x

Rechercher un projet de recherche

* (*) Champ obligatoire

110 Résultat(s)

Trier par

Financé par un membre IRDiRC = Membre d'un ERN =

Projets de recherche

ETATS-UNIS

Arizona
PHOENIX

Financé par un membre IRDiRCThe etiology of inherited neurological diseases
Phoenix Children's Hospital
Barrow Neurological Institute

ESPAGNE

Comunidad Valenciana
VALENCIA

Financé par un membre IRDiRCClinical studies, genetic bases and prognostic biomarkers in rare neurodegenerative diseases
Centro de Investigación Príncipe Felipe (CIPF)
Unidad de Genética y Genómica de Enfermedades Neuromusculares y Neurodegenerativas

ESPAGNE

Madrid
MADRID

ETATS-UNIS

Washington
ADDRESS: NOT PROVIDED - US

IRLANDE

County Dublin
DUBLIN

PORTUGAL

NORTE
PORTO

SPATAX: Clinical and Genetic Analysis of Cerebellar Ataxias and Spastic Paraplegias
Instituto de Biologia Molecular e Celular
Centro de Genética Preditiva e Preventiva

PORTUGAL

NORTE
PORTO

Clinical implications of genetic factors causing neurodegenerative diseases characterized by movement or cognitive dysfunction.
Instituto de Biologia Molecular e Celular
Unidade de Investigação Genética e Epidemiológica em Doenças Neurológicas

PORTUGAL

NORTE
PORTO

Mapping and identification of new disease genes in autosomal dominant spinocerebellar ataxias
Instituto de Biologia Molecular e Celular
Unidade de Investigação Genética e Epidemiológica em Doenças Neurológicas

PORTUGAL

NORTE
PORTO

SPATAX: Clinical and Genetic Analysis of Cerebellar Ataxias and Spastic Paraplegias
Instituto de Biologia Molecular e Celular
Unidade de Investigação Genética e Epidemiológica em Doenças Neurológicas

PORTUGAL

NORTE
SANTA MARIA DA FEIRA

ALLEMAGNE

Baden-Württemberg
HEIDELBERG

Financé par un membre IRDiRCADDRess: Translational research for patients with abnormal DNA Damage Response
Deutsches Krebsforschungszentrum
KITZ - Hopp-Kindertumorzentrum Heidelberg

ALLEMAGNE

Baden-Württemberg
HEIDELBERG

Financé par un membre IRDiRCADDRess: Translational research for patients with abnormal DNA Damage Response
Universitäts-Frauenklinik Heidelberg
Frauenheilkunde und Geburtshilfe

ALLEMAGNE

Bayern
WÜRZBURG

Financé par un membre IRDiRCADDRess: Translational research for patients with abnormal DNA Damage Response
Universität Würzburg - Biozentrum
Institut für Humangenetik

ALLEMAGNE

Nordrhein-Westfalen
BONN

rTMS_SCA: Repetitive transcranial magnetic stimulation (rTMS) in patients with SCA and CANVAS.
Universitätsklinikum Bonn (AöR)
Klinik und Poliklinik für Neurologie

ALLEMAGNE

Nordrhein-Westfalen
DÜSSELDORF

Financé par un membre IRDiRCADDRess: Translational research for patients with abnormal DNA Damage Response
Universitätsklinikum Düsseldorf
Institut für Pathologie

CANADA

Ontario
TORONTO

ETATS-UNIS

Washington
ADDRESS: NOT PROVIDED - US

Financé par un membre IRDiRCA powerful web-based discovery platform for rare disease genetics
Institution: Information not provided - US

FRANCE

GRAND-EST
ILLKIRCH-GRAFFENSTADEN

Financé par un membre IRDiRCDrugFXTAS : Recherche d'une thérapie pour FXTAS
Institut de génétique et de biologie moléculaire et cellulaire - IGBMC
Département Médecine translationnelle et neurogénétique

FRANCE

ILE-DE-FRANCE
PARIS

Financé par un membre IRDiRCSTaHR : Stimulation de la Recombinaison Homologue pour la Thérapie Génique - FR
Muséum National d'Histoire Naturelle
Laboratoire Structure et Instabilité des Génomes - INSERM U1154 - CNRS 7196

FRANCE

PAYS DE LA LOIRE
NANTES

Financé par un membre IRDiRCFROGH : Etude Génétique de la Population Française - FR
Institut de Recherche en Santé - Université de Nantes
L'Institut du thorax - Inserm UMR 1087 / CNRS UMR 6291

ITALIE

LAZIO
ROMA

Financé par un membre IRDiRCDiverse rare diseases caused by functional dysregulation of Rho GTPase-related proteins
ISS - Istituto Superiore di Sanità
Centro Nazionale Malattie Rare

JAPON

JAPAN
KUMAMOTO

Financé par un membre IRDiRCDevelopment of therapeutic agents for Fragile X associated tremor/ataxia syndrome (FXTAS).
Institute of Molecular Embryology and Genetics, Kumamoto University
Department of Genomic Neurology

JAPON

JAPAN
TOKYO

Financé par un membre IRDiRCFormation of integrated omics analysis base of refractory diseases in children and perinatal period
National Center for Child Health and Development
Research Institute

