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AUSTRIA

WIEN
WIEN

Lung microbiome for screening imminent exacerbation in CF (cystic fibrosis)
Medizinische Universität Wien
Forschungslabor Infektionsbiologie

BELGIO

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

BELGIO

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

FLONAMUC: Epidemiology of the Nasal Flora at the Reference Center for Cystic Fibrosis of Queen Fabiola Children's University Hospital
Hôpital Universitaire des Enfants Reine Fabiola - HUDERF
Service de Pneumologie-Allergologie

BELGIO

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

MucoSWEATomics New Markers of CFTR Function in Sweat: Value for Diagnosis and Efficacy of Target Therapies
Université Catholique de Louvain (UCL)
Louvain centre for Toxicology and Applied Pharmacology

BELGIO

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUXELLES

Efflux as a mechanism of intrinsic and acquired resistance to antibiotics in Achromobacter xylosoxidans
Cellular and Molecular Pharmacology Unit, Louvain Drug Research Institute, UCL
Cellular and Molecular Pharmacology Unit

BELGIO

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUXELLES

Development of CFTR-stabilizers as therapeutic for cystic fibrosis
Structure et Fonction des Membranes Biologiques
Laboratoire Structure et Fonction des Membranes Biologiques

BELGIO

OOST-VLAANDEREN
GENT

Developing a personalized approach for antimicrobial susceptibility testing in cystic fibrosis
LPM Pharmaceutical Microbiology, Universiteit Gent
LPM Laboratory of Pharmaceutical Microbiology

BELGIO

VLAAMS BRABANT
LEUVEN

Development of drug based therapies to target rare mutations causing severe cystic fibrosis
Center for molecular medicine, Division of Molecular Virology and Gene Therapy
Molecular Virology and Gene Therapy

BELGIO

VLAAMS BRABANT
LEUVEN

Evaluation of CFTR function in cultured organoids from rectal biopsies in patients with Cystic Fibrosis
UZ Leuven - Campus Gasthuisberg
Dienst Kindergeneeskunde/Department of Pediatrics

BELGIO

VLAAMS BRABANT
LEUVEN

CANADA

Colombie-Britannique
VANCOUVER

Mechanisms of Hyperinfammation in Cystic Fibrosis
Centre for Microbial Diseases and Immunity Research

CANADA

Nouvelle-Écosse
HALIFAX

Finanziato da un ente associato a IRDiRCFunctional Architecture of the CFTR Chloride Channel
Dalhousie University
Department of Physiology & Biophysics

CANADA

Nouvelle-Écosse
HALIFAX

Regulation of CFTR membrane stability and function by VIP
Dalhousie University
Department of Physiology & Biophysics

CANADA

Ontario
TORONTO

Finanziato da un ente associato a IRDiRCEvaluating the Mechanism of Action of Small Molecule Modulators of CFTR
Hospital for Sick Children, Research Institute

CANADA

Ontario
TORONTO

Pathophysiology of Cystic Fibrosis Lung Disease
Hospital for Sick Children, Research Institute
Paediatric Laboratory Medicine

CANADA

Ontario
TORONTO

Finanziato da un ente associato a IRDiRCEnsuring effective newborn screening: The case of cystic fibrosis
University of Toronto
Institute of Health Policy, Management and Evaluation

CANADA

Québec
MONTRÉAL

Screening for abnormalities related to glucose tolerance secondary to cystic fibrosis
Institut de recherches cliniques de Montréal
Plateforme de recherche en obésité, métabolisme et diabète

CANADA

Québec
MONTRÉAL

Finanziato da un ente associato a IRDiRCNeutrophilic inflammation in Cystic Fibrosis
Meakins-Christie Laboratories

FRANCIA

AUVERGNE-RHONE-ALPES
GRENOBLE

Finanziato da un ente associato a IRDiRCB9inPAH: BMP9 as a major regulator of vascular tone in Pulmonary Arterial Hypertension: a promising new therapeutic target - FR
Institut de Biosciences et Biotechnologies de Grenoble (BIG) - CEA
Laboratoire Biologie du Cancer et de l'Infection (BCI) - UMR 1036

FRANCIA

AUVERGNE-RHONE-ALPES
GRENOBLE

FRANCIA

AUVERGNE-RHONE-ALPES
GRENOBLE

Muscular function & cystic fibrosis
Université Joseph Fournier
Laboratoire de Recherche Exercice-Santé

