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Ensaio (s) clínico (s) nacional (is)
ALEMANHA
Baden-Württemberg
MANNHEIM
INVICTUS: A Phase 3, INterVentional, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of DCC-2618 In Patients with AdvanCed Gastrointestinal Stromal TUmorS who have Received Treatment with Prior Anticancer Therapies -DE-
Universitätsmedizin Mannheim
Sarkom-Zentrum
ALEMANHA
Berlin
ADDRESS: NOT PROVIDED - DE
PAGIST- Pazopanib in advanced gastrointestinal stromal tumors refractory to imatinib and sunitinib. A non-comparative phase II multicenter study by the Scandinavian Sarcoma Group -DE-
Institution: Information not provided - DE
ALEMANHA
Brandenburg
BAD SAAROW
INVICTUS: A Phase 3, INterVentional, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of DCC-2618 In Patients with AdvanCed Gastrointestinal Stromal TUmorS who have Received Treatment with Prior Anticancer Therapies -DE-
HELIOS Klinikum Bad Saarow
Sarkomzentrum Berlin-Brandenburg
ALEMANHA
Nordrhein-Westfalen
ESSEN
POETIG: Phase 2 Trial of Ponatinib in Patients with Metastatic and/or Unresectable Gastrointestinal Stromal Tumor (GIST) Following Failure or Intolerance of Prior Therapy with Imatinib - DE
Westdeutsches Tumorzentrum Essen (WTZ)
Klinik für Innere Medizin (Tumorforschung)
ALEMANHA
Nordrhein-Westfalen
ESSEN
INVICTUS: A Phase 3, INterVentional, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of DCC-2618 In Patients with AdvanCed Gastrointestinal Stromal TUmorS who have Received Treatment with Prior Anticancer Therapies -DE-
Westdeutsches Tumorzentrum Essen (WTZ)
Klinik für Innere Medizin (Tumorforschung)
AUSTRIA
WIEN
ADDRESS: NOT PROVIDED - AT
GRID: A Randomized, Double-blind, Placebo-controlled Phase III Study of Regorafenib Plus Best Supportive Care Versus Placebo Plus Best Supportive Care for Subjects With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (GIST) Whose Disease Has Progressed Despite Prior Treatment With at Least Imatinib and Sunitinib - AT
Institution: Information not provided - AT
AUSTRIA
WIEN
ADDRESS: NOT PROVIDED - AT
A Prospective, Multicenter, Randomized, Open-label, Active-controlled, Two-parallel Groups, Phase 3 Study to Compare the Efficacy and Safety of Masitinib to Sunitinib in Patients With Gastrointestinal Stromal Tumor After Progression With Imatinib at 400mg as First Line Treatment - AT
Institution: Information not provided - AT
AUSTRIA
WIEN
WIEN
A Multicenter Phase 1, Open-Label Study of DCC-2618 to Assess Safety, Tolerability, and Pharmacokinetics in Patients With Advanced Malignancies - AT
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Hämatologie und Hämostaseologie
AUSTRIA
WIEN
WIEN
Three Versus Five Years of Adjuvant Imatinib as Treatment of Patients With Operable GIST With a High Risk for Recurrence: A Randomised Phase III Study - AT
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Onkologie
AUSTRIA
WIEN
WIEN
An Open Label, Multi-center Nilotinib Roll-over Protocol for Patients Who Have Completed a Previous Novartis-sponsored Nilotinib Study and Are Judged by the Investigator to Benefit From Continued Nilotinib Treatment (Phase IV) - AT
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Onkologie
AUSTRIA
WIEN
WIEN
A Phase II, Open-label, Study in Subjects With BRAF V600E-Mutated Rare Cancers With Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib - AT
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Onkologie
AUSTRIA
WIEN
WIEN
VOYAGER: An International, Multicenter, Open-label, Randomized, Phase 3 Study of BLU-285 vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic Gastrointestinal Stromal Tumor (GIST) - AT
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Onkologie
BELGICA
VLAAMS BRABANT
LEUVEN
INVICTUS: A Phase 3, INterVentional, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of DCC-2618 In Patients with AdvanCed Gastrointestinal Stromal TUmorS who have Received Treatment with Prior Anticancer Therapies - BE
UZ Leuven - Campus Gasthuisberg
Dienst maag-, darm- en leverziekten (gastro-enterologie en hepatologie)
ESPANHA
Cataluña
BADALONA
Three Versus Five Years of Adjuvant Imatinib as Treatment of Patients With Operable GIST With a High Risk for Recurrence: A Randomised Phase III Study - ES
ICO Badalona - Hospital Germans Trias i Pujol
Servicio de Oncología Médica
ESPANHA
Cataluña
BARCELONA
