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39 Ergebnis(se)

Forschungsprojekt(e)

Role of the Coiled-coil structure of the Huntingtin protein in the intercellular propagation of polyQ aggregates and in the progression of the disease Institution: Information not provided - IT

Regulation of skeletal muscle mass by a novel muscle-specific alternative splicing isoform of the mitochondrial calcium uniporter activator MICU1 Institution: Information not provided - IT

Dissecting the retrograde signalling that controls neuromuscular Junction Institution: Information not provided - IT

Functional assessment of skeletal muscle beta2-adrenoceptor modulation by the catecholaminergic component of motor nerves, explored using in vivo optogenetics and multiphoton imaging Institution: Information not provided - IT

Bone phenotype in Duchenne muscular dystrophy: unveiling the role of LCN2 and implications for therapy. Institution: Information not provided - IT

Establishing new models for primary dystroglycanopathies Institution: Information not provided - IT

PGC1 alpha gene expression regulation and Mitochondrial Biogenesis impairment in Muscular Dystrophies: new molecular signatures for novel therapeutic strategy Institution: Information not provided - IT

Misglycosylation in Charcot-Marie-Tooth neuropathies associated to MPZ mutations Institution: Information not provided - IT

Strategies to enhance the efficacy of enzyme replacement and gene therapy in Pompe disease Institution: Information not provided - IT

Pre-clinical evaluation of tamoxifen in mouse models of X-linked centronuclear myopathy and other severe muscular diseases Institution: Information not provided - IT

Role of PTX3 in the pathogenesis of idiopathic inflammatory myopathies Institution: Information not provided - IT

Pin1: a new potential target to induce slow fiber conversion in Duchenne Muscular Dystrophy Institution: Information not provided - IT

Immune system involvement in DMD pathology: the role of the immunoproteasome and its therapeutic potential. Institution: Information not provided - IT

Study of the multiple functions of Nfix in Muscular Dystrophies: a focus on macrophage biology Institution: Information not provided - IT

Therapeutic relevance of the sphingolipid-metabolizing enzyme acid sphingomyelinase as a new pathogenetic factor in Duchenne muscular dystrophy Institution: Information not provided - IT

A Long-Term Retrospective and Prospective Safety Study of Arsenic Trioxide in Patients With Newly Diagnosed, Low- to Intermediate-Risk Acute Promyelocytic Leukemia (APL) Institution: Information not provided - IT

Development of a small-molecule therapy for PH1 based on the combined administration of B6 vitamers and pharmacological chaperones Institution: Information not provided - IT

Multizentrische Forschungsprojekte

TRANSCAN-2: Aligning national/regional translational cancer research programmes and activities European Commission DG Research - Directorate General for Research

DRAMA: Defeating Recurrence and resistance in AML: Multigenomic Approaches to analyse heterogeneity European Commission DG Research - Directorate General for Research

HEPAMUT: Mutated neo-antigens in hepatocellular carcinoma European Commission DG Research - Directorate General for Research

REVOLUTION: Prediction of Nivolumab action in metastatic renal cancer patients: Treg function, tumoral access and NK interaction as predictive biomarkers of immunotherapy European Commission DG Research - Directorate General for Research

CLEARLY: Validation of multiparametric models and Circulating and imaging biomarkers to improve Lung cancer EARLY detection European Commission DG Research - Directorate General for Research

HLALOSS: New technologies for early detection of HLA loss leukemia relapse after allogeneic hematopoietic stem cell transplantation, and identification of relevant risk factors. European Commission DG Research - Directorate General for Research

HAPLO-IMMUNE: Validation of immune biomarkers predictive of clinical outcome after HLA-haploidentical hematopoietic stem cell transplantation for acute leukemia European Commission DG Research - Directorate General for Research

Euro MDS: An integrated European platform to conduct translational studies in myelodysplastic syndromes based on the EuroBloodNet infrastructure European Commission DG Research - Directorate General for Research

TOPMESO: A TranslatiOnal Platform for de-orphaning malignant pleural MESOthelioma European Commission DG Research - Directorate General for Research

