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Progetti di ricerca

ILE-DE-FRANCE
PARIS
Familial aortic dissection: clinic and genetic study
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Research for one gene involved in Goldenhar syndrome
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Pathophysiology of mental retardation: Fragile X syndrome and mental retardation associated with the FRAXE site on Xq28
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Physiopathological studies of Lowe's syndrome and Dent's disease, two clinical entities with common molecular basis?
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Bardet-Biedl syndrome: new genes identification and biological characterization of a new gene BBS10
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
CMTHER: CMT1A phenotype correction by modulating molecules for PMP22 gene expression : role of ascorbic acid and other molecules
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
RIBODBA: Blackfan-Diamond anemia: molecular mechanisms of a ribosomal disease
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Schwartz-Jampel syndrome and perlecan deficiency: test of new chemical therapeutic approaches on patients cells and study of physiopathological mechanisms in murine model
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
GT-AAVRPGRIP: evaluation of a recombinant Adeno-Associated Vector serotype 5 (rAAV-5) vector for the gene replacement therapy of a new canine model of Leber congenital amaurosis (LCA) : the Dachshund dog RPGRIP-/-
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
New therapeutic strategies development for oculopahryngeal muscular dystrophy using a drosophila model
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Pathology of glial cells due to factor eIF2B mutations : molecular and physiopathological approaches, therapeutic development
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Bernard-Soulier Syndrome and MYH9 associated diseases: study of blood platelets anomalies and of the thrombopoïesis, correction by genetic therapy
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Model contribution in the microeconomic assessment of therapeutic strategies in Wegener granulomatosis
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Survey of the interest of ovarian cortex cryoconservation of girls affected by Turner syndrome: search for clinical and hormonal critera to select patients and caryotypic correlations
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Study of penetrance of C282Y homozygocity in hereditary hemochromatosis
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Search for genetic variants modifying human iron homeostasis
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
ONCOPLURISTEM: models of pluripotent stem cells from chronic myeloid leukemia (CML): generation of new therapeutic tools for screening
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
IFRA-2: Inflammation and alveolar repair in severe acute respiratory syndrome
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
CELLPATH: characterization of host cell pathways altered by effectors of Brucella, Chlamydia and Coxiella: identification of novel therapeutics targets
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
DCD-CANC-CHILD: design of drug carrier and delivery control for cancer therapy of children
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Physiopathological study of gastrointestinal smooth muscle and Chronic Intestinal Pseudo-Obstruction (CIPO)
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
First study in France searching a link between Amyotrophic Lateral Sclerosis (ALS) and beta-N-methylamino-L-alanine (BMAA) cyanotoxin
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Genetics and molecular bases of oesophageal atresia
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Genetics and molecular bases of central hypoventilation syndromes (Ondine's Curse)
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Genetics and molecular bases of malformative syndromes with tumour predisposition
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
SCD-Mec: Developmental mechanisms underlying human structural cerebellum defects
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
NanoPlanSYN : Role of the Planar Cell Polarity (PCP) signaling in the dynamic organization of synapses and the integration of synaptic information: from basic mechanisms to patho-physiological consequences
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
DynaMitoQ10: An unexpected link between mitochondrial dynamics and the mevalonate pathway: a new pathophysiological mechanism in mitochondrial disease
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
GSD1Nephro : Molecular characterization of the long-term onset of nephropathy and new treatments in glycogen storage diseases type 1
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
CaGeD : Cardiogenic Genome Dynamics
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
CoVeR: Contribution of the Vascular Smooth Muscle Cell-associated Type I cytokine receptors to Pulmonary Arterial Hypertension: At the interface between inflammation and pulmonary vascular remodeling
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
MTREAT-2: Targeting Matriptase-2 to develop new therapeutic strategies for iron related disorders
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Ubinergy: Control of mitochondrial energy metabolism by the ubiquitin/proteasome system
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
DrugFXTAS: Identify a therapy strategy for FXTAS
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
TRACeGSDIII : Translational optimization of AAV vectors to cure GSDIII
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
FROGH : FRench Regional Origins in Genetics for Health - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
DM_Neuroglia : RNA toxicity and neuroglial miscommunication in myotonic dystrophy brains - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Genetransnephrose: Genetic and translational studies in patients with steroid sensitive nephrotic syndrome - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
GENMSMD: Human genetic dissection of Mendelian susceptibility to mycobacterial disease - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
I-CARE: MItral Valve Disease: From Genetics to Mechanisms and Improved CARE - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
TAMIRAH: Targeting activated mineralocorticoid receptor in Pulmonary Arterial Hypertension: A translational approach towards treatment - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
STaHR : Stimulation of Targeted Homologous Recombination for Gene Therapy - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
AMEDYST: Alterations of motor networks in primary dystonia - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