PORTUGAL

NORTE
PORTO

CACNA1A gene involvement in cognition and synaptic function in calcium channel disease.
Instituto de Biologia Molecular e Celular
Unidade de Investigação Genética e Epidemiológica em Doenças Neurológicas

ALLEMAGNE

Baden-Württemberg
TÜBINGEN

Financé par un membre IRDiRCSCA-CYP: Gene Therapy for Cerebellar Ataxias: restoring cholesterol metabolism by targeting brain cholesterol 24 hydroxylase (CYP46A1) (partner No 3)
Institut für Medizinische Genetik und angewandte Genomik Tübingen
Institut für Medizinische Genetik und angewandte Genomik

ALLEMAGNE

Bayern
NEUHERBERG

ALLEMAGNE

Hessen
FRANKFURT AM MAIN

ALLEMAGNE

Hessen
FRANKFURT AM MAIN

CAG102-knock-in model for spinocerebellar ataxia type 2
Neurologische Universitätsklinik
Klinik für Neurologie

CANADA

Québec
JONQUIÈRE

Financé par un membre IRDiRCNew Emerging Team on Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS): from models to treatment strategies
CSSS - Centre de santé et de services sociaux de Jonquière
Centre de réadaptation Le Parcours

CANADA

Québec
MONTRÉAL

CANADA

Québec
MONTRÉAL

CANADA

Québec
MONTRÉAL

Financé par un membre IRDiRCNew Emerging Team on Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS): from models to treatment strategies
McGill University - McIntyre Medical Sciences Building
Department of Pharmacology & Therapeutics

CANADA

Québec
QUÉBEC

ESPAGNE

Comunidad Valenciana
VALENCIA

Genomic edition of the FXN Gene through the CRISPR / Cas9 system in lymphocytes of patients with Friedreich's ataxia
INCLIVA - Facultad de Medicina de la Universidad de Valencia
Grupo de investigación en fisiopatología celular y orgánica del estrés oxidativo

ESPAGNE

Comunidad Valenciana
VALENCIA

Validation of circulating microRNAs as prognostic biomarkers and clinical evolution in Friedreich ataxia. Towards precision medicine in Rare Diseases
INCLIVA - Facultad de Medicina de la Universidad de Valencia
Grupo de investigación en fisiopatología celular y orgánica del estrés oxidativo

ESPAGNE

Comunidad Valenciana
VALENCIA

Financé par un membre IRDiRCNew Therapies in Friedreich Ataxia
INCLIVA - Facultad de Medicina de la Universidad de Valencia
Grupo de investigación en fisiopatología celular y orgánica del estrés oxidativo

ETATS-UNIS

South Dakota
SOUTH DAKOTA

Financé par un membre IRDiRCAberrant mitochondrial redox regulation in Friedreich's Ataxia
Sanford Research/University of South Dakota
VITIELLO LAB- Depatment of Pediatrics

ETATS-UNIS

Washington
ADDRESS: NOT PROVIDED - US

Financé par un membre IRDiRCNatural history of spinocerebellar ataxia type 7 (sca7)
Institution: Information not provided - US

ETATS-UNIS

Washington
ADDRESS: NOT PROVIDED - US

ETATS-UNIS

Washington
ADDRESS: NOT PROVIDED - US

Financé par un membre IRDiRCMammalian iron-sulfur cluster biogenesis
Institution: Information not provided - US

FINLANDE

Finland
HELSINKI

The rare diseases of Finnish heritage MIRAS, IOSCA, AHS and EPM1 and their disease mechanisms
University of Helsinki
Stem Cells and Metabolism Research Program

FINLANDE

Finland
KUOPIO

The rare diseases of Finnish heritage MIRAS, IOSCA, AHS and EPM1 and their disease mechanisms
University of Eastern Finland
Institute of Clinical Medicine

FRANCE

AUVERGNE-RHONE-ALPES
PRAGUE

Financé par un membre IRDiRCPig models for Ataxia telangiectasia and Batten disease
Faculty of Medicine and University Hospital Motol
Department of Pediatrics

FRANCE

GRAND-EST
ILLKIRCH-GRAFFENSTADEN

Etude du potentiel prolifératif et régénératif des photorécepteurs dans le modèle murin SCA7, une maladie par expansion de polyglutamine
Institut de génétique et de biologie moléculaire et cellulaire - IGBMC
Département Médecine translationnelle et neurogénétique

FRANCE

ILE-DE-FRANCE
PARIS

BIOSCA: Identification de biomarqueurs de l' évolution de la maladie dans les ataxies cérébelleuses autosomiques dominantes
APHP.Sorbonne Université, Hôpital de la Pitié-Salpêtrière
UF de Neurogénétique Moléculaire et Cellulaire

FRANCE

ILE-DE-FRANCE
PARIS

Etude observationnelle pluridisciplinaire des patients atteints d'une ataxie de Friedreich
CHU Paris - Hôpital Robert Debré
Neurologie pédiatrique et maladies métaboliques

