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Ensaio (s) clínico (s) nacional (is)

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

VASE: Phase III multicentric study evaluating the efficacy and safety of sirolimus in Vascular Anomalies that are refractory to standard care - BE
Cliniques universitaires Saint-Luc - UCLouvain
Centre des Malformations Vasculaires

NORMANDIE
CAEN

Baden-Württemberg
MANNHEIM

EVA Study: Phase II, multicenter, open-label, single-arm trial in advanced and relapsed Angiosarcomas, to evaluate the efficacy of pazopanib (Votrient) in combination with standard of care treatment paclitaxel ( Evaluation of Votrient in angiosarcoma - EVA) - DE
Universitätsmedizin Mannheim
Sarkom-Zentrum

Baden-Württemberg
STUTTGART
EURO-B.O.S.S.: A European treatment protocol for bone sarcoma in patients older than 40 years - DE
Klinikum Stuttgart - Standort Olgahospital
COSS (Cooperative OsteoSarkom Studiengruppe) Studienzentrale

Berlin
BERLIN

PazoQol: Quality of Life in Patients With Non-adipocyte Soft Tissue Sarcoma Under Palliative Chemotherapy or Pazopanib - a Randomized, Controlled Trial -DE-
Helios Klinikum Emil von Behring
Klinik für Onkologie

Hessen
FRANKFURT AM MAIN

OlaReDo: Efficacy of Olaratumab and Rechallenge With Doxorubicin in Anthracycline Pretreated, Advanced Soft Tissue Sarcoma Patients. An Exploratory Phase-II Study
Krankenhaus Nordwest GmbH
Institut für Klinisch-Onkologische Forschung

Nordrhein-Westfalen
MÜNSTER
FIBROSARC: A phase III study comparing the efficacy of the combination of doxorubicin and the tumor-targeting human antibody-cytokine fusion protein L19TNF to doxorubicin alone as first-line therapy in patients with advanced or metastatic soft tissue sarcoma
Universitätsklinikum Münster
Medizinische Klinik und Poliklinik A

WIEN
ADDRESS: NOT PROVIDED - AT
TAPPAS: A Randomized Phase 3 Trial of TRC105 and Pazopanib Versus Pazopanib Alone in Patients With Advanced Angiosarcoma - AT
Institution: Information not provided - AT

WIEN
WIEN
REGO-SARC: Activity and Safety of Regorafenib in Patients With Metastatic Soft Tissue Sarcoma Previously Treated With Anthracycline-based Chemotherapy: a Multinational, Randomized, Phase II, Placebo-controlled Trial - AT
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Onkologie

WIEN
WIEN

EVA (Evaluation of Votrient in angiosarcoma): Single-arm, Multicenter, Open Label Phase II Trial to Evaluate the Efficacy of Pazopanib in Combination With Paclitaxel in Advanced and Relapsed Angiosarcoma - AT
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Onkologie

Andalucía
SEVILLA

GEIS-51: Phase II multicenter trial of palbociclib in second line of advanced sarcomas with CDK4 overexpression - ES
Hospital Universitario Virgen del Rocío
MUsculoSkeletal Tumor Board of Excellence Sevilla (MUSTBE SEVILLA)

Andalucía
SEVILLA

GEIS-52: Phase I-II trial of sunitinib plus nivolumab after standard treatment in advanced soft tissue and bone sarcomas - ES
Hospital Universitario Virgen del Rocío
MUsculoSkeletal Tumor Board of Excellence Sevilla (MUSTBE SEVILLA)

Andalucía
SEVILLA
ANNOUNCE 2: A Phase 1b (Open-Label) / Phase 2 (Randomized, Double-Blinded) Study Evaluating Gemcitabine and Docetaxel With or Without Olaratumab in the Treatment of Advanced Soft Tissue Sarcoma - ES
Hospital Universitario Virgen del Rocío
Unidad de Oncología Médica, Oncología Radioterápica y Radiofísica

Cataluña
BADALONA

GEIS-51: Phase II multicenter trial of palbociclib in second line of advanced sarcomas with CDK4 overexpression - ES
ICO Badalona - Hospital Germans Trias i Pujol
Servicio de Oncología Médica