DoseX : Regulation and function of gene dosage compensation on the X chromosome - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
EpiHD: Role of epigenetic mechanisms in Huntington's disease - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
FRACOL: Synthetic biology to approach Friedreich ataxia - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Rescue_ribosome : Rescue Pathways for unrecycled ribosomes - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
riboOPMD: Ribosomal and small non-coding RNAs in oculopharyngeal muscular dystrophy - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
spEJCificity: Characterization of pre-EJC factors and their role in cell fate determination - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
DIVERCIL: Understanding cilia and flagella diversity - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
B9inPAH: BMP9 as a major regulator of vascular tone in Pulmonary Arterial Hypertension: a promising new therapeutic target - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
MGonDev: Understanding the Mechanisms of Human Gonadal Development - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
OSTEOVALYMPH: Autocrine/paracrine CXCL12/CXCR4-CXCR7 signaling within the bone marrow osteo-vascular niche: impact on lymphoid specification and commitment of hematopoietic stem cells - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
PAPIS: Pediatric and Adult Plasticity of Intestinal SMCs - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Pheno2Geno: Regulation of NKCC2 and NCC by Protein-Protein interactions: From salt losing tubulopathies to salt sensitive hypertension - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
T-JUST: Tight junctions: from structure to treatment - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Vasorin: Role of Vasorin in the kidney, bone and arterial crosstalk - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
C9ORF72-ALS : Role of C9ORF72 in Amyotrophic Lateral Sclerosis - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
DEMENTIA : Exploiting genetic biomarkers of neurodegenerative diseases for developing early diagnostic tests and possible treatments - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
FMFgeneToDiag : Familial Mediterranean Fever (FMF) and FMF-like diseases: From genetics to functional diagnostic tests - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
MNaims : Molecular dissection of PLA2R1-related membranous nephropathy: towards a portfolio of new clinical biomarkers - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
NAD-HEART: NAD+ precursor supplementation for metabolic therapy of heart failure - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
TOLGEN: In vivo AAV-based gene transfer to the muscle: Deciphering host immune responses - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
BioCaps: Programmed drug release by rolled-up biopolymer capsules - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
eyePS: Modeling and treatment of retinal dystophies with iPS cells - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Parkington: Translational validation of neural organoid grafts for treating Parkinson's and Huntington diseases - FR
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Axonal Transport in SMALED, a Motor Neuron Disease.
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Modeling Rubinstein Taybi Syndrome Functionalization of a Rare Monogenic Disease and Therapeutic Potential of Stress Response Pathways in Neuropathies.
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Basophils in Lupus: Mechanisms and Therapy.
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Self-antigen-specific T lymphocyte signature during autoimmune liver diseases.
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Preclinical research on diseases caused by MI dysfunction
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Reduction of ganglioside synthesis as therapy for hereditary spastic paraplegia
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Targeting the vitamin D receptor for the treatment of rare diseases induced by calcitriosis
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
New gene therapy approaches for familial forms of amyotrophic lateral sclerosis
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Research of drugs and therapeutic targets for rare retinal dystrophies using cell models from patients
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Nano-droplet augmented brain therapy controlled by micro-machined capacitive transducers
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Study of the rupture of tissue homeostasis in polycystic kidney disease
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Mechanisms of regulation of muscle stem cell quiescence by the extracellular matrix of the niche
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Involvement of the ribosomal protein RPL13 in bone growth
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Innate immune deficiencies in severe brainstem infections
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Hereditary humoral immune deficiencies: genetics and pathological mechanisms
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Genomic editing by CRISPR / Cas9 to treat cardiomyopathies linked to mutations in the LMNA gene
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Fundamental, genetic and clinical aspects of male infertility caused by severe abnormalities of the sperm flagella
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Regulatory networks governing the diversity of craniofacial muscles
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Establish a model of follicular lymphoma in the chick embryo to personalize the treatment decision
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Spread and Toxicity of Pathogenic Factors in Amyotrophic Lateral Sclerosis
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Development of a new biotherapy targeting the inflammatory mechanisms of Netherton syndrome
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Innovative formulations based on deep eutectic solvents for the treatment of cutaneous leishmaniasis
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Retinal tissue engineering from human pluripotent stem cells for the treatment of retinal dystrophies
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
First preclinical validation of LOOK / ROCK inhibitors for the treatment of neurofibromatosis type 1
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
X-linked hypophosphatemia: from pathological mechanisms of mineralization to treatments for skeletal manifestations
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Activation of AHR and mechanisms of cell alteration in the myasthenia gravis model
ANR - Agence Nationale de la Recherche