FRANCIA

BOURGOGNE-FRANCHE-COMTE
BESANÇON

FRANCIA

BRETAGNE
BREST

Study of the involvement of pulmonary neuroendocrine cells in cystic fibrosis
CHU de Brest - Hôpital de la Cavale Blanche
Laboratoire de génétique moléculaire et d'histocompatibilité

FRANCIA

CENTRE-VAL DE LOIRE
ORLEANS

Cellular and molecular interactions between proteins E3-14.7K / FIP-1 and microtubules in cystic fibrosis
Centre de biophysique moléculaire
Glycobiologie vectorologie et trafic intracellulaire

FRANCIA

CENTRE-VAL DE LOIRE
TOURS

Induction of neutrophilic traps (NETs) by the inflammation and infectious pulmonary environment of cystic fibrosis
Faculté de pharmacie de Tours
Unité INSERM U618 "Protéases et Vectorisation Pulmonaires"

FRANCIA

CENTRE-VAL DE LOIRE
TOURS

Identification of ligands of human lung cells and production of vectors derived from HPV to lung targeting in cystic fibrosis
Faculté de pharmacie de Tours
Unité INSERM U618 "Protéases et Vectorisation Pulmonaires"

FRANCIA

GRAND-EST
REIMS

Does the mutation of the CFTR contributes to the bone fragility in cystic fibrosis?
Université de Reims - UFR des sciences exactes et naturelles
INSERM UMR-S 926 "Interfaces Biomatériaux / Tissus Hôtes"

FRANCIA

HAUTS-DE-FRANCE
VILLENEUVE D'ASCQ

Regulation and control of the biosynthesis of sialyl Lewisx and 6-sulfo sialyl Lewisx, ligands of Pseudomonas aeruginosa in human bronchial mucosa in cystic fibrosis
Faculté des Sciences et Technologies - Université de Lille
UGSF - Unité de glycobiologie structurale et fonctionnelle

FRANCIA

HAUTS-DE-FRANCE
VILLENEUVE D'ASCQ

Study of the expression and the glycosylation of DMBT1 by the parietal glycoconjugates (LPS and alginate) of Pseudomonas aeruginosa from patients with cystic fibrosis
Faculté des Sciences et Technologies - Université de Lille
UGSF - Unité de glycobiologie structurale et fonctionnelle

FRANCIA

ILE-DE-FRANCE
CRÉTEIL

Contribution to the study of the CFTR interactome: dynamics and role of a CFTR-containing complex in inflammation in cystic fibrosis
Faculté de Médecine de Créteil
Equipe "Immunopathologie rénale et immunomodulation en transplantation"

FRANCIA

ILE-DE-FRANCE
GARCHES

Mycobacterium abscessus - phagocytic cells CFTR-/ - and particular susceptibility of CF patients
CHU Paris IdF Ouest - Hôpital Raymond Poincaré
Service de microbiologie

FRANCIA

ILE-DE-FRANCE
LE PLESSIS-ROBINSON

Finanziato da un ente associato a IRDiRCCoVeR: Contribution of the Vascular Smooth Muscle Cell-associated Type I cytokine receptors to Pulmonary Arterial Hypertension: At the interface between inflammation and pulmonary vascular remodeling
Centre Chirurgical Marie Lannelongue
Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique - Inserm UMR_S 999

FRANCIA

ILE-DE-FRANCE
PARIS

Implementation of non-invasive prenatal diagnosis of rare and severe monogenic diseases
CHU Paris Centre - Hôpital Cochin, Site Cochin
Service de génétique et biologie moléculaires

FRANCIA

ILE-DE-FRANCE
PARIS

Assessment of perfusion pressures on introduced catheter chamber in adult patients with cystic fibrosis
CHU Paris Centre - Hôpital Cochin, Site Cochin
Service de pneumologie - CRCM

FRANCIA

ILE-DE-FRANCE
PARIS

Tracheal malformations in cystic fibrosis: fundamental studies and clinical investigation
CHU Paris Est - Hôpital d'Enfants Armand-Trousseau
Service de pneumologie pédiatrique

FRANCIA

ILE-DE-FRANCE
PARIS

Indications and benefits of nocturnal oxygen therapy in cystic fibrosis
CHU Paris Est - Hôpital d'Enfants Armand-Trousseau
Service de pneumologie pédiatrique