ARREST: Approaching recurrence and resistance mechanisms in esophagogastric adenocarcinomas from the prospective MEMORI trial European Commission DG Research - Directorate General for Research

TRANSCAN-2: Aligning national/regional translational cancer research programmes and activities Institution: Information not provided - IT

DRAMA: Defeating Recurrence and resistance in AML: Multigenomic Approaches to analyse heterogeneity Institution: Information not provided - IT

HEPAMUT: Mutated neo-antigens in hepatocellular carcinoma Institution: Information not provided - IT

REVOLUTION: Prediction of Nivolumab action in metastatic renal cancer patients: Treg function, tumoral access and NK interaction as predictive biomarkers of immunotherapy Institution: Information not provided - IT

CLEARLY: Validation of multiparametric models and Circulating and imaging biomarkers to improve Lung cancer EARLY detection Institution: Information not provided - IT

HLALOSS: New technologies for early detection of HLA loss leukemia relapse after allogeneic hematopoietic stem cell transplantation, and identification of relevant risk factors. Institution: Information not provided - IT

HAPLO-IMMUNE: Validation of immune biomarkers predictive of clinical outcome after HLA-haploidentical hematopoietic stem cell transplantation for acute leukemia Institution: Information not provided - IT

Euro MDS: An integrated European platform to conduct translational studies in myelodysplastic syndromes based on the EuroBloodNet infrastructure Institution: Information not provided - IT

TOPMESO: A TranslatiOnal Platform for de-orphaning malignant pleural MESOthelioma Institution: Information not provided - IT

ARREST: Approaching recurrence and resistance mechanisms in esophagogastric adenocarcinomas from the prospective MEMORI trial Institution: Information not provided - IT

EDSCIDPROG: Gene edited lymphoid progenitors for adoptive transfer as a treatment of primary Immunodeficiency Institution: Information not provided - IT

EDSCIDPROG: Gene edited lymphoid progenitors for adoptive transfer as a treatment of primary Immunodeficiency ISS - Istituto Superiore di Sanità ERA-Net for research programs on rare diseases - Italy

Role of the Coiled-coil structure of the Huntingtin protein in the intercellular propagation of polyQ aggregates and in the progression of the disease
Institution: Information not provided - IT

Regulation of skeletal muscle mass by a novel muscle-specific alternative splicing isoform of the mitochondrial calcium uniporter activator MICU1
Institution: Information not provided - IT

Dissecting the retrograde signalling that controls neuromuscular Junction
Institution: Information not provided - IT

Functional assessment of skeletal muscle beta2-adrenoceptor modulation by the catecholaminergic component of motor nerves, explored using in vivo optogenetics and multiphoton imaging
Institution: Information not provided - IT

Bone phenotype in Duchenne muscular dystrophy: unveiling the role of LCN2 and implications for therapy.
Institution: Information not provided - IT

Establishing new models for primary dystroglycanopathies
Institution: Information not provided - IT

PGC1 alpha gene expression regulation and Mitochondrial Biogenesis impairment in Muscular Dystrophies: new molecular signatures for novel therapeutic strategy
Institution: Information not provided - IT

Misglycosylation in Charcot-Marie-Tooth neuropathies associated to MPZ mutations
Institution: Information not provided - IT

Strategies to enhance the efficacy of enzyme replacement and gene therapy in Pompe disease
Institution: Information not provided - IT

Pre-clinical evaluation of tamoxifen in mouse models of X-linked centronuclear myopathy and other severe muscular diseases
Institution: Information not provided - IT

Role of PTX3 in the pathogenesis of idiopathic inflammatory myopathies
Institution: Information not provided - IT

Pin1: a new potential target to induce slow fiber conversion in Duchenne Muscular Dystrophy
Institution: Information not provided - IT

Immune system involvement in DMD pathology: the role of the immunoproteasome and its therapeutic potential.
Institution: Information not provided - IT

Study of the multiple functions of Nfix in Muscular Dystrophies: a focus on macrophage biology
Institution: Information not provided - IT

Therapeutic relevance of the sphingolipid-metabolizing enzyme acid sphingomyelinase as a new pathogenetic factor in Duchenne muscular dystrophy
Institution: Information not provided - IT