ILE-DE-FRANCE
PARIS
Dynamin 2 expression modulation therapy
ANR - Agence Nationale de la Recherche
Progetti di ricerca multicentrici
- CHU de Grenoble et des Alpes - Institut de biologie et de pathologie
- Laboratoire de Génétique Moléculaire: maladies héréditaires et oncologie
- Institut de Biosciences et Biotechnologies de Grenoble (BIG) - CEA
- Laboratoire Biologie du Cancer et de l'Infection (BCI) - UMR 1036
- Faculté de Médecine Lyon Est
- Institut NeuroMyoGène (INMG) - CNRS UMR 5310 / INSERM U1217
- Université de Haute-Alsace (UHA) - Campus Illberg
- Institut de Science des Matériaux de Mulhouse (IS2M) - UMR7361 CNRS / UHA
- Inventiva
- Inventiva Pharma
- CHU Dijon Bourgogne - Hôpital François Mitterrand
- Service de Pneumologie - Soins Intensifs, Appareillage Respiratoire
- Faculté des Sciences de Santé
- Institut de Chimie Moléculaire de l'Université de Bourgogne (ICMUB) - CNRS 6302
- Institut de génétique et de biologie moléculaire et cellulaire - IGBMC
- Département Médecine translationnelle et neurogénétique
- Faculté de Psychologie de Strasbourg
- Laboratoire de Neurosciences Cognitives et Adaptatives (LNCA) - UMR 7364 / Université de Strasbourg / CNRS
- Faculté de Psychologie de Strasbourg
- Laboratoire de Neurosciences Cognitives et Adaptatives (LNCA) - UMR 7364 / Université de Strasbourg / CNRS
- Faculté de médecine de Strasbourg - Louis Pasteur
- Mécanismes centraux et périphériques de la Neurodégénérescence - INSERM U1118
- Faculté de Pharmacie - Université Paris-Sud
- Laboratoire "Signalisation et Physiopathologie Cardiovasculaire" - INSERM UMR-S 1180
- Institut Paris-Saclay d'Innovation thérapeutique (IPSIT)
- Unité "Inflammation, Chimiokines et Immunopathologie" - Inserm UMRS-996 / Université Paris-Sud
- GENOPOLE - Campus 1
- I-Stem - Institut des cellules Souches pour le Traitement et l'Etude des maladies Monogéniques
- GENOPOLE - Campus 1
- I-Stem - Institut des cellules Souches pour le Traitement et l'Etude des maladies Monogéniques
- Institut de Biologie Intégrative de la Cellule (I2BC)
- Département Biologie des Génomes
- CHU Paris-Sud - Hôpital de Bicêtre
- INSERM UMR 1169 - Thérapie Génique, Génétique et Epigénétique dans les Maladies Neurologiques, Diabète, Croissance
- Centre Chirurgical Marie Lannelongue
- Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique - Inserm UMR_S 999
- Université Paris Descartes - UFR Odontologie
- Laboratoire "Pathologie, Imagerie et Biothérapies orofaciales" - EA2496
- ANR - Agence Nationale de la Recherche
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- ANR - Agence Nationale de la Recherche
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- ANR - Agence Nationale de la Recherche
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- ANR - Agence Nationale de la Recherche
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- ANR - Agence Nationale de la Recherche
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- ANR - Agence Nationale de la Recherche
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- ANR - Agence Nationale de la Recherche
- ANR - Agence Nationale de la Recherche
- ANR - Agence Nationale de la Recherche
- ANR - Agence Nationale de la Recherche
- ANR - Agence Nationale de la Recherche
- ANR - Agence Nationale de la Recherche
- ANR - Agence Nationale de la Recherche