FRANCIA

ILE-DE-FRANCE
PARIS

FRANCIA

ILE-DE-FRANCE
PARIS

Modulation of alveolar macrophage and bronchial epithelial cells function by the antimicrobial/antelastase elafin molecule in cystic fibrosis patients
Faculté de Médecine Paris Diderot Paris 7 - site Bichat
Physiopathologie et Epidémiologie des Maladies respiratoire - INSERM UMR 1152

FRANCIA

ILE-DE-FRANCE
PARIS

FRANCIA

ILE-DE-FRANCE
PARIS

NEUPROCF: new diagnostic and prognostic biomarkers in cystic fibrosis (coordination)
Faculté de médecine Paris-Descartes, Site Necker
Département "Biologie cellulaire" - Equipe "Canalopathies épitheliales: Mucoviscidose et autres maladies"

FRANCIA

ILE-DE-FRANCE
PARIS

Genotype-phenotype study of CFTR from a new model of human respiratory epithelium of cystic fibrosis
Faculté de médecine Paris-Descartes, Site Necker
Département "Biologie cellulaire" - Equipe "Canalopathies épitheliales: Mucoviscidose et autres maladies"

FRANCIA

ILE-DE-FRANCE
PARIS

Validation of the assessment of bone mineralization by quantitative computed tomography in patients with cystic fibrosis
Faculté de médecine Paris-Descartes, Site Necker
Département "Biologie cellulaire" - Equipe "Canalopathies épitheliales: Mucoviscidose et autres maladies"

FRANCIA

ILE-DE-FRANCE
PARIS

Virulence of Mycobacterium abscessus: role of surface glycopeptidolipids in cystic fibrosis
Faculté de médecine Paris-Descartes, Site Necker
Analyse génétique de l'enveloppe mycobactérienne

FRANCIA

ILE-DE-FRANCE
PARIS

Prospective study of the psychopathology of adolescents with cystic fibrosis
Hôpital Necker-Enfants Malades
Unité de pneumo-allergologie pédiatrique

FRANCIA

ILE-DE-FRANCE
PARIS

Three-dimensional structure modeling of CFTR: predicting the impact of mutations and binding sites of markers / potentiators in cystic fibrosis patients
IMPMC - Institut de Minéralogie et de Physique des Milieux Condensés
Protein Structure Prediction

FRANCIA

ILE-DE-FRANCE
VERSAILLES

Highlight CNG cation channels (cyclic nucleotide-gated cation channels) in the bronchial epithelium and bronchiolar airways of human with cystic fibrosis or not
Université de Versailles Saint-Quentin
Laboratoire Mécanismes pharmacologiques et moléculaires de l' obstruction bronchique

FRANCIA

ILE-DE-FRANCE
VILLEJUIF

Finanziato da un ente associato a IRDiRCTransition Platforms: Understanding the Expectations of Parents of Young People with Rare Diseases
CLCC Institut Gustave Roussy
Equipe Epidémiologie des radiations, épidémiologie clinique des cancers et survie

FRANCIA

NOUVELLE AQUITAINE
POITIERS

FRANCIA

OCCITANIE
MONTPELLIER

Measuring the impact of surgery on nasosinusienne ENT symptoms and sleep quality in patients with cystic fibrosis
CHU de Montpellier - Hôpital Arnaud de Villeneuve
Service des maladies respiratoires

FRANCIA

OCCITANIE
MONTPELLIER

DNA glycomimetics to prevent the adherence of Pseudomonas aeruginosa - impact in cystic fibrosis
Faculté de Pharmacie
Département oligonucléotides modifiés

FRANCIA

OCCITANIE
MONTPELLIER

Study of CFTR gene's transcriptional regulation in cystic fibrosis
IURC - Institut Universitaire de Recherche Clinique
Laboratoire de génétique moléculaire

FRANCIA

OCCITANIE
MONTPELLIER

FRANCIA

OCCITANIE
MONTPELLIER

Identification of new regulatory actors in the noncoding regions of CFTR gene: the microRNA and cystic fibrosis
IURC - Institut Universitaire de Recherche Clinique
Laboratoire de génétique moléculaire

FRANCIA

OCCITANIE
MONTPELLIER

Study of virulence factor MGTC and its inhibition by a natural peptide in Pseudomonas aeruginosa and in non-tuberculous mycobacteria - impact in cystic fibrosis
Université Montpellier II
Laboratoire de dynamique des interactions membranaires normales et pathologiques - Case 107

FRANCIA

OCCITANIE
TOULOUSE

Effect of CFTR on the intra-enterocyte cholesterol in patients with cystic fibrosis
CHU de Toulouse - Hôpital Purpan
Département lipoprotéines et médiateurs lipidiques