Cataluña
BARCELONA
ANNOUNCE 2: A Phase 1b (Open-Label) / Phase 2 (Randomized, Double-Blinded) Study Evaluating Gemcitabine and Docetaxel With or Without Olaratumab in the Treatment of Advanced Soft Tissue Sarcoma - ES
Hospital Universitari Vall d'Hebron
Servicio de Oncología Médica

Madrid
MADRID
ANNOUNCE 2: A Phase 1b (Open-Label) / Phase 2 (Randomized, Double-Blinded) Study Evaluating Gemcitabine and Docetaxel With or Without Olaratumab in the Treatment of Advanced Soft Tissue Sarcoma - ES
Hospital Universitario 12 de Octubre
Servicio de Oncología Médica

Madrid
MADRID
ANNOUNCE 2: A Phase 1b (Open-Label) / Phase 2 (Randomized, Double-Blinded) Study Evaluating Gemcitabine and Docetaxel With or Without Olaratumab in the Treatment of Advanced Soft Tissue Sarcoma - ES
Hospital Universitario La Paz
Servicio de Oncología Médica

Massachusetts
BOSTON

A Randomized Phase 2 Study of Vincristine Versus Sirolimus to Treat High Risk Kaposiform Hemangioendothelioma (KHE) - US
Boston Children's Hospital

AUVERGNE-RHONE-ALPES
ADDRESS: NOT PROVIDED - FR

A randomized Phase 3, multicenter, Open-Label Study comparing TH-302 in Combination with Doxorubicin vs. Doxorubicin alone in subjects with locally advanced unresectable or metastatic soft tissue sarcoma - FR
Institution: Information not provided - FR

AUVERGNE-RHONE-ALPES
ADDRESS: NOT PROVIDED - FR


ANITA: A Phase II Multicenter Study Comparing the Efficacy of the Oral Angiogenesis Inhibitor Nintedanib With the Intravenous Cytotoxic Compound Ifosfamide for Treatment of Patients With Advanced Metastatic Soft Tissue Sarcoma After Failure of Systemic Non-oxazaphosporine-based First Line Chemotherapy for Inoperable Disease - FR
Institution: Information not provided - FR

AUVERGNE-RHONE-ALPES
LYON
Multicenter phase I/II study of continuous dosing of Sunitinib in non-GIST sarcomas with concomitant radiation therapy.
CLCC Léon Bérard
Radiothérapie

HAUTS-DE-FRANCE
AMIENS

MAV-RAPA: Prospective Evaluation of the Efficacy of Sirolimus (Rapamune®) in the Treatment of Severe Arteriovenous Malformations
CHU Amiens-Picardie - Site Sud
Service de Chirurgie Maxillo-Faciale (CMF) et Stomatologie

HAUTS-DE-FRANCE
LILLE

ANGIO-TAX-PLUS - Phase II study, multicenter, randomized, stratified, evaluating the efficacy of weekly paclitaxel, in association or not with bevacizumab in the treatment of metastatic or locally advanced angiosarcomas not accessible to surgery.
CLCC Oscar Lambret
Département de cancérologie générale

LAZIO
ROMA

A Phase 1/2 Study of ARQ 092 in Patients with Overgrowth Diseases and/or Vascular Anomalies with Genetic Alterations of the PI3K/AKT Pathway
IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO
Ambulatorio Polispecialistico per le Malattie Rare

LAZIO
ROMA
Phase II trial for the treatment of advanced Kaposi's Sarcoma with the HIV protease inhibitor Indinavir in combination with chemotherapy
ISS - Istituto Superiore di Sanità
Centro Nazionale AIDS

Greater Manchester
MANCHESTER

TRUSTS: A Phase IIb/III Multicenter Study Comparing the Efficacy of TRabectedin Administered as a 3-Hour or 24-Hour Infusion to Doxorubicin in Patients With Advanced or Metastatic Untreated Soft Tissue Sarcoma - UK
Manchester University NHS Foundation Trust - Manchester Royal Infirmary
Department of Orthopaedic Surgery