A Long-Term Retrospective and Prospective Safety Study of Arsenic Trioxide in Patients With Newly Diagnosed, Low- to Intermediate-Risk Acute Promyelocytic Leukemia (APL)
Institution: Information not provided - IT

Development of a small-molecule therapy for PH1 based on the combined administration of B6 vitamers and pharmacological chaperones
Institution: Information not provided - IT

TRANSCAN-2: Aligning national/regional translational cancer research programmes and activities

European Commission

DG Research - Directorate General for Research

DRAMA: Defeating Recurrence and resistance in AML: Multigenomic Approaches to analyse heterogeneity

European Commission

DG Research - Directorate General for Research

HEPAMUT: Mutated neo-antigens in hepatocellular carcinoma

European Commission

DG Research - Directorate General for Research

REVOLUTION: Prediction of Nivolumab action in metastatic renal cancer patients: Treg function, tumoral access and NK interaction as predictive biomarkers of immunotherapy

European Commission

DG Research - Directorate General for Research

CLEARLY: Validation of multiparametric models and Circulating and imaging biomarkers to improve Lung cancer EARLY detection

European Commission

DG Research - Directorate General for Research

HLALOSS: New technologies for early detection of HLA loss leukemia relapse after allogeneic hematopoietic stem cell transplantation, and identification of relevant risk factors.

European Commission

DG Research - Directorate General for Research

HAPLO-IMMUNE: Validation of immune biomarkers predictive of clinical outcome after HLA-haploidentical hematopoietic stem cell transplantation for acute leukemia

European Commission

DG Research - Directorate General for Research

Euro MDS: An integrated European platform to conduct translational studies in myelodysplastic syndromes based on the EuroBloodNet infrastructure

European Commission

DG Research - Directorate General for Research

TOPMESO: A TranslatiOnal Platform for de-orphaning malignant pleural MESOthelioma

European Commission

DG Research - Directorate General for Research

ARREST: Approaching recurrence and resistance mechanisms in esophagogastric adenocarcinomas from the prospective MEMORI trial

European Commission

DG Research - Directorate General for Research

TRANSCAN-2: Aligning national/regional translational cancer research programmes and activities

Institution: Information not provided - IT

DRAMA: Defeating Recurrence and resistance in AML: Multigenomic Approaches to analyse heterogeneity

Institution: Information not provided - IT

HEPAMUT: Mutated neo-antigens in hepatocellular carcinoma

Institution: Information not provided - IT

REVOLUTION: Prediction of Nivolumab action in metastatic renal cancer patients: Treg function, tumoral access and NK interaction as predictive biomarkers of immunotherapy

Institution: Information not provided - IT

CLEARLY: Validation of multiparametric models and Circulating and imaging biomarkers to improve Lung cancer EARLY detection

Institution: Information not provided - IT

HLALOSS: New technologies for early detection of HLA loss leukemia relapse after allogeneic hematopoietic stem cell transplantation, and identification of relevant risk factors.

Institution: Information not provided - IT

HAPLO-IMMUNE: Validation of immune biomarkers predictive of clinical outcome after HLA-haploidentical hematopoietic stem cell transplantation for acute leukemia

Institution: Information not provided - IT

Euro MDS: An integrated European platform to conduct translational studies in myelodysplastic syndromes based on the EuroBloodNet infrastructure

Institution: Information not provided - IT

TOPMESO: A TranslatiOnal Platform for de-orphaning malignant pleural MESOthelioma

Institution: Information not provided - IT

ARREST: Approaching recurrence and resistance mechanisms in esophagogastric adenocarcinomas from the prospective MEMORI trial

Institution: Information not provided - IT

EDSCIDPROG: Gene edited lymphoid progenitors for adoptive transfer as a treatment of primary Immunodeficiency

Institution: Information not provided - IT

EDSCIDPROG: Gene edited lymphoid progenitors for adoptive transfer as a treatment of primary Immunodeficiency

ISS - Istituto Superiore di Sanità

ERA-Net for research programs on rare diseases - Italy