FRANCIA

PAYS DE LA LOIRE
NANTES

CFTR gene expression in the pulmonary epithelium by targeted gene transfer in cystic fibrosis
Faculté de médecine de Nantes
Physiopathologie et pharmacologie cellulaire et moléculaire

FRANCIA

PAYS DE LA LOIRE
NANTES

Reduced lung inflammation in cystic fibrosis by inhibiting the expression of key genes by RNA interference
Faculté de médecine de Nantes
Physiopathologie et pharmacologie cellulaire et moléculaire

GERMANIA

Baden-Württemberg
HEIDELBERG

COMPERA / COMPERA-KIDS: Prospective registry of newly initiated therapies for Pulmonary Hypertension
Zentrum für Kinder- und Jugendmedizin - Angelika-Lautenschläger-Klinik
Klinik für Kinderheilkunde II - Pädiatrische Kardiologie/Angeborene Herzfehler

GERMANIA

Baden-Württemberg
ULM

The TOPP-2 registry: Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension
Klinik für Kinder- und Jugendmedizin des Universitätsklinikums Ulm
Sektion Pädiatrische Kardiologie

GERMANIA

Berlin
BERLIN

Finanziato da un ente associato a IRDiRCCORD : Collaboration On Rare Diseases
Geschäftsstelle BIH
Berliner Institut für Gesundheitsforschung

GIAPPONE

JAPAN
MIYAGI

GIAPPONE

JAPAN
OSAKA

Finanziato da un ente associato a IRDiRCDevelopment of novel therapeutic strategies for pulmonary arterial hypertension targeting interleukin-2 1
National Cerebral and Cardiovascular Center
Department of Vascular Physiology

IRLANDA

County Cork
CORK

Predicting Response in Disease outcomes in CF using iPSCs for new CFTR Therapies (PREDiCT)
Cork University Hospital
Department of Respiratory Medicine

IRLANDA

County Dublin
DUBLIN

The Role of Exercise in the Management of Cystic Fibrosis
Dublin City University
MedEx Research Laboratory

IRLANDA

County Dublin
DUBLIN

The natural history of cystic fibrosis liver disease - refining the phenotype
Our Lady's Children's Hospital
Gastroenterology Department

IRLANDA

County Dublin
DUBLIN

C-FORMS: Children's Follow up Orkambi Real world MBV Study
Our Lady's Children's Hospital
Gastroenterology Department

IRLANDA

County Dublin
DUBLIN

SHIELD CF - The Study of Host Immunity and Early Lung Disease in Cystic Fibrosis
Our Lady's Children's Hospital
Respirology Department

IRLANDA

County Dublin
DUBLIN

PALM Study: Protease Activity:Lung Measurement in Children with Cystic Fibrosis
Our Lady's Children's Hospital
Respirology Department

IRLANDA

County Dublin
DUBLIN

Cystic Fibrosis Urinary Biomarker Study (CUBS Study)
Our Lady's Children's Hospital
Respirology Department

IRLANDA

County Dublin
DUBLIN

IRLANDA

County Dublin
DUBLIN

The Role of Exosomes in Cystic Fibrosis Airway Pathogenesis (RECAP)
Our Lady's Children's Hospital
Respirology Department

ITALIA

LAZIO
ROMA

Terapia antinfiammatoria con desemetasone intraeritrocitario a lento rilascio nel controllo della flogosi polmonare in soggetti affetti da Fibrosi Cistica
IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO
U.O. di Epatologia, Gastroenterologia e Nutrizione

ITALIA

LAZIO
ROMA

Finanziato da un ente associato a IRDiRCRegistro italiano dei pazienti affetti da fibrosi cistica
ISS - Istituto Superiore di Sanità
Centro Nazionale Malattie Rare

ITALIA

LAZIO
ROMA

ITALIA

LOMBARDIA
MILANO

Finanziato da un ente associato a IRDiRCRescueCFTRpreclinic: Cysteamine for the treatment of cystic fibrosis: a translational research project - IT
IRCCS Ospedale San Raffaele
Centro di Genomica, Bioinformatica e Biostatistica - Unità di Genetica Umana e Molecolare

ITALIA

TOSCANA
SIENA

Studio Genomico mutazionale e funzionale nelle Malformazioni Vascolari per delineare appropriate strategie terapeutiche
Azienda Ospedaliera Universitaria Senese - Policlinico Santa Maria alle Scotte
U.O.C. di Genetica Medica