- ANR - Agence Nationale de la Recherche
- CHU Paris - Hôpital Robert Debré
- Equipe "Physiopathologie et neuroprotection des atteintes du cerveau en développement"
- CHU Paris - Hôpital Robert Debré
- Equipe "Physiopathologie et neuroprotection des atteintes du cerveau en développement"
- CHU Paris Est - Hôpital d'Enfants Armand-Trousseau
- Physiopathologie Des Maladies Génétiques d'Expression Pédiatrique - Inserm UMRS_933
- Centre de Recherches des Cordeliers (CRC)
- Equipe "Complément et Maladies"
- Centre de Recherches des Cordeliers (CRC)
- Equipe "Métabolisme et Physiologie Rénale"
- Centre de Recherches des Cordeliers (CRC)
- Equipe "Métabolisme et Physiologie Rénale"
- ENS - École Normale Supérieure
- Institut de Biologie de l'École Normale Supérieure (IBENS) - CNRS UMR8197 / Inserm U1024
- Groupe hospitalier AP-HP.6 - Hôpital Tenon
- INSERM UMRS 1155 "Des maladies rénales aux maladies fréquentes, remodelage et réparation"
- IFM - Institut du Fer à Moulin
- Equipe "Neurotransmission et signalisation"
- IMAGINE - Institut des Maladies Génétiques
- Equipe "Base moléculaire des maladies rénales héréditaires: néphronophtise et hypodysplasie"
- IMAGINE - Institut des Maladies Génétiques
- Equipe "Embryologie et Génétiques des malformations congénitales"
- IMAGINE - Institut des Maladies Génétiques
- Equipe "Génétique humaine des maladies infectieuses - Génétique Mendélienne"
- IMAGINE - Institut des Maladies Génétiques
- Equipe "Morphogenèse cardiaque"
- IMAGINE - Institut des Maladies Génétiques
- Equipe "Triplets CTG instables et dystrophie myotonique"
- IMAGINE - Institut des Maladies Génétiques
- Laboratoire des mécanismes moléculaires des troubles hématologiques et implications thérapeutiques
- Institut Pasteur
- Génomique et Epigénomique du Développement des Animaux - CNRS UMR3738
- Institut Pasteur
- Génétique du Développement Humain - CNRS UMR3738
- Institut de Myologie - Hôpital Pitié-Salpêtrière
- Équipe "Dystrophie Myotonique, Physiopathologie & Biothérapie"
- Institut de la Vision
- Centre de Recherche Institut de la Vision
- Muséum National d'Histoire Naturelle
- Laboratoire Structure et Instabilité des Génomes - INSERM U1154 - CNRS 7196
- Université Bordeaux 2 - Victor Ségalen
- Institut des Maladies Neurodégénératives (IMN) - CNRS UMR 5293
- CHU de Montpellier - Hôpital Arnaud de Villeneuve
- Laboratoire "Physiologie et Médecine Expérimentale du Coeur et des Muscles" - INSERM U1046 / CNRS UMR9214
- Institut de Génétique Humaine (IGH)
- Département Génétique et Développement
- IRS2 - Nantes Biotech
- Thérapie Génique Translationnelle des Maladies Génétiques
- Institut de Recherche en Santé - Université de Nantes
- L'Institut du thorax - Inserm UMR 1087 / CNRS UMR 6291
- Institut de Recherche en Santé - Université de Nantes
- L'Institut du thorax - Inserm UMR 1087 / CNRS UMR 6291
- CNRS Campus Joseph Aiguier
- Laboratoire de Chimie Bactérienne (LCB) - UMR 7283
- IPMC - Institut de Pharmacologie Moléculaire et Cellulaire
- Equipe "Physiopathologie moléculaire des phospholipases A2 & de leurs médiateurs"
- Deutsche Forschungsgemeinschaft
- UMC Utrecht - Universitair Medisch Centrum Utrecht
- Polikliniek Neuromusculaire Ziekten
- UMC Utrecht - Universitair Medisch Centrum Utrecht
- Polikliniek Neuromusculaire Ziekten

