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Funded by an IRDiRC member = Member of a ERN =

Research projects

AUSTRIA

WIEN
ADDRESS: NOT PROVIDED - AT

AUSTRIA

WIEN
ADDRESS: NOT PROVIDED - AT

AUSTRIA

WIEN
WIEN

CDK 4/6 inhibitors as a new therapeutic strategy in pediatric brain tumors
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Neonatologie, Pädiatrische Intensivmedizin und Neuropädiatrie

AUSTRIA

WIEN
WIEN

Funded by an IRDiRC memberBRCAddict: Harnessing BRCAness as a therapeutic target in high-risk pediatric solid tumors - AT
Allgemeines Krankenhaus der Stadt Wien
Universitätsklinik für Kinder- und Jugendheilkunde

AUSTRIA

WIEN
WIEN

Pharmacokinetics of different antibiotics in cerebrospinal fluid in children with malignant brain tumors - a pilot study
Allgemeines Krankenhaus der Stadt Wien
Universitätsklinik für klinische Pharmakologie

FINLAND

Finland
KUOPIO

New therapeutic treatments for malignant glioma
Itä-Suomen yliopisto
A.I.Virtanen -Instituutti

FINLAND

Finland
KUOPIO

Funded by an IRDiRC memberLAT1-targeted prodrugs for improved drug delivery to invasive glioma cells
University of Eastern Finland
Faculty of Health Sciences

FRANCE

AUVERGNE-RHONE-ALPES
ILLKIRCH

Systems biology of integrin inhibition-induced apoptosis for novel glioblastoma treatment
LBP - Laboratory of Bioimaging and Pathologies
Tumoral signaling and therapeutic targets

FRANCE

PROVENCE-ALPES-COTE D'AZUR
MARSEILLE

Development of a new drug therapy for glioblastoma
Parc scientifique et technologiques de Luminy
Pharmaxon

GERMANY

Nordrhein-Westfalen
DÜSSELDORF

Targeting HOTAIRM1 in Glioblastoma Multiforme
Universitätsklinikum Düsseldorf
Hirntumor-Referenzzentrum der DGNN

PORTUGAL

CENTRO
BRAGA

SPAIN

Andalucía
SEVILLA

Funded by an IRDiRC memberClinical and preclinical study of the "immune-barrier" effect in the glioblastoma environment: A novel tool to improve cancer patients´ stratification for immunotherapy
Hospital Universitario Virgen del Rocío
FISEVI - Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

SPAIN

Baleares
PALMA DE MALLORCA

Funded by an IRDiRC memberIntegrative characterization of molecular biomarkers for the precision diagnosis and treatment of patients with glioblastoma
IdISBa - Fundació Institut d'Investigació Sanitaria Illes Balears
BIOCANCER: Grupo de Biología Celular del Cáncer

SPAIN

Castilla - La Mancha
ALBACETE

Funded by an IRDiRC memberNanomedicine for glioblastoma therapy
Universidad de Castilla-La Mancha. Campus de Albacete. Facultad de Medicina
Unidad Neurodeath

SPAIN

Cataluña
BADALONA

SPAIN

Cataluña
L'HOSPITALET DE LLOBREGAT

Funded by an IRDiRC memberMR Spectroscopy prognostic assessment of brain gliomas (MRS-PROG)
IDIBELL - Instituto de Investigación Biomédica de Bellvitge
Instituto de Investigación Biomédica de Bellvitge

SPAIN

Comunidad Valenciana
VALENCIA

Funded by an IRDiRC memberIntegrative personal omics profiles in glioblastoma recurrence and therapy resistance
IIS La Fe - Instituto de Investigación Sanitaria La Fe
GIBI230: Grupo de Investigación Biomédica en Imagen

SPAIN

Galicia
SANTIAGO DE COMPOSTELA

Funded by an IRDiRC memberSilk-fibroin interventional nano-trap for the treatment of glioblastoma
Universidad de Santiago de Compostela. Facultad de Farmacia
I+D Farma