NORVEGIA

Østlandet
OSLO

Cystic Fibrosis and Fit-to-Fly
Oslo University Hospital, Ullevaal
NSCF - Norsk senter for cystisk fibrose

PORTOGALLO

SUL
LISBOA

Elucidating the role of novel CFTR interactors - new mechanisms in membrane protein trafficking.
Faculdade de Ciências da Universidade de Lisboa
Membrane Protein Disorders Unit

PORTOGALLO

SUL
LISBOA

Diagnosis, Prognosis and Treatment of Cystic Fibrosis
Faculdade de Ciências da Universidade de Lisboa
Membrane Protein Disorders Unit

PORTOGALLO

SUL
LISBOA

Characterization of ER-quality control for the F508del-CFTR protein: potential therapeutic targets for cystic fibrosis
Faculdade de Ciências da Universidade de Lisboa
Membrane Protein Disorders Unit

PORTOGALLO

SUL
LISBOA

Identification of Novel Targets Rescuing of F508del-CFTR Traffic: Mechanism of Action
Faculdade de Ciências da Universidade de Lisboa
Membrane Protein Disorders Unit

PORTOGALLO

SUL
OEIRAS

Biochemical and Structural Studies of UDP-Glucose Dehydrogenases.
Instituto de Tecnologia Química e Biológica
Unidade de Cristalografia Macromolecular

REGNO UNITO; GRAN BRETAGNA

Antrim and Newtownabbey
BELFAST

Parameters to Assess Response to Intra-Venous Antibiotic Treatment for Pulmonary Exacerbations in Cystic Fibrosis (PRIVATE)
Queen's University Belfast
School of Medicine, Dentistry and Biomedical Sciences

REGNO UNITO; GRAN BRETAGNA

Avon
BRISTOL

EUROCARE CF: European coordination action for research in cystic fibrosis (coordination)
University of Bristol
Department of Physiology and Pharmacology

REGNO UNITO; GRAN BRETAGNA

Greater London
LONDON

Air Pollution and Children With Cystic Fibrosis -GB
Queen Mary University of London Headquarters

REGNO UNITO; GRAN BRETAGNA

Greater Manchester
MANCHESTER

REGNO UNITO; GRAN BRETAGNA

Lothian
EDINBURGH

Finanziato da un ente associato a IRDiRCInflammation in Cystic Fibrosis Lung Disease: Defining the Role of Calprotectin
Western General Hospital
Edinburgh Cancer Research Centre

REGNO UNITO; GRAN BRETAGNA

Warwickshire
COVENTRY

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

SVIZZERA

Suisse Alémanique
BERN

Multiple Breath Washout in Children with Cystic Fibrosis: Transition from a Specialised Tool to Clinical Implementation
Inselspital Universitätsspital
Abteilung für pädiatrische Pneumologie und Allergologie

SVIZZERA

Suisse Alémanique
BERN

Prospective Surveillance of Lung Development During Childhood, Adolescence and Adulthood in Healthy and Patients With Cystic Fibrosis
Inselspital Universitätsspital
Abteilung für pädiatrische Pneumologie und Allergologie

SVIZZERA

Suisse Alémanique
BERN

SVIZZERA

Suisse Alémanique
BERN

SVIZZERA

Suisse Romande
GENÈVE

Intercellular signaling in cystic Fibrosis airway innate host defense mechanisms
Centre Médical Universitaire - CMU
Département de physiologie cellulaire et métabolisme

AUSTRIA

WIEN
ADDRESS: NOT PROVIDED - AT

Role of sclerostin in pulmonary arterial hypertension
Institution: Information not provided - AT

GERMANIA

Baden-Württemberg
HEIDELBERG

Yoga in Patients With Fibrosing Interstitial Lung Diseases
Thoraxklinik-Heidelberg gGmbH
Thoraxklinik Heidelberg

GERMANIA

Bayern
MÜNCHEN

Finanziato da un ente associato a IRDiRCHCQ4Surfdefect : Hydroxychloroquine (HCQ) in pediatric ILD -DE-
Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital
Christiane Herzog Ambulanz

SPAGNA

Madrid
MADRID

Finanziato da un ente associato a IRDiRCGenetic-molecular bases of precision medicine in pulmonary arterial hypertension
Hospital Universitario 12 de Octubre
Unidad Multidisciplinar de Hipertensión Pulmonar

SPAGNA

Madrid
MADRID

GENETIC PASSIONHP Project
INGEMM - Instituto de Genética Médica y Molecular (IdiPAZ)
Sección de Genómica Estructural y Funcional