FRANCE

PROVENCE-ALPES-COTE D'AZUR
MARSEILLE

Biologie synthétique et l'ataxie de Friedreich
CNRS Campus Joseph Aiguier
Laboratoire de Chimie Bactérienne (LCB) - UMR 7283

FRANCE

PROVENCE-ALPES-COTE D'AZUR
MARSEILLE

Financé par un membre IRDiRCFRACOL : Biologie synthétique et l'ataxie de Friedreich - FR
CNRS Campus Joseph Aiguier
Laboratoire de Chimie Bactérienne (LCB) - UMR 7283

ITALIE

LAZIO
ROMA

Molecular determinants of neurodegenerative diseases
IRCCS Ospedale Pediatrico Bambino Gesù - SEDE SAN PAOLO
Unità di Malattie Neuromuscolari e Neurodegenerative - Laboratorio di Medicina Molecolare

ITALIE

LOMBARDIA
MILANO

Financé par un membre IRDiRCA drosophila model to study the neurodegenerative disease Dentatorubral-pallidoluysian atrophy
IRCCS Ospedale San Raffaele
Divisione di Genetica e Biologia Cellulare - Dipartimento di Genomica Funzionale

ITALIE

LOMBARDIA
MILANO

Financé par un membre IRDiRCExcitatory/Inhibitory unbalance in Ataxia telangiectasia and perspective therapeutical interventions
Università degli Studi di Milano-Biotecnologie Mediche e Medicina Traslazionale
Dipartimento di Biotecnologie Mediche e Medicina Traslazionale - Laboratorio Interdisciplinare di Tecnologie Avanzate (LITA)

JAPON

JAPAN
NIIGATA

Financé par un membre IRDiRCDevelopment of therapeutic strategy for DRPLA based on gene silencing and genome editing.
Brain Research Institute, Niigata University
Department of Neurology

JAPON

JAPAN
TOKYO

Financé par un membre IRDiRCDeveloping antisense ol igonucleotide therapy targeting bidirectional transcription underlying an inherited neurodegenerative disease.
Tokyo Medical and Dental University Medical Hospital
Center for Personalized Medicine for Healthy Aging

JAPON

JAPAN
TOKYO

Financé par un membre IRDiRCGene therapy against SCA1 based on the molecular pathomechanism
Tokyo Medical and Dental University Medical Research Institute
Department of Neuropathology

PORTUGAL

CENTRO
ADDRESS: NOT PROVIDED - PT

PORTUGAL

CENTRO
ADDRESS: NOT PROVIDED - PT

PORTUGAL

CENTRO
BRAGA

PORTUGAL

CENTRO
COIMBRA

The role of calpain-mediated proteolysis of ataxin-3 in Machado-Joseph disease: a molecular therapy approach with viral vectors.
Centro de Neurociências da Universidade de Coimbra
Departmento de vectores e terapia génica

PORTUGAL

CENTRO
COIMBRA

Regulation by phosphorylation of ataxin-3, the mutated protein in Machado Joseph Disease
Centro de Neurociências da Universidade de Coimbra
Glutamatergic Synapses: Formation and regulation of synapses

PORTUGAL

NORTE
PORTO

A peptide aptamer-based approach to neurodegenerative disorders.
Instituto de Biologia Molecular e Celular
Protein Crystallography Group

PORTUGAL

NORTE
PORTO

Search for disease modifiers in spinocerebellar ataxias: human and animal-based approaches.
Instituto de Biologia Molecular e Celular
Unidade de Investigação Genética e Epidemiológica em Doenças Neurológicas

SUEDE

Region Stockholm
STOCKHOLM

The role of an atrophin-brakeless protein complex in gene regulation and neurodegeneration in particularly
Stockholm University
Department of Molecular Biosciences, The Wenner-Gren Institute (MBW)

SUISSE

Suisse Alémanique
BERN

Swiss Primary Hypersomnolence and Narcolepsy Cohort Study
University Hospital Inselspital
Universitätsklinik für Neurologie

SUISSE

Suisse Alémanique
SCHLIEREN

Hematopoietic Stem Cell Gene Therapy for treatment of Ataxia telangiectasia (A-T)
Institute for Regenerative Medicine
Department Gene and Cell Therapy

SUISSE

Suisse Romande
LAUSANNE

ETATS-UNIS

Washington
ADDRESS: NOT PROVIDED - US

Financé par un membre IRDiRCMechanisms of retinal degeneration in inherited diseases
Institution: Information not provided - US

ETATS-UNIS

Washington
ADDRESS: NOT PROVIDED - US

Financé par un membre IRDiRCZfp423 mechanisms in joubert syndrome and related disorders
Institution: Information not provided - US

ETATS-UNIS

Washington
ADDRESS: NOT PROVIDED - US

ETATS-UNIS

Washington
ADDRESS: NOT PROVIDED - US

Financé par un membre IRDiRCGenetic architecture and molecular pathogenesis of joubert syndrome
Institution: Information not provided - US

ITALIE

LOMBARDIA
MILANO

Joubert syndrome and other genetic cerebellar malformations. In vivo analysis in animal models
IRCCS Ospedale San Raffaele
U.O. di Genetica dello Sviluppo Neurale

Projets de recherche multicentriques