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Trial of Crenolanib in Subjects with Advanced or Metastatic Gastrointestinal Stromal Tumors with a D842V Mutation in the PDGFRA Gene - ES
Hospital Universitari Vall d'Hebron
Servicio de Oncología Médica
ESPANHA
Cataluña
BARCELONA
A Phase II, Open-label, Study in Subjects With BRAF V600E-Mutated Rare Cancers With Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib - ES
Hospital Universitari Vall d'Hebron
Servicio de Oncología Médica
ESPANHA
Cataluña
BARCELONA
SeliGIST: A multicenter, phase Ib/II trial of selinexor in combination with imatinib in patients with metastatic and/or unresectable gastrointestinal stromal tumors (GISTs) - ES
Hospital Universitari Vall d'Hebron
Servicio de Oncología Médica
ESPANHA
Madrid
ADDRESS: NOT PROVIDED - ES
An Open Label, Multi-center Nilotinib Roll-over Protocol for Patients Who Have Completed a Previous Novartis-sponsored Nilotinib Study and Are Judged by the Investigator to Benefit From Continued Nilotinib Treatment (Phase IV) - ES
Institution: Information not provided - ES
ESPANHA
Madrid
ADDRESS: NOT PROVIDED - ES
INVICTUS: A Phase 3, INterVentional, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of DCC-2618 In Patients with AdvanCed Gastrointestinal Stromal TUmorS who have Received Treatment with Prior Anticancer Therapies - ES
Institution: Information not provided - ES
ESPANHA
Madrid
ADDRESS: NOT PROVIDED - ES
Intrigue: A Phase 3, Interventional, Randomized, Multicenter, Open-Label Study of DCC-2618 vs Sunitinib in Patients with Advanced Gastrointestinal Stromal Tumors after Treatment with Imatinib - ES
Institution: Information not provided - ES
ESPANHA
Madrid
ADDRESS: NOT PROVIDED - ES
VOYAGER: An International, Multicenter, Open-label, Randomized, Phase 3 Study of BLU-285 vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic Gastrointestinal Stromal Tumor (GIST) - ES
Institution: Information not provided - ES
ESPANHA
Madrid
MADRID
REGISTRI: Phase II, single arm, non-randomized and multicenter clinical trial of regorafenib as a single agent in the first-line setting for patients with metastatic and/or unresectable KIT/PDGFR Wild Type GIST - ES
GEIS - Grupo Español de Investigación de Sarcomas
ESPANHA
Madrid
MADRID
A Phase II, Open-label, Study in Subjects With BRAF V600E-Mutated Rare Cancers With Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib - ES
Hospital Universitario 12 de Octubre
Servicio de Oncología Médica
ESPANHA
Navarra
PAMPLONA
A Phase II, Open-label, Study in Subjects With BRAF V600E-Mutated Rare Cancers With Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib - ES
Clínica Universidad de Navarra
Servicio de Oncología Médica
ESTADOS UNIDOS
Washington
ADDRESS: NOT PROVIDED - US
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Trial of Crenolanib in Subjects with Advanced or Metastatic Gastrointestinal Stromal Tumors with a D842V Mutation in the PDGFRA Gene. -GB
Institution: Information not provided - US
FRANCA
AUVERGNE-RHONE-ALPES
ADDRESS: NOT PROVIDED - FR
GRID: A randomized, double-blind, placebo-controlled phase III study of regorafenib plus best supportive care versus placebo plus best supportive care for subjects with metastatic and/or unresectable gastrointestinal stromal tumors (GIST) whose disease has progressed despite prior treatment with at least imatinib and sunitinib - FR
Institution: Information not provided - FR
FRANCA
AUVERGNE-RHONE-ALPES
ADDRESS: NOT PROVIDED - FR
A Dose-finding Phase Ib Multicenter Study of Imatinib in Combination With the Oral Phosphatidyl-inositol 3-kinase (PI3K) Inhibitor BYL719 in Patients With Gastrointestinal Stromal Tumor (GIST) Who Failed Prior Therapy With Imatinib and Sunitinib - FR
Institution: Information not provided - FR
FRANCA
AUVERGNE-RHONE-ALPES
ADDRESS: NOT PROVIDED - FR
Phase II Study of Cabozantinib in Patients With Gastrointestinal Stromal Tumor (GIST) Who Progressed During Neoadjuvant, Adjuvant or Palliative Therapy With Imatinib and Sunitinib - FR
Institution: Information not provided - FR
FRANCA
AUVERGNE-RHONE-ALPES
LYON
ImadGist : A Randomized Multicenter Phase III Trial Evaluating the Interest of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST)
CLCC Léon Bérard
Cancérologie médicale - Sarcomes et GIST, Tumeurs rares
FRANCA
HAUTS-DE-FRANCE
LILLE