South Yorkshire
SHEFFIELD
VORTEX: Randomised Trial of Post-Operative Radiotherapy Given to Adult Patients With Extremity Soft Tissue Sarcoma (Phase III)
Weston Park Hospital
Cancer Clinical Trials Centre

South Yorkshire
SHEFFIELD
Axi-STS: A clinicopathological phase II study of axitinib in patients with advanced angiosarcoma and other soft tissue sarcomas
Weston Park Hospital
Cancer Clinical Trials Centre

Suisse Romande
ADDRESS: NOT PROVIDED - CH
ANNOUNCE 2: A Phase 1b (Open-Label) / Phase 2 (Randomized,Double-Blinded) Study Evaluating Gemcitabine andDocetaxel With or Without Olaratumab in the Treatment ofAdvanced Soft Tissue Sarcoma -GB
Institution: Information not provided - CH

Suisse Romande
ADDRESS: NOT PROVIDED - CH
PazoQol: Quality of life in patients with non-adipocyte soft tissue sarcoma underpalliative chemotherapy or pazopanib - a randomized, controlled trial - CH
Institution: Information not provided - CH

Ontario
TORONTO

Topical Anti-angiogenic Therapy for Telangiectasia in HHT: Proof of Concept
St. Michael's Hospital
Keenan Research Centre

AUVERGNE-RHONE-ALPES
BRON
BABH Study: Efficacy and Safety of Bevacizumab on Severe Bleedings Associated With Hemorrhagic Hereditary Telangiectasia (HHT). A National, Multicenter Phase III Study
CHU de Lyon HCL - GH Est-Hôpital Femme Mère Enfant
Service de génétique

LOMBARDIA
PAVIA

Efficacy of Thalidomide in the Treatment of Severe Recurrent Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) (Phase II)- IT
Fondazione IRCCS Policlinico San Matteo
Clinica Medica III

Gelderland
NIJMEGEN
An Uncontrolled, Pilot-study Assessing the Efficacy of Octreotide Long-acting Release to Decrease Transfusion Requirements and Endoscopy Frequency in Patients With Rendu-Osler-Weber and Gastrointestinal Bleeding
Radboudumc - Radboud universitair medisch centrum
Afdeling Maag-, Darm- en Leverziekten

WIEN
WIEN

Prospective, Multicenter, Single-arm Study to Assess the Safety and Performance of the BeGrow Stent System in Newborns and Infants to Treat Pulmonary Artery Stenosis - AT
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Pädiatrische Kardiologie - Kinderherzzentrum Wien
Ensaio (s) clínico (s) multinacional (ais)

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS
VASE: Phase III multicentric study evaluating the efficacy and safety of sirolimus in Vascular Anomalies that are refractory to standard care
Cliniques universitaires Saint-Luc - UCLouvain
Centre des Malformations Vasculaires

ARRONDISSEMENT BRUSSELS-CAPITAL
ADDRESS: NOT PROVIDED - BE
ANITA: A Phase II Multicenter Study Comparing the Efficacy of the Oral Angiogenesis Inhibitor Nintedanib With the Intravenous Cytotoxic Compound Ifosfamide for Treatment of Patients With Advanced Metastatic Soft Tissue Sarcoma After Failure of Systemic Non-oxazaphosporine-based First Line Chemotherapy for Inoperable Disease
Institution: Information not provided - BE

Cataluña
ST QUINTÍ DE MEDIONA

New York
NEW YORK
A randomized Phase 3, multicenter, Open-Label Study comparing TH-302 in Combination with Doxorubicin vs. Doxorubicin alone in subjects with locally advanced unresectable or metastatic soft tissue sarcoma - coordination
Memorial Sloan-Kettering Cancer Center
Department of Medicine Melanoma and Sarcoma Service

Washington
ADDRESS: NOT PROVIDED - US
ANNOUNCE 2: A Phase 1b (Open-Label) / Phase 2 (Randomized,Double-Blinded) Study Evaluating Gemcitabine andDocetaxel With or Without Olaratumab in the Treatment ofAdvanced Soft Tissue Sarcoma
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US