AUVERGNE-RHONE-ALPES
GRENOBLE
French network for genetic, cellular and clinical researches on Lowe syndrome

AUVERGNE-RHONE-ALPES
GRENOBLE
B9inPAH: BMP9 as a major regulator of vascular tone in Pulmonary Arterial Hypertension: a promising new therapeutic target

AUVERGNE-RHONE-ALPES
LYON
DIVERCIL: Understanding cilia and flagella diversity

AUVERGNE-RHONE-ALPES
MULHOUSE
BioCaps: Programmed drug release by rolled-up biopolymer capsules

BOURGOGNE-FRANCHE-COMTE
DAIX
HIPPOCURE : Development of inhibitors of YAP-TEAD interaction for the treatment of non-small cell lung cancer (NSCLC) and pleural malignant mesothelioma

BOURGOGNE-FRANCHE-COMTE
DIJON
SHOT-IPF: Small HSPs Inhibitors to Treat Idiopathic Pulmonary Fibrosis

BOURGOGNE-FRANCHE-COMTE
DIJON
DEMENTIA : Exploiting genetic biomarkers of neurodegenerative diseases for developing early diagnostic tests and possible treatments

GRAND-EST
ILLKIRCH-GRAFFENSTADEN
C9ORF72-ALS : Role of C9ORF72 in Amyotrophic Lateral Sclerosis

GRAND-EST
STRASBOURG
EpiHD: Role of epigenetic mechanisms in Huntington's disease

GRAND-EST
STRASBOURG
EpiFUS - Role of FUS in regulating epigenetic modifications: consequences for amyotrophic lateral sclerosis and frontotemporal dementia

GRAND-EST
STRASBOURG
ToFU: Interactions between TAU, FUS and TDP-43 in neurodegenerative diseases

ILE-DE-FRANCE
CHÂTENAY-MALABRY
NAD-HEART: NAD+ precursor supplementation for metabolic therapy of heart failure

ILE-DE-FRANCE
CLAMART
OSTEOVALYMPH: Autocrine/paracrine CXCL12/CXCR4-CXCR7 signaling within the bone marrow osteo-vascular niche: impact on lymphoid specification and commitment of hematopoietic stem cells

ILE-DE-FRANCE
EVRY
SightREPAIR: Preclinical validation of a stem cell-derived retinal pigmented epithelium for treatment of retinal degenerative diseases

ILE-DE-FRANCE
EVRY
SEDUCE : Stem cells for drug screening targeting splices

ILE-DE-FRANCE
GIF-SUR-YVETTE
Rescue_ribosome : Rescue Pathways for unrecycled ribosomes