SPAIN

Madrid
MADRID

Funded by an IRDiRC memberNanomedicine for glioblastoma therapy
Hospital Universitario Ramón y Cajal
Servicio de Oncología Médica

SPAIN

Madrid
MADRID

Funded by an IRDiRC memberValidation of the MGMT epigenetic biomarker in liquid biopsy as a non-invasive test in patients with gliomas
IdiPAZ - Instituto de Investigación Sanitaria del Hospital Universitario La Paz
Fundación para la Investigación Biomédica del H.U. La Paz

SPAIN

Navarra
PAMPLONA

Funded by an IRDiRC memberRole of RNU6 isolated from circulating exosomes as a potential diagnostic and follow-up biomarker for patients with glioblastoma
CIMA - Centro de Investigación Médica Aplicada
Grupo de Terapias avanzadas para tumores sólidos pediátricos

SPAIN

Navarra
PAMPLONA

Funded by an IRDiRC memberPlasma extracellular vesicles (EVs): the key for precision medicine in Glioblastoma
IdiSNA - Instituto de Investigación Sanitaria de Navarra
Instituto de Investigación Sanitaria de Navarra

SPAIN

País Vasco
DERIO

Funded by an IRDiRC memberPlasma extracellular vesicles (EVs): the key for precision medicine in Glioblastoma
Centro de Investigación Cooperativa en Biociencias (CIC bioGUNE)
Centro de Investigación Cooperativa en Biociencias

SWITZERLAND

Suisse Alémanique
BASEL

SWITZERLAND

Suisse Alémanique
BERN

SWITZERLAND

Suisse Romande
LAUSANNE

Epigenetic landscape of gliomas and their implications for tumor biology and treatment of cancer II
Centre Hospitalier Universitaire Vaudois CHUV
Laboratoire de biologie et génétique des tumeurs cérébrales (LBGT)

UNITED KINGDOM

Cambridgeshire
CAMBRIDGE

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberImmunobiology of malignant glioma
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberGlioblastoma stem cell-derived pericytes and cancer invasion
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberModeling malignant progression in glioma
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberNeuronal activity-regulated mechanisms of glioma growth
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberNeuroimmunology of malignant brain tumors: innate mechanisms
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberRole of glud2 as a metabolic driver of gliomas with idh1 mutations
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberSystemic gene therapy for glioblastoma
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberThe mayo gbm xenograft national resource
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberTargeting epha2 in glioblastoma
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberSelective targeting of glioma stem cells through sema3c/plexind1
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberUbiquitination and deubiquitination of c-myc in glioblastoma
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberChromatin modifications in gbm-propagating cells
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberCellular plasticity and equilibrium in gbm progression
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberExploiting mtap deletion for gbm therapeutics
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberMechanisms of riok2 function in glioblastoma
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberThe role of tumor associated macrophages in glioblastoma
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberTargeting kif11 to treat glioblastoma invasion and proliferation
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberPhysical-chemical aspects of cell and tissue excitability
Institution: Information not provided - US

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberTherapeutically relevant targets of twist1 dimers in glioma
Institution: Information not provided - US

AUSTRIA

WIEN
WIEN

Funded by an IRDiRC memberITCC-P4: Pediatric Preclinical Proof of Concept Platform - AT
Medizinische Universität Wien
Institut für Krebsforschung

GERMANY

Baden-Württemberg
HEIDELBERG

INFORM-Registry: INdividualized Therapy FOr Relapsed Malignancies in Childhood
Deutsches Krebsforschungszentrum
Klinische Kooperationseinheit Pädiatrische Onkologie

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

Funded by an IRDiRC memberTargeting olig2 co-regulators for malignant glioma therapy
Institution: Information not provided - US

CANADA

Québec
MONTRÉAL

Funded by an IRDiRC memberIdentification and characterization of genes involved in the genesis and progression of pediatric astrocytomas
Montreal Children's Hospital Research Institute - McGill University
Department of Pediatrics / Département de pédiatrie

CANADA

Québec
MONTRÉAL

Funded by an IRDiRC memberRole of chromatin remodeling in the genesis of pediatric and young adult astrocytomes
Montreal Children's Hospital Research Institute - McGill University
Department of Pediatrics / Département de pédiatrie