FRANCIA

ILE-DE-FRANCE
LE PLESSIS-ROBINSON

Finanziato da un ente associato a IRDiRCTAMIRAH: Targeting activated mineralocorticoid receptor in Pulmonary Arterial Hypertension: A translational approach towards treatment - FR
Centre Chirurgical Marie Lannelongue
Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique - Inserm UMR_S 999

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

AUSTRIA

WIEN
WIEN

ALARM: Advisory Lead ARDS Respirator Management
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Allgemeine Anästhesie und Intensivmedizin

FRANCIA

AUVERGNE-RHONE-ALPES
ADDRESS: NOT PROVIDED - FR

FRANCIA

AUVERGNE-RHONE-ALPES
BRON

Genetic transmission of familial forms of sarcoidosis
CHU de Lyon HCL - GH Est
Unité Médicale de Génétique des Cancers et des Maladies Multifactorielles

GERMANIA

Berlin
BERLIN

Surface electromyography in patients with Acute Respiratory Distress Syndrome (ARDS)
Charité - Universitätsmedizin Berlin (CBF)
Klinik für Anästhesiologie mit Schwerpunkt operative Intensivmedizin

IRLANDA

County Galway
GALWAY

Development of a nebulised cell based therapy for acute respiratory distress syndrome
National University of Ireland Galway
School of Medicine

PAESI BASSI

Utrecht
NIEUWEGEIN

Genetic predisposition to interstitital lung diseases and disease phenotypes
St. Antonius Ziekenhuis, locatie Nieuwegein
Longcentrum

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCInhaled gm-csf therapy of autoimmune pulmonary alveolar proteinosis
Institution: Information not provided - US

UNGHERIA

Dél-Dunántúl
PECS

AUSTRIA

TIROL
INNSBRUCK

AUSTRIA

TIROL
INNSBRUCK

Finanziato da un ente associato a IRDiRCPersTIgAN: Personalized Treatment in IgA Nephropathy - AT
Medizinische Universität Innsbruck
Universitätsklinik für Innere Medizin IV - Nephrologie und Hypertensiologie

CANADA

Ontario
KINGSTON

Finanziato da un ente associato a IRDiRCIIH-ECC: Idiopathic Infantile Hypercalcemia - European-Canadian Consortium - CA
Queen's University
Department of Biomedical and Molecular Sciences

CANADA

Ontario
TORONTO

FRANCIA

AUVERGNE-RHONE-ALPES
GRENOBLE

USIDNET: modelization of X+CGD chronic granulomatous disease and Nox2 super oxidase mutants in the PLB-985 cell line to study the NADPH oxidase activation process
CHU de Grenoble et des Alpes - Institut de biologie et de pathologie
Centre Diagnostic et Recherche sur la Granulomatose Septique Chronique

FRANCIA

AUVERGNE-RHONE-ALPES
LA TRONCHE

NOX NADPH oxydases in inflammatory response: physiopathological aspects, regulation mechanism and modeling
Université Grenoble Alpes (UGA) - Campus santé
GREPI : Groupe de Recherche et d'Etudes du Processus Inflammatoire

FRANCIA

AUVERGNE-RHONE-ALPES
LA TRONCHE

Validation of a new concept of cell therapy by transfer of proteins in enzymopathies: application to the Chronic septic granulomatosis
Université Grenoble Alpes (UGA) - Campus santé
GREPI : Groupe de Recherche et d'Etudes du Processus Inflammatoire

FRANCIA

CENTRE-VAL DE LOIRE
TOURS

Finanziato da un ente associato a IRDiRCAcoustic Waves and Helium/oxygen for Aerosol Treatment of Idiopathic Pulmonary Fibrosis (IPF)
Faculté de Médecine, Université de Tours François Rabelais
Équipe Inserm 3 : « Aérosolthérapie et biothérapies à visée respiratoire »

FRANCIA

GRAND-EST
STRASBOURG CEDEX

Finanziato da un ente associato a IRDiRCRare Invisible Disease and Schooling of Children
ESPE de Strasbourg
Equipe Apprentissages, pratiques d'enseignement et d'éducation

FRANCIA

ILE-DE-FRANCE
CRÉTEIL

Surfactant deficiencies in chronic lung diseases in children
Centre Hospitalier Intercommunal de Créteil
Service de pédiatrie - Hôpital de jour