A prospective, multicenter, randomized, open-label, active-controlled, phase III study to compare efficacy and safety of masitinib to imatinib at 400 or 600 mg in treatment of patients with gastro-intestinal stromal tumour in first line medical treatmen - FR
CLCC Oscar Lambret
Département de cancérologie générale
FRANCA
HAUTS-DE-FRANCE
LILLE
A prospective, multicenter, randomized, open-label, active-controlled, 2-parallel group, phase III study to compare efficacy and safety of masitinib at 7.5 mg/kg/day to imatinib at 400 or 600 mg in treatment of patients with gastro-intestinal stromal tumour in first line medical treatment - BE
CLCC Oscar Lambret
Département de cancérologie générale
FRANCA
ILE-DE-FRANCE
VILLEJUIF
Phase II Study of Oral AB1010 (Masitinib) in Non Pre-treated, Inoperable Patients With Locally Advanced/Metastatic Gastro-intestinal Stromal Tumour (GIST)
CLCC Institut Gustave Roussy
Département de Médecine oncologique - Sarcomes
FRANCA
NOUVELLE AQUITAINE
BORDEAUX
CYCLIGIST: Efficacy and Safety of PD-0332991 in Patients With Advanced Gastrointestinal Stromal Tumors Refractory to Imatinib and Sunitinib: A Phase 2 Study
CLCC Institut Bergonié
Département d'oncologie médicale - Sarcomes
FRANCA
NOUVELLE AQUITAINE
BORDEAUX
ALT GIST: A Randomised Phase II Trial of Imatinib Alternating With Regorafenib Compared to Imatinib Alone for the First Line Treatment of Advanced Gastrointestinal Stromal Tumour (GIST) - FR
CLCC Institut Bergonié
Département d'oncologie médicale - Sarcomes
FRANCA
NOUVELLE AQUITAINE
PESSAC
An Open Label, Multi-center Imatinib Roll-over Protocol for Patients Who Have Completed a Previous Novartis-sponsored Imatinib Study and Are Judged by the Investigator to Benefit From Continued Imatinib Treatment - FR
CHU de Bordeaux-GH Sud - Hôpital Haut-Lévêque
Service d'hématologie et thérapie cellulaire
ITALIA
PUGLIA
SAN GIOVANNI ROTONDO
Randomized study in open at active control of IIIb phase, of Sunitinib vs Imatinib in the treatment of patients with metastasized gastrointestinal tumor whose disease is evolved under treatment of Imatinib
Fondazione IRCCS Ospedale Casa Sollievo della Sofferenza
U.O. di Oncologia
REINO UNIDO
Cambridgeshire
CAMBRIDGE
CAMN107A2409: An Open Label, Multi-center Nilotinib Roll-over Protocol for Patients Who Have Completed a Previous Novartis-sponsored Nilotinib Study and Are Judged by the Investigator to Benefit From Continued Nilotinib Treatment (Phase IV) - UK
Addenbrooke's Hospital
Addenbrookes Hospital
REINO UNIDO
Greater London
LONDON
CAMN107A2409: An Open Label, Multi-center Nilotinib Roll-over Protocol for Patients Who Have Completed a Previous Novartis-sponsored Nilotinib Study and Are Judged by the Investigator to Benefit From Continued Nilotinib Treatment (Phase IV) - UK
Royal Marsden Hospital
Section of Medicine
REINO UNIDO
Greater Manchester
ADDRESS: NOT PROVIDED - UK
A Phase 1 Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid Tumors
Institution: Information not provided - UK
SUICA
Suisse Romande
ADDRESS: NOT PROVIDED - CH
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Trial of Crenolanib in Subjects with Advanced or Metastatic Gastrointestinal Stromal Tumors with a D842V Mutation in the PDGFRA Gene (Phase III) - CH
Institution: Information not provided - CH
BELGICA
ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS
STEP: Sorafenib Long Term Extension Program - BE
Cliniques universitaires Saint-Luc - UCLouvain
Pneumologie_Oncologie thoracique
Ensaio (s) clínico (s) multinacional (ais)
BELGICA
ARRONDISSEMENT BRUSSELS-CAPITAL
ADDRESS: NOT PROVIDED - BE
Phase II Study of Cabozantinib in Patients With Gastrointestinal Stromal Tumor (GIST) Who Progressed During Neoadjuvant, Adjuvant or Palliative Therapy With Imatinib and Sunitinib
Institution: Information not provided - BE
ESTADOS UNIDOS
Kansas
LAWRENCE
A Multicenter Phase 1, Open-Label Study of DCC-2618 to Assess Safety, Tolerability, and Pharmacokinetics in Patients With Advanced Malignancies
Deciphera Pharmaceuticals, LLC.
ESTADOS UNIDOS
Massachusetts
CAMBRIDGE
NAVIGATOR: A Phase 1 Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid Tumors
Blueprint Medicines Corporation
ESTADOS UNIDOS
Texas
DALLAS
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Trial of Crenolanib in Subjects with Advanced or Metastatic Gastrointestinal Stromal Tumors with a D842V Mutation in the PDGFRA Gene.
Arog Pharmaceuticals, Inc.
FRANCA
ILE-DE-FRANCE
PARIS