CANADA

Québec
MONTRÉAL

Funded by an IRDiRC memberThe ICHANGE (International CHildhood Astrocytomas iNtegrated Genomics and Epigenomics) Consortium
Montreal Children's Hospital Research Institute - McGill University
Department of Pediatrics / Département de pédiatrie

CANADA

Québec
MONTRÉAL

Funded by an IRDiRC memberTackling childhood brain cancer at the root to improve survival and quality of life
The Research Institute of the McGill University Health Centre

AUSTRIA

WIEN
ADDRESS: NOT PROVIDED - AT

GliMR2.0: Glioma MR Imaging 2.0 - AT
Institution: Information not provided - AT

AUSTRIA

WIEN
WIEN

Improved Visualization and Resection of Brain Tumors with Quantitative Fluorescence and Optical Coherence Tomography
Allgemeines Krankenhaus der Stadt Wien
Universitätsklinik für Neurochirurgie

GERMANY

Nordrhein-Westfalen
MÜNSTER

Functional role of genes and pathways in histone H3 mutated gliomas
Institut für Neuropathologie der Medizinischen Fakultät Münster
Institut für Neuropathologie

GERMANY

Rheinland-Pfalz
MAINZ

GLIOPT -Glioma patients in ambulatory care - Optimization of psychosocial care in neurooncological patients
Universitätsmedizin Mainz
Universitäres Centrum für Tumorerkrankungen (UCT) Mainz

IRELAND

County Dublin
DUBLIN

PORTUGAL

SUL
LISBOA

Role of protein kinase WNK2 as a tumour suppressor gene in malignant gliomas
Instituto Nacional de Saúde Dr. Ricardo Jorge - Lisboa
Unidade de Investigação e Desenvolvimento

SWEDEN

Region Uppsala
UPPSALA

Molecular mechanisms of the origine of glioma development
Uppsala Universitet
Department of Immunology, Genetics and Pathology

SWITZERLAND

Suisse Alémanique
BERN

Metabolic Characterization of Space Occupying Lesions of the Brain Using in Vivo MR- (Spectroscopic) Imaging at 3 Tesla and 7 Tesla
Universitätsspital Inselspital
Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie

SWITZERLAND

Suisse Alémanique
ZÜRICH

To reveal and target molecular interactions causative for pro-invasive signaling in malignant brain tumors
Universitäts-Kinderspital Zürich
Abteilung Onkologie - Experimental Infectious Diseases and Cancer Research

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

AUSTRIA

WIEN
WIEN

Deep Learning for Precision Diagnostics of Brain Tumors
Allgemeines Krankenhaus der Stadt Wien
Abteilung für Neuropathologie und Neurochemie

AUSTRIA

WIEN
WIEN

Christian Doppler Laboratory for Next Generation CAR-T Cells
St. Anna Kinderkrebsforschung
Children's Cancer Research Institute

BELGIUM

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

CANADA

Ontario
TORONTO

GERMANY

Baden-Württemberg
HEIDELBERG

Funded by an IRDiRC memberERA-NET TRANSCAN: BRCAddict - BRCAness as a therapeutic target for solid high-risk childhood tumors
Deutsches Krebsforschungszentrum
KITZ - Hopp-Kindertumorzentrum Heidelberg

ITALY

VENETO
PADOVA

Funded by an IRDiRC memberModulating BMP axis to prevent muscle loss, dismantling of NMJ and denervation in cancer cachexia
Venetian Institute of Molecular Medicine
Fondazione per la ricerca Biomedica avanzata ONLUS

UNITED STATES

Washington
ADDRESS: NOT PROVIDED - US

SPAIN

Madrid
MADRID

Funded by an IRDiRC memberMechanistic models using Machine Learning for therapeutic targets discovery and drug repurposing in Rare Diseases
ISCIII - Instituto de Salud Carlos III
Centro de Investigación Biomédica en Red de Enfermedades Raras

Multicentric Research projects