ILE-DE-FRANCE
LE KREMLIN-BICÊTRE
Hdcyp: Restoring brain cholesterol metabolism : Development of clinical Gene therapy for Huntington's disease

ILE-DE-FRANCE
LE PLESSIS-ROBINSON
TAMIRAH : Targeting activated mineralocorticoid receptor in Pulmonary Arterial Hypertension: A translational approach towards treatment

ILE-DE-FRANCE
MONTROUGE
Vasorin: Role of Vasorin in the kidney, bone and arterial crosstalk

ILE-DE-FRANCE
PARIS
French network for genetic, cellular and clinical researches on Lowe syndrome

ILE-DE-FRANCE
PARIS
FROGH : FRench Regional Origins in Genetics for Health

ILE-DE-FRANCE
PARIS
AnBiCyst : Functional characterization of ANKS6/ANKS3/BICC1 complex and implication in cystic kidney diseases

ILE-DE-FRANCE
PARIS
SHOT-IPF: Small HSPs Inhibitors to Treat Idiopathic Pulmonary Fibrosis

ILE-DE-FRANCE
PARIS
TIEBET: TGF-Beta Signaling And Ineffective Erythropoiesis Of Beta-Thalassemia

ILE-DE-FRANCE
PARIS
DM_Neuroglia : RNA toxicity and neuroglial miscommunication in myotonic dystrophy brains

ILE-DE-FRANCE
PARIS
DYNEINOPATHY : Elucidating molecular and cellular mechanisms underlying dyneinopathies

ILE-DE-FRANCE
PARIS
MicroGol : Implication of the golgi apparatus secretory functions in the developpement Of postnatal microcephaly and intellectual disabilities

ILE-DE-FRANCE
PARIS
MitoMotor: CHCHD10 mutations: how mitochondrial dysfunction leads to motor neuron disease

ILE-DE-FRANCE
PARIS
ToFU: Interactions between TAU, FUS and TDP-43 in neurodegenerative diseases

ILE-DE-FRANCE
PARIS
Genetransnephrose: Genetic and translational studies in patients with steroid sensitive nephrotic syndrome

ILE-DE-FRANCE
PARIS
GENMSMD: Human genetic dissection of Mendelian susceptibility to mycobacterial disease

ILE-DE-FRANCE
PARIS
Heart_asymmetry: Early asymmetry required for the alignment of cardiac chambers : development and pathology

ILE-DE-FRANCE
PARIS
I-CARE: MItral Valve Disease: From Genetics to Mechanisms and Improved CARE

ILE-DE-FRANCE
PARIS
SightREPAIR: Preclinical validation of a stem cell-derived retinal pigmented epithelium for treatment of retinal degenerative diseases

ILE-DE-FRANCE
PARIS
TAMIRAH : Targeting activated mineralocorticoid receptor in Pulmonary Arterial Hypertension: A translational approach towards treatment

ILE-DE-FRANCE
PARIS
SEDUCE : Stem cells for drug screening targeting splices

ILE-DE-FRANCE
PARIS
COMPC3: Molecular mechanisms of the pathological stabilization of the complement system C3 convertase and its therapeutic control

ILE-DE-FRANCE
PARIS
STaHR : Stimulation of Targeted Homologous Recombination for Gene Therapy

ILE-DE-FRANCE
PARIS
THERADM : Modified MBNL gene therapy targeting nuclear expanded-CUG repeats to counteract toxic RNA gain-of-function in Myotonic Dystrophy

ILE-DE-FRANCE
PARIS
HIPPOCURE : Development of inhibitors of YAP-TEAD interaction for the treatment of non-small cell lung cancer (NSCLC) and pleural malignant mesothelioma

ILE-DE-FRANCE
PARIS
AMEDYST: Alterations of motor networks in primary dystonia

ILE-DE-FRANCE
PARIS
DoseX : Regulation and function of gene dosage compensation on the X chromosome

