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Research projects

Andalucía
SEVILLA
Development of new cannabiotic-based compound for the treatment of multiple myeloma, acute myeloblastic leukemia and related conditions
Hospital Universitario Virgen del Rocío
FISEVI - Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

NIEDERÖSTERREICH
KREMS AN DER DONAU
STAT3 isoforms in acute myeloid leukemia
Karl Landsteiner Privatuniversität für Gesundheitswissenschaften
Fachbereich Pharmakologie

OBERÖSTERREICH
LINZ
AMLSG BiO: Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms, and Higher Risk Myelodysplastic Syndrome - The Biology and Outcome (BiO)-Project - AT
Ordensklinikum Linz GmbH Barmherzige Schwestern
Interne I - Internistische Onkologie, Hämatologie u. Gastroenterologie

STEIERMARK
GRAZ
Subclonal TP53 mutations in acute myeloid leukemia
Medizinische Universität Graz
Klinische Abteilung für Hämatologie

WIEN
ADDRESS: NOT PROVIDED - AT
HARMONY: Healthcare Alliance for Resourceful Medicines Offensive against Neoplasms in HematologY - AT
Institution: Information not provided - AT

WIEN
ADDRESS: NOT PROVIDED - AT
BIMI: Multicenter Case-control Study of Breakthrough Invasive Mold Infections Under Posaconazole Prophylaxis - AT
Institution: Information not provided - AT

WIEN
WIEN
Find tumor immune evasion strategies by cellular barcoding
St. Anna Kinderkrebsforschung
Children's Cancer Research Institute

WIEN
WIEN
CLOSER - Childhood Leukemia: Overcoming distance between South America and Europe Regions - AT
St. Anna Kinderkrebsforschung

WIEN
WIEN
Linking CDK6 to the epigenome in AML (acute myeloid leukemia)
Veterinärmedizinische Universität Wien
Institut für Pharmakologie und Toxikologie

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS
MicroAML: Investigation of the Gut Microbiota in Patients With Acute Myeloid Leukemia
Metabolism & Nutrition (MNut), Louvain Drug Institute
Metabolism & Nutrition

Ontario
TORONTO
CD123-Targeted Auger Electron Radioimmunotherapy of Acute Myelogenous Leukemia (AML)
University of Toronto
Leslie Dan Faculty of Pharmacy, University of Toronto

Baden-Württemberg
FREIBURG
The role of the histone demethylase LSD1 in the pathogenesis of AM (FOR 2674: Aging-related epigenetic remodeling in acute myeloid leukemia)
Zentrum für Klinische Forschung am Universitätsklinikum Freiburg
Sektion Molekulare Hämatologie

Baden-Württemberg
HEIDELBERG
INFORM-Registry: INdividualized Therapy FOr Relapsed Malignancies in Childhood
Deutsches Krebsforschungszentrum
Klinische Kooperationseinheit Pädiatrische Onkologie

Baden-Württemberg
ULM
'Dissection of the function of the ''Lymphoid enhancer-binding factor 1'' (Lef1) in acute myeloid leukemia (SFB 1074: Experimental Models and Clinical Translation in Leukemia9'
Universitätsklinikum Ulm
Institut für Experimentelle Tumorforschung

Baden-Württemberg
ULM
Deciphering Critical Changes in the Methylome of Hematopoietic Stem Cells in Age-related Clonal Hematopoiesis and Myeloid Leukemogenesis (FOR 2674: Aging-related epigenetic remodeling in acute myeloid leukemia)
Universitätsklinikum Ulm
Institut für Experimentelle Tumorforschung

Baden-Württemberg
ULM
AMLSG BIO: Registry Study on Patient Characteristics, Biolo gical Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms, and Higher Risk Myelodysplastic Syndrome - The Biology and Outcome (BiO)-Project
Universitätsklinikum Ulm am Oberen Eselsberg
Klinik für Innere Medizin III

Niedersachsen
HANNOVER
AML-BFM Register 2017: Clinical registry for children and adolescents with acute myeloid leukemia
KPOH Geschäftsführung Hannover
Kompetenznetz Pädiatrische Onkologie und Hämatologie

Nordrhein-Westfalen
BONN
'Dissection of the function of the ''Lymphoid enhancer-binding factor 1'' (Lef1) in acute myeloid leukemia (SFB 1074: Experimental Models and Clinical Translation in Leukemia9'
Deutsche Forschungsgemeinschaft

Nordrhein-Westfalen
ESSEN
AML-BFM Register 2017: Clinical registry for children and adolescents with acute myeloid leukemia
Universitätsklinikum Essen
Klinik für Kinderheilkunde III - Abteilung für pädiatrische Hämatologie und Onkologie

EMILIA ROMAGNA
MELDOLA
Integrated Multiomics and Multilevel Characterization of Haematological Disorders and Malignancies
IRST - Istituto Scientifico Romagnolo per lo studio e la cura dei Tumori
IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori

