Dexamfetamine Sulphate in Patients With Glioma Suffering From Severe Asthenia. A Phase III Double-blind Randomized Placebo-controlled Trial
AP-HP.Sorbonne Université - Hôpital de la Pitié-Salpêtrière

Unité Fonctionnelle Epilepsie

BIOMEDE: Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication (Phase II) - FR
CLCC Institut Gustave Roussy

Département de Cancérologie de l'enfant et de l'adolescent

CIRSAR: Phase III Trial Investigating the Potential Benefit of Intensified Peri-operative Chemotherapy With in High-risk CINSARC Patients With Resectable Soft-tissue SARComas
CLCC Institut Bergonié

Département d'oncologie médicale - Sarcomes

EXTREM ION: Neoadjuvant Irradiation of Extremity Soft Tissue Sarcoma With Ions
Neurologische Universitätsklinik Heidelberg

Klinik für Radioonkologie und Strahlentherapie

PIVOT IO 020: Phase 1/2 Study of Bempegaldesleukin in Combination With Nivolumab in Children, Adolescents, and Young Adults With Recurrent or Refractory Malignancies - DE
Institution: Information not provided - DE

OlaReDo: Efficacy of Olaratumab and Rechallenge With Doxorubicin in Anthracycline Pretreated, Advanced Soft Tissue Sarcoma Patients. An Exploratory Phase-II Study
Krankenhaus Nordwest GmbH

Institut für Klinische Krebsforschung IKF GmbH

MEN-301: A Phase 3 Multicenter Study of Gleolan (Aminolevulinic Acid Hydrochloride) to Enhance Visualization of Tumor in Patients With Newly Diagnosed or Recurrent Meningiomas -DE
Universitätsklinikum Münster

Klinik für Neurochirurgie

European Paediatric Soft Tissue Sarcoma Study Group protocol for Localized Non-Rhabdomyosarcoma Soft Tissue Sarcomas 2005 (phase III) - IE
Children's Health Ireland @ Crumlin

Department of Paediatric Haematology and Oncology

A Phase II Study of Pembrolizumab in Patients With Malignant Peripheral Nerve Sheath Tumor (MPNST), Not Eligible for Curative Surgery (NO)
Oslo University Hospital, Radiumhospitalet

Department of Oncolocy, Oslo University Hospital, Radiumhospitalet

Phase II open-label global study to evaluate the effect of dabrafenib in combination with trametinib in children and adolescent patients with BRAF V600 mutation positive relapsed or refractory High Grade Glioma (HGG) - ES
Institution: Information not provided - ES

Treatment of Recurrent or Progressive Meningiomas With the Radiolabelled Somatostatin Antagonist 177Lu-Satoreotide (PROMENADE-Study)
Universitätsspital Basel

Neurochirurgie

LSCI-NSURG: Intraoperative Laser Speckle Contrast Imaging to Assess Blood Flow During Neurosurgery
Universitätsspital Inselspital

Universitätsklinik für Neurochirurgie

ANNOUNCE 2: A Phase 1b (Open-Label) / Phase 2 (Randomized,Double-Blinded) Study Evaluating Gemcitabine andDocetaxel With or Without Olaratumab in the Treatment ofAdvanced Soft Tissue Sarcoma -GB
Institution: Information not provided - CH

PazoQol: Quality of life in patients with non-adipocyte soft tissue sarcoma underpalliative chemotherapy or pazopanib - a randomized, controlled trial - CH
Institution: Information not provided - CH

Met Med Can: Phase III Randomized Double-blind Placebo-controlled Trial of Metformin for Cognitive Recovery and White Matter Growth in Paediatric - AU
Institution: Information not provided - AU

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - AT
Kepler Universitätsklinikum - Med Campus IV.

Universitätsklinik für Kinder- und Jugendheilkunde

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - AT
Universitätsklinikum der Paracelsus Medizinischen Privatuniversität

Universitätsklinik für Kinder- und Jugendheilkunde

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - AT
Medizinische Universität Graz

Klinische Abteilung für pädiatrische Hämato-Onkologie

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - AT
Medizinische Universität Innsbruck

Pädiatrie I

SIOP-HRMB: An International Prospective Trial on High-Risk Medulloblastoma in Patients Older than 3 Years (Phase 3) - AT
Institution: Information not provided - AT

HIT-HGG-2013: International cooperative Phase III trial of the HIT-HGG study group for the treatment of high grade glioma, diffuse intrinsic pontine glioma, and gliomatosis cerebri in children and adolescents < 18 years - AT
Institution: Information not provided - AT

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - AT
Allgemeines Krankenhaus der Stadt Wien

Klinische Abteilung für Neonatologie, Pädiatrische Intensivmedizin und Neuropädiatrie

INFORM2 NivEnt: Exploratory Multinational Phase I/II Combination Study of Nivolumab and Entinostat in Children and Adolescents With Refractory High-risk Malignancies - AT
St. Anna Kinderspital

Zentrum für Kinder- und Jugendheilkunde

TAVAREC: Randomized trial assessing the significance of Bevacizumab in recurrent grade II and Grade III gliomas. The TAVAREC trial (Phase II) - BE
Institution: Information not provided - BE

Molecular and Cellular Print Medical Device Validation in Adult Glioma Tumors (Phase I) - FR
Centre Hospitalier Universitaire Grenoble Alpes

Tazemetostat Rollover Study (TRuST): An Open-Label, Rollover Study (Phase II) - FR
CLCC Institut Bergonié

Département d'oncologie médicale - Sarcomes

INFORM2 NivEnt: exploratory multinational phase I/II combination study of Nivolumab and Entinostat in children and adolescents with refractory high-risk malignancies
Deutsches Krebsforschungszentrum