ILE-DE-FRANCE
PARIS
EpiHD: Role of epigenetic mechanisms in Huntington's disease

ILE-DE-FRANCE
PARIS
FRACOL: Synthetic biology to approach Friedreich ataxia

ILE-DE-FRANCE
PARIS
Rescue_ribosome : Rescue Pathways for unrecycled ribosomes

ILE-DE-FRANCE
PARIS
riboOPMD: Ribosomal and small non-coding RNAs in oculopharyngeal muscular dystrophy

ILE-DE-FRANCE
PARIS
spEJCificity: Characterization of pre-EJC factors and their role in cell fate determination

ILE-DE-FRANCE
PARIS
DIVERCIL: Understanding cilia and flagella diversity

ILE-DE-FRANCE
PARIS
B9inPAH: BMP9 as a major regulator of vascular tone in Pulmonary Arterial Hypertension: a promising new therapeutic target

ILE-DE-FRANCE
PARIS
MGonDev: Understanding the Mechanisms of Human Gonadal Development

ILE-DE-FRANCE
PARIS
OSTEOVALYMPH: Autocrine/paracrine CXCL12/CXCR4-CXCR7 signaling within the bone marrow osteo-vascular niche: impact on lymphoid specification and commitment of hematopoietic stem cells

ILE-DE-FRANCE
PARIS
PAPIS: Pediatric and Adult Plasticity of Intestinal SMCs

ILE-DE-FRANCE
PARIS
Pheno2Geno: Regulation of NKCC2 and NCC by Protein-Protein interactions: From salt losing tubulopathies to salt sensitive hypertension

ILE-DE-FRANCE
PARIS
T-JUST: Tight junctions: from structure to treatment

ILE-DE-FRANCE
PARIS
Vasorin: Role of Vasorin in the kidney, bone and arterial crosstalk

ILE-DE-FRANCE
PARIS
C9ORF72-ALS : Role of C9ORF72 in Amyotrophic Lateral Sclerosis

ILE-DE-FRANCE
PARIS
DEMENTIA : Exploiting genetic biomarkers of neurodegenerative diseases for developing early diagnostic tests and possible treatments

ILE-DE-FRANCE
PARIS
FMFgeneToDiag : Familial Mediterranean Fever (FMF) and FMF-like diseases: From genetics to functional diagnostic tests

ILE-DE-FRANCE
PARIS
Hdcyp: Restoring brain cholesterol metabolism : Development of clinical Gene therapy for Huntington's disease

ILE-DE-FRANCE
PARIS
MNaims : Molecular dissection of PLA2R1-related membranous nephropathy: towards a portfolio of new clinical biomarkers

ILE-DE-FRANCE
PARIS
NAD-HEART: NAD+ precursor supplementation for metabolic therapy of heart failure

ILE-DE-FRANCE
PARIS
TOLGEN: In vivo AAV-based gene transfer to the muscle: Deciphering host immune responses

ILE-DE-FRANCE
PARIS
BioCaps: Programmed drug release by rolled-up biopolymer capsules

ILE-DE-FRANCE
PARIS
eyePS: Modeling and treatment of retinal dystophies with iPS cells

ILE-DE-FRANCE
PARIS
Parkington: Translational validation of neural organoid grafts for treating Parkinson's and Huntington diseases

ILE-DE-FRANCE
PARIS
Project NETCALS: Network of Cohort Assessment in ALS

ILE-DE-FRANCE
PARIS
Project SOPHIA: Sampling and biomarker OPtimization and Harmonization In ALS and other motor neuron diseases

ILE-DE-FRANCE
PARIS
EpiFUS - Role of FUS in regulating epigenetic modifications: consequences for amyotrophic lateral sclerosis and frontotemporal dementia

ILE-DE-FRANCE
PARIS
MicroGol : Implication of the golgi apparatus secretory functions in the developpement Of postnatal microcephaly and intellectual disabilities

ILE-DE-FRANCE
PARIS
MitoMotor: CHCHD10 mutations: how mitochondrial dysfunction leads to motor neuron disease