Andalucía
GRANADA
A multiOMICS approach to characterize de novo and secondary acute myeloid leukaemia: a study in the context of the NuCLEAR consortium and the GESMD cooperative group
Fundación para la Investigación Biosanitaria de Andalucía Oriental
FIBAO: Fundación para la Investigación Biosanitaria de Andalucía Oriental Alejando Otero

Cataluña
BARCELONA
New approaches to WT1 analysis in myeloid malignancies. Utility of single-cell studies
IIB Sant Pau - Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Cataluña
BARCELONA
Subclonal AML populations and leukemia stem cell compartment identified using single cell RNA-sequencing and multiparameter flow cytometry: Relevance for response to therapy
IIB Sant Pau - Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Comunidad Valenciana
VALENCIA
Developing a Molecular Diagnostic Platform for Personalized Medicine for Acute Myeloid Leukemia
Hospital Universitario y Politécnico La Fe
Servicio de Hematología y Hemoterapia

Navarra
PAMPLONA
Transcriptional and gene regulatory networks in acute myeloid leukemia secondary to myelodysplastic syndromes: identification of novel therapeutic targets
CIMA - Centro de Investigación Médica Aplicada
Grupo de Patología Mieloide

Navarra
PAMPLONA
Differentiation therapy strategy using novel epigenetic inhibitors for acute myeloid leukemia
IdiSNA - Instituto de Investigación Sanitaria de Navarra
Instituto de Investigación Sanitaria de Navarra

Navarra
PAMPLONA
Mechanisms and antileukemic efficacy of combination therapies based on functional PP2A activation in acute myeloid leukemia. Role of the regulatory subunits of PP2A as specific targets
IdiSNA - Instituto de Investigación Sanitaria de Navarra
Instituto de Investigación Sanitaria de Navarra

Region Stockholm
HUDDINGE
Molecular pathogenesis in myelodysplastic syndromes and acute myeloid leukemia
Karolinska Institutet - Huddinge
Department of Medicine, Huddinge (MedH)

Region Stockholm
STOCKHOLM
Study of chemotherapy resistance and DNA methylation in acute myeloid leukemia samples
Karolinska Universitetssjukhuset - Huddinge
Hematology Centre

Suisse Alémanique
BASEL
Characterization of resistance to tyrosine kinase inhibition as a basis for novel therapeutic approaches in myeloid malignancies
Universitätsspital Basel
Departement Biomedizin

Suisse Alémanique
BASEL
Modeling for targeting of acute myeloid leukemia driven by epigenetic mechanisms
Universitätsspital Basel
Departement Biomedizin

Suisse Alémanique
BERN
Targeting Immune Checkpoints to Eliminate Leukemia Stem Cells
Inselspital Universitätsspital
Universitätsklinik für Medizinische Onkologie

Greater London
SURREY
Assessing Feasibility of Expansion and Characterization of Gamma Delta T Cells From Peripheral Blood and Bone Marrow of Patients With Acute Myeloid Leukaemia as Starting Product for Generation of CD33-CD28 Gamma Delta T Cells-GB
The Royal Marsden
Royal Marsden NHS Foundation Trust

Washington
ADDRESS: NOT PROVIDED - US
Therapeutics for rare and neglected diseases - science
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US
The development of multikinase inhibitors for the treatment of selected cancers
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US
Mechanistic and translational studies of cbf leukemia
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US
Molecular pathogenesis of chromosome 16 inversion in human leukemia
Institution: Information not provided - US

Baden-Württemberg
FREIBURG
MyPred: Optimizing the Care of Young Individuals with Predisposition to Myeloid Neoplasia
Zentrum für Kinder- und Jugendmedizin Freiburg
Klinik für Pädiatrische Hämatologie und Onkologie

Baden-Württemberg
TÜBINGEN
MyPred: Optimizing the Care of Young Individuals with Predisposition to Myeloid Neoplasia
Department für Innere Medizin - Medizinische Universitätsklinik Tübingen
Innere Medizin II - Onkologie, Hämatologie, Klinische Immunologie, Rheumatologie und Pulmologie

Hessen
FRANKFURT AM MAIN
MyPred: Optimizing the Care of Young Individuals with Predisposition to Myeloid Neoplasia
Universitätsklinikum Frankfurt
Schwerpunkt Onkologie, Hämatologie und Hämostaseologie

Niedersachsen
HANNOVER
MyPred: Optimizing the Care of Young Individuals with Predisposition to Myeloid Neoplasia
Medizinische Hochschule Hannover
Institut für Humangenetik

Nordrhein-Westfalen
DÜSSELDORF
MyPred: Optimizing the Care of Young Individuals with Predisposition to Myeloid Neoplasia
Universitätsklinikum Düsseldorf
Klinik für Kinder-Onkologie, -Hämatologie und klinische Immunologie

Suisse Alémanique
BERN
Exploiting metabolic liabilities in leukemic stem cells for targeted therapy of myeloid malignancies
Universitätsspital Inselspital
Universitätsklinik für Hämatologie und Hämatologisches Zentrallabor (UKH-HZL)