FRANCIA

ILE-DE-FRANCE
PARIS

ERADAS and ERAFI: development and validation of the scores of activity and functional impairment in juvenile spondylitis
Hôpital Necker-Enfants Malades
Développement normal et pathologique du système immunitaire

GERMANIA

Berlin
ADDRESS: NOT PROVIDED - DE

Finanziato da un ente associato a IRDiRCICON: Analysis of uveitism manifestation and outcome
Institution: Information not provided - DE

GERMANIA

Berlin
BERLIN

JuMBO: Juvenile Arthritis - Methotrexate / Biologics long-term Observation
Deutsches Rheuma-Forschungszentrum Berlin
Forschungsbereich Epidemiologie

GERMANIA

Nordrhein-Westfalen
MÜNSTER

Finanziato da un ente associato a IRDiRCICON: Biosample collection and biomarker analysis
Universitätsklinikum Münster
Klinik für Kinder- und Jugendmedizin - Pädiatrische Rheumatologie und Immunologie

GERMANIA

Nordrhein-Westfalen
SANKT AUGUSTIN

GIAPPONE

JAPAN
KYOTO

Finanziato da un ente associato a IRDiRCDiscovery of novel therapeutic approach for Nakajo-Nishimura syndrome and Blau syndrome
Center for iPS Cell Research and Application, Kyoto University
Department of Clinical Application

IRLANDA

County Dublin
DUBLIN

IRLANDA

County Dublin
DUBLIN

Urinary sCD163 as a biomarker in crescentic glomerulonephritis
Trinity College Dublin
Trinity Translational Medicine Institute

IRLANDA

County Galway
GALWAY

ITALIA

LOMBARDIA
MILANO

Patogenesi e terapia della malattia granulomatosa cronica mediante trasferimento genico in cellule staminali ematopoietiche
Istituto San Raffaele Telethon per la Terapia Genica - TIGET
Unità di Ricerca Clinica

ITALIA

LOMBARDIA
MONZA

Valutazione dello stato nutrizionale nella fibrosi polmonare idiopatica: uno studio pilota
ASST Monza - Ospedale San Gerardo
Dipartimento Cardio-Toraco-Vascolare

REGNO UNITO; GRAN BRETAGNA

Greater London
LONDON

REGNO UNITO; GRAN BRETAGNA

Greater London
LONDON

SPAGNA

Cantabria
SANTANDER

Finanziato da un ente associato a IRDiRCCharacterization of molecular bases of IgA-mediated vasculitis
IDIVAL: Instituto de Investigación Marqués de Valdecilla
Grupo de Epidemiología genética y arterioesclerosis en enfermedades inflamatorias sistémicas

SPAGNA

Cataluña
BARCELONA

Finanziato da un ente associato a IRDiRCStudy of mechanisms of progression to pulmonary fibrosis in patients with hypersensitivity pneumonitis
Vall d'Hebron Institut de Recerca VHIR
Grupo de investigación en neumología

SPAGNA

Cataluña
L'HOSPITALET DE LLOBREGAT

Finanziato da un ente associato a IRDiRCCharacterization of telomeric pulmonary fibrosis and its biological regulation
Hospital Universitari de Bellvitge
Servicio de Neumología

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCJuvenile myositis
Institution: Information not provided - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCNeuro-ophthalmic mechanisms of disease
Institution: Information not provided - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCTargeting jak3 in the treatment of autoimmune disease
Institution: Information not provided - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCAcid sphingomyelinase and niemann-pick disease
Institution: Information not provided - US

SVEZIA

Region Stockholm
STOCKHOLM

SVIZZERA

Suisse Alémanique
BASEL

AUSTRIA

WIEN
WIEN

Finanziato da un ente associato a IRDiRCRELENT: RELapses prevENTion in chronic autoimmune disease: common mechanisms and co-morbidities - AT
Medizinische Universität Wien
Klinisches Institut für Pathologie

AUSTRIA

WIEN
WIEN

From AAV (ANCA-associated vasculitis) to chronic kidney disease - contribution of TenascinC
Medizinische Universität Wien
Klinisches Institut für Pathologie

AUSTRIA

WIEN
WIEN

Finanziato da un ente associato a IRDiRCExtracellular Vesicles (EV) as markers of active disease in AAV (ANCA-associated vasculitis) - AT
Medizinische Universität Wien
Klinisches Institut für Pathologie