ILE-DE-FRANCE
PARIS
FMFgeneToDiag : Familial Mediterranean Fever (FMF) and FMF-like diseases: From genetics to functional diagnostic tests

ILE-DE-FRANCE
PARIS
COMPC3: Molecular mechanisms of the pathological stabilization of the complement system C3 convertase and its therapeutic control

ILE-DE-FRANCE
PARIS
Pheno2Geno: Regulation of NKCC2 and NCC by Protein-Protein interactions: From salt losing tubulopathies to salt sensitive hypertension

ILE-DE-FRANCE
PARIS
T-JUST: Tight junctions: from structure to treatment

ILE-DE-FRANCE
PARIS
spEJCificity: Characterization of pre-EJC factors and their role in cell fate determination

ILE-DE-FRANCE
PARIS
Genetransnephrose: Genetic and translational studies in patients with steroid sensitive nephrotic syndrome

ILE-DE-FRANCE
PARIS
AMEDYST: Alterations of motor networks in primary dystonia

ILE-DE-FRANCE
PARIS
AnBiCyst : Functional characterization of ANKS6/ANKS3/BICC1 complex and implication in cystic kidney diseases

ILE-DE-FRANCE
PARIS
DYNEINOPATHY : Elucidating molecular and cellular mechanisms underlying dyneinopathies

ILE-DE-FRANCE
PARIS
GENMSMD: Human genetic dissection of Mendelian susceptibility to mycobacterial disease

ILE-DE-FRANCE
PARIS
Heart_asymmetry: Early asymmetry required for the alignment of cardiac chambers : development and pathology

ILE-DE-FRANCE
PARIS
DM_Neuroglia : RNA toxicity and neuroglial miscommunication in myotonic dystrophy brains

ILE-DE-FRANCE
PARIS
TIEBET: TGF-Beta Signaling And Ineffective Erythropoiesis Of Beta-Thalassemia

ILE-DE-FRANCE
PARIS
DoseX : Regulation and function of gene dosage compensation on the X chromosome

ILE-DE-FRANCE
PARIS
MGonDev: Understanding the Mechanisms of Human Gonadal Development

ILE-DE-FRANCE
PARIS
THERADM : Modified MBNL gene therapy targeting nuclear expanded-CUG repeats to counteract toxic RNA gain-of-function in Myotonic Dystrophy

ILE-DE-FRANCE
PARIS
eyePS: Modeling and treatment of retinal dystophies with iPS cells

ILE-DE-FRANCE
PARIS
STaHR : Stimulation of Targeted Homologous Recombination for Gene Therapy

NOUVELLE AQUITAINE
BORDEAUX
Parkington: Translational validation of neural organoid grafts for treating Parkinson's and Huntington diseases

OCCITANIE
MONTPELLIER
PAPIS: Pediatric and Adult Plasticity of Intestinal SMCs

OCCITANIE
MONTPELLIER
riboOPMD: Ribosomal and small non-coding RNAs in oculopharyngeal muscular dystrophy

PAYS DE LA LOIRE
NANTES
TOLGEN: In vivo AAV-based gene transfer to the muscle: Deciphering host immune responses

PAYS DE LA LOIRE
NANTES
FROGH : FRench Regional Origins in Genetics for Health

PAYS DE LA LOIRE
NANTES
I-CARE: MItral Valve Disease: From Genetics to Mechanisms and Improved CARE

PROVENCE-ALPES-COTE D'AZUR
MARSEILLE
FRACOL: Synthetic biology to approach Friedreich ataxia

PROVENCE-ALPES-COTE D'AZUR
VALBONNE
MNaims : Molecular dissection of PLA2R1-related membranous nephropathy: towards a portfolio of new clinical biomarkers

Nordrhein-Westfalen
BONN
EpiFUS - Role of FUS in regulating epigenetic modifications: consequences for amyotrophic lateral sclerosis and frontotemporal dementia

Utrecht
UTRECHT
Project NETCALS: Network of Cohort Assessment in ALS

Utrecht
UTRECHT