Klinische Kooperationseinheit Pädiatrische Onkologie

TAVAREC (EORTC 26091) - Randomized trial assessing the significance of Bevacizumab in recurrent Grade II and Grade III Glioma (Phase II) - DE
Neurologische Universitätsklinik Heidelberg

Abteilung für Neuroonkologie

INFORM2 NivEnt: exploratory multinational phase I/II combination study of Nivolumab and Entinostat in children and adolescents with refractory high-risk malignancies
Universitätsklinikum Regensburg

Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation

HIT-HGG-CilMetro: Cilengitide and Metronomic Temozolomide for relapsed or refractory high grade Gliomas or Diffuse Intrinsic Pontine Gliomas in children and adolescents - Prospective non- randomised phase II study
Universitätsmedizin Göttingen

Klinik für Kinder- und Jugendmedizin

Autologous Dendritic Cells and Metronomic Cyclophosphamide for Relapsed High-Grade Gliomas in Children and Adolescents
Universitätsmedizin Göttingen

Klinik für Kinder- und Jugendmedizin

INFORM2 NivEnt: exploratory multinational phase I/II combination study of Nivolumab and Entinostat in children and adolescents with refractory high-risk malignancies
Universitätsklinikum Essen

Klinik für Kinderheilkunde III

STING: Comparing a Treatment Strategy With Levetiracetam Versus Treatment With Valproic Acid in Glioma Patients With a First Seizure (phase IV)
LUMC - Leids Universitair Medisch Centrum

Afdeling Neurologie

Cooperative Multicenter Study for Children and Adolescents With Low Grade Glioma - PL
Instytut "Pomnik-Centrum Zdrowia Dziecka"

Klinika Onkologii IP-CZD

Cooperative Multicenter Study for Children and Adolescents With Low Grade Glioma - PT
Centro Hospitalar Universitário de S. João, EPE

Unidade de Hematologia e Oncologia Pediátrica

A Phase 2 clinical study of pomalidomide (CC-4047) monotherapy for children and young adults with recurrent or progressive primary brain tumors - ES
Institution: Information not provided - ES

MEMMAT: A Phase II study of metronomic and targeted anti-angiogenesis therapy for children with recurrent/progressive medulloblastoma - ES
Hospital Infantil Universitario Niño Jesús

Servicio de Oncohematología

plexifpc - Treatment of NF1-related Plexiform Neurofibroma With Trametinib; a Single Arm, Open-label Trial With the Goals of Volumetric Partial Remission and Pain Relief - SE
Skåne University Hospital, Lund

A Phase 2 clinical study of pomalidomide (CC-4047) monotherapy for children and young adults with recurrent or progressive primary brain tumors. -GB
Institution: Information not provided - CH

SIOP-Ependymoma-II: An International Clinical Program for the Diagnosis and Treatment of Children, Adolescents and Young Adults With Ependymoma (Phase II-III) - AT
Medizinische Universität Graz

Klinische Abteilung für pädiatrische Hämato-Onkologie

Phase II Feasibility Study Using ch14.18/CHO Antibody and Subcutaneous Interleukin 2 After Haploidentical Stem Cell Transplantation in Children With Relapsed Neuroblastoma - AT
Medizinische Universität Graz

Klinische Abteilung für pädiatrische Hämato-Onkologie

VERITAS: An International Multicenter Phase II Randomised Trial Evaluating and Comparing Two Intensification Treatment Strategies for Metastatic Neuroblastoma Patients With a Poor Response to Induction Chemotherapy - AT
Institution: Information not provided - AT

A Pilot and Surgical Study of Larotrectinib for Treatment of Children With Newly-Diagnosed High-Grade Glioma With NTRK Fusion (Phase 1) - AT
Institution: Information not provided - AT

Phase III Intergroup Study of Radiotherapy With Concomitant and Adjuvant Temozolomide Versus Radiotherapy With Adjuvant PCV Chemotherapy in Patients With 1p/19q Co-deleted Anaplastic Glioma or Low Grade Glioma - AT
Allgemeines Krankenhaus der Stadt Wien

Klinische Abteilung für Onkologie

VINILO: Phase I-II Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults With Refractory or Recurrent Low-Grade Glioma - AT
Allgemeines Krankenhaus der Stadt Wien

Klinische Abteilung für Neonatologie, Pädiatrische Intensivmedizin und Neuropädiatrie

High Risk Neuroblastoma Study 1 of SIOP-Europe (SIOPEN) (Phase III) - AT
St. Anna Kinderspital

Zentrum für Kinder- und Jugendheilkunde

Phase II Feasibility Study Using ch14.18/CHO Antibody and Subcutaneous Interleukin 2 After Haploidentical Stem Cell Transplantation in Children With Relapsed Neuroblastoma - AT
St. Anna Kinderspital

Zentrum für Kinder- und Jugendheilkunde

BEACON-Neuroblastoma Trial: A Randomised Phase IIb Trial of Bevacizumab Added to Temozolomide ± Irinotecan for Children With Refractory/Relapsed Neuroblastoma - AT
St. Anna Kinderspital

Zentrum für Kinder- und Jugendheilkunde

Phase II Study of Monoclonal Antibody ch14.18/CHO Continuous Infusion in Patients With Primary Refractory or Relapsed Neuroblastoma - AT
St. Anna Kinderspital

Zentrum für Kinder- und Jugendheilkunde

RIST-rNB-2011: Prospective, Open Label, Randomized Phase II Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-risk Neuroblastoma - AT
St. Anna Kinderspital

Zentrum für Kinder- und Jugendheilkunde

LINES: European Low and Intermediate Risk Neuroblastoma Protocol (Phase III) - AT
St. Anna Kinderspital

Zentrum für Kinder- und Jugendheilkunde