GIAPPONE

JAPAN
CHIBA

Finanziato da un ente associato a IRDiRCPathological analysis and development ofan innovative therapeutic agent ofniemann-pick disease type C
Graduate School of Pharmaceutical Sciences, Chiba University
Laboratory of Chemical Pharmacology

GIAPPONE

JAPAN
KUMAMOTO

Finanziato da un ente associato a IRDiRCDeveloping new drugs for Niemann-Pick disease type C
Institute of Molecular Embryology and Genetics, Kumamoto University
Department of Cell Modulation

GIAPPONE

JAPAN
OSAKA

Finanziato da un ente associato a IRDiRCDeveloping the disease specific therapy for ANCA-associated vasculitis focused on immune regulatory factors in neutrophils
Osaka University Graduate School of Medicine
Department of Respiratory Medicine and Clinical Immunology

IRLANDA

County Dublin
DUBLIN

AVERT: Autoimmunity Relapse Prediction Using Multiple Parallel Data Sources
Trinity College Dublin
Trinity Translational Medicine Institute

ITALIA

FRIULI VENEZIA GIULIA
UDINE

Studio del ruolo del ripiegamento proteico nella patogenesi della malattia di Niemann-Pick tipo C: un possibile target terapeutico
Azienda Ospedaliero-Universitaria "Santa Maria della Misericordia" di Udine
Centro di Coordinamento Regionale per le Malattie Rare

ITALIA

FRIULI VENEZIA GIULIA
UDINE

Screening della malattia di Niemann Pick tipo C tra pazienti affetti con malattia psichiatrica con eziologia sconosciuta
Azienda Ospedaliero-Universitaria "Santa Maria della Misericordia" di Udine
Centro di Coordinamento Regionale per le Malattie Rare

ITALIA

LAZIO
ROMA

Finanziato da un ente associato a IRDiRCTargeting adenosine tone in Niemann Pick type C Disease
ISS - Istituto Superiore di Sanità
Centro Nazionale per la Ricerca e la Valutazione preclinica e clinica dei Farmaci

ITALIA

PUGLIA
BARI

Fisiopatologia della Vasculite Crioglobulinemica HCV-correlata: analisi molecolare, immunologica e clinica
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Unità di Epatologia - Sezione di Medicina Interna e Oncologia Clinica

ITALIA

TOSCANA
PISA

Studio dei meccanismi cellulari della malattia di Niemann-Pick di tipo C e identificazione di terapie neuroprotettive
Fondazione "Gabriele Monasterio" - Consiglio Nazionale delle Ricerche CNR
Area della Ricerca

PORTOGALLO

NORTE
PORTO

The sorting and trafficking of lysosomal proteins through M6P independent pathways: molecular, biochemical and functional studies
Instituto Nacional de Saúde Dr. Ricardo Jorge - Porto
Unidade de Investigação & Desenvolvimento; Departamento de Genética

REGNO UNITO; GRAN BRETAGNA

Glasgow
GLASGOW

Finanziato da un ente associato a IRDiRCHarnessing the power of integrated data to investigate environmental exposures on ANCA vasculitis risk , an unbiased approach -GB
Institute of Infection, Immunity and Inflammation, University of Glasgow
Institute of Infection, Immunity and Inflammation

SPAGNA

Cataluña
BARCELONA

Corrective therapy of splicing by antisense oligonucleotides for Niemann-Pick disease type C: pre-clinical study in a murine model
Universitat de Barcelona. Facultat de Biologia
Departamento de genética molecular humana

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCTherapeutics for rare and neglected diseases - science
Institution: Information not provided - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCDevelopment of neurosteroids for lysosomal storage disorders
Institution: Information not provided - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCGenetic analysis of complex inflammatory disorders
Institution: Information not provided - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCGenetic and genomic analysis of niemann pick type c1 disease
Institution: Information not provided - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCNovel regulators of inflammatory arthritis and bone erosion
Institution: Information not provided - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCPathogenesis of behcet's disease and still's disease
Institution: Information not provided - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCClinical investigations of niemann-pick disease; type c
Institution: Information not provided - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Finanziato da un ente associato a IRDiRCInborn errors of cholesterol synthesis
Institution: Information not provided - US

FRANCIA

ILE-DE-FRANCE
PARIS

Model contribution in the microeconomic assessment of therapeutic strategies in Wegener granulomatosis
CHU Paris Centre - Hôpital Cochin, Site Cochin
Service de Santé publique : Gestion des risques et qualité

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

STATI UNITI

Washington
ADDRESS: NOT PROVIDED - US

Progetti di ricerca multicentrici