WIEN
ADDRESS: NOT PROVIDED - AT
A Quality Improvement Project to Implement Psychosocial Care Standards in Clinical Practice in Pediatric Oncology "My Logbook! - I Know my Way Around!" Development and Evaluation of a Consensus and Evidence Based Psychosocial Therapy Tool in a Preliminary Psychosocial Study on Therapy Optimization - AT
Institution: Information not provided - AT

WIEN
WIEN
PanCareSurPass: PanCare studies of the scale-up and implementation of the digital Survivorship Passport to improve people-centred care for childhood cancer survivors - AT
Gesundheit Österreich GmbH

WIEN
WIEN
Christian Doppler Laboratory for Next Generation CAR-T Cells
St. Anna Kinderkrebsforschung
Children's Cancer Research Institute

WIEN
WIEN
Instand-NGS4P: Integrated and standardized NGS workflows for Personalised therapy - AT
St. Anna Kinderkrebsforschung

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS
Follow-up of Fertility in Young Adults Who Did or Did Not Store Testicular Tissue Before Gonadotoxic Treatment for Fertility Preservation
Universitair Ziekenhuis Brussel
Universitair Ziekenhuis Brussel (UZ Brussel)

Ontario
TORONTO
Beyond the Genome: Transcriptome Based Diagnostics for Rare Diseases and Cancer
Hospital for Sick Children, Research Institute

Baden-Württemberg
HEIDELBERG
ERA-NET TRANSCAN: BRCAddict - BRCAness as a therapeutic target for solid high-risk childhood tumors
Deutsches Krebsforschungszentrum
KITZ - Hopp-Kindertumorzentrum Heidelberg

VENETO
PADOVA
Modulating BMP axis to prevent muscle loss, dismantling of NMJ and denervation in cancer cachexia
Venetian Institute of Molecular Medicine
Fondazione per la ricerca Biomedica avanzata ONLUS

Washington
ADDRESS: NOT PROVIDED - US
Evaluating utility and improving implementation of genomic sequencing for pediatric cancer patients in the diverse population and healthcare settings of Texas: the kidscanseq study
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US
Personalized whole body staging for children with cancer: a solution to the conundrum of long-term side effects from ct and pet/ct scans
Institution: Information not provided - US

Washington
ADDRESS: NOT PROVIDED - US
Project 1: optimization of therapeutic approaches for children with relapsed sarcomas using precision medicine.
Institution: Information not provided - US

Madrid
MADRID
Mechanistic models using Machine Learning for therapeutic targets discovery and drug repurposing in Rare Diseases
ISCIII - Instituto de Salud Carlos III
Centro de Investigación Biomédica en Red de Enfermedades Raras
Multicentric Research projects
- Universitätsklinikum Mannheim
- European Leukemia Net - Network Management Center
- Institution: Information not provided - IT
- Institution: Information not provided - IT
- Institution: Information not provided - IT
- St. Anna Kinderkrebsforschung
- Children's Cancer Research Institute
- Institution: Information not provided - DE
- Institution: Information not provided - IT
- Fondazione IRCCS Istituto Nazionale dei Tumori
- S.S. di Epidemiologia Valutativa
- Fondazione IRCCS Istituto Nazionale dei Tumori
- S.S. di Epidemiologia Valutativa
- Northern Institute for Cancer Research, Medical School, Newcastle University
- Northern Institute for Cancer Research
- Institut Curie
- Macromolécules et Microsystèmes en Biologie et en Medecine

Baden-Württemberg
MANNHEIM
EUROPEAN LEUKEMIA NET: Strengthen and develop scientific and technological excellence in research and therapy of leukemia

EMILIA ROMAGNA
ADDRESS: NOT PROVIDED - IT
DRAMA: Defeating Recurrence and resistance in AML: Multigenomic Approaches to analyse heterogeneity

EMILIA ROMAGNA
ADDRESS: NOT PROVIDED - IT
HLALOSS: New technologies for early detection of HLA loss leukemia relapse after allogeneic hematopoietic stem cell transplantation, and identification of relevant risk factors.

EMILIA ROMAGNA
ADDRESS: NOT PROVIDED - IT
HAPLO-IMMUNE: Validation of immune biomarkers predictive of clinical outcome after HLA-haploidentical hematopoietic stem cell transplantation for acute leukemia

WIEN
WIEN
ENCCA: European Network for Cancer Research in Children and Adolescents

Berlin
ADDRESS: NOT PROVIDED - DE
TORPEDO: Targeting Of Resistance in PEDiatric Oncology

EMILIA ROMAGNA
ADDRESS: NOT PROVIDED - IT
TRANSCAN-2: Aligning national/regional translational cancer research programmes and activities

LOMBARDIA
MILANO
RARECARE: surveillance of rare cancers in Europe

LOMBARDIA
MILANO
RARECARENet: Network informativo sui tumori rari

Tyne & Wear
NEWCASTLE UPON TYNE
EPOC: European paediatric oncology off-patent medicines consortium

ILE-DE-FRANCE
ORSAY