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Gefinancierd door een IRDiRC-lid = Member of a ERN =

Onderzoeksprojecten

BELGIË

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

BELGIË

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

FLONAMUC: Epidemiology of the Nasal Flora at the Reference Center for Cystic Fibrosis of Queen Fabiola Children's University Hospital
Hôpital Universitaire des Enfants Reine Fabiola - HUDERF
Service de Pneumologie-Allergologie

BELGIË

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

MucoSWEATomics New Markers of CFTR Function in Sweat: Value for Diagnosis and Efficacy of Target Therapies
Université Catholique de Louvain (UCL)
Louvain centre for Toxicology and Applied Pharmacology

BELGIË

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUXELLES

Efflux as a mechanism of intrinsic and acquired resistance to antibiotics in Achromobacter xylosoxidans
Cellular and Molecular Pharmacology Unit, Louvain Drug Research Institute, UCL
Cellular and Molecular Pharmacology Unit

BELGIË

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUXELLES

Development of CFTR-stabilizers as therapeutic for cystic fibrosis
Structure et Fonction des Membranes Biologiques
Laboratoire Structure et Fonction des Membranes Biologiques

BELGIË

OOST-VLAANDEREN
GENT

Ontwikkeling van een gepersonaliseerde aanpak voor het testen van gevoeligheid aan antibiotica
LPM Pharmaceutical Microbiology, Universiteit Gent
LPM Laboratory of Pharmaceutical Microbiology

BELGIË

VLAAMS BRABANT
LEUVEN

Ontwikkeling van therapieën voor zeldzame mutaties die ernstige mucoviscidose veroorzaken
Center for molecular medicine, Division of Molecular Virology and Gene Therapy
Molecular Virology and Gene Therapy

BELGIË

VLAAMS BRABANT
LEUVEN

Evaluatie van de CFTR functie in organoïden ('minidarmpjes') verkregen uit rectale biopsieën van mucoviscidosepatiënten
UZ Leuven - Campus Gasthuisberg
Dienst Kindergeneeskunde/Department of Pediatrics

BELGIË

VLAAMS BRABANT
LEUVEN

CANADA

Colombie-Britannique
VANCOUVER

Mechanisms of Hyperinfammation in Cystic Fibrosis
Centre for Microbial Diseases and Immunity Research

CANADA

Nouvelle-Écosse
HALIFAX

Gefinancierd door een IRDiRC-lidFunctional Architecture of the CFTR Chloride Channel
Dalhousie University
Department of Physiology & Biophysics

CANADA

Nouvelle-Écosse
HALIFAX

Regulation of CFTR membrane stability and function by VIP
Dalhousie University
Department of Physiology & Biophysics

CANADA

Ontario
TORONTO

Gefinancierd door een IRDiRC-lidEvaluating the Mechanism of Action of Small Molecule Modulators of CFTR
Hospital for Sick Children, Research Institute

CANADA

Ontario
TORONTO

Pathophysiology of Cystic Fibrosis Lung Disease
Hospital for Sick Children, Research Institute
Paediatric Laboratory Medicine

CANADA

Ontario
TORONTO

Gefinancierd door een IRDiRC-lidEnsuring effective newborn screening: The case of cystic fibrosis
University of Toronto
Institute of Health Policy, Management and Evaluation

CANADA

Québec
MONTRÉAL

Screening for abnormalities related to glucose tolerance secondary to cystic fibrosis
Institut de recherches cliniques de Montréal
Plateforme de recherche en obésité, métabolisme et diabète

CANADA

Québec
MONTRÉAL

Gefinancierd door een IRDiRC-lidNeutrophilic inflammation in Cystic Fibrosis
Meakins-Christie Laboratories

DUITSLAND

Baden-Württemberg
HEIDELBERG

COMPERA / COMPERA-KIDS: Prospective registry of newly initiated therapies for Pulmonary Hypertension
Zentrum für Kinder- und Jugendmedizin - Angelika-Lautenschläger-Klinik
Klinik für Kinderheilkunde II - Pädiatrische Kardiologie/Angeborene Herzfehler

DUITSLAND

Baden-Württemberg
ULM

The TOPP-2 registry: Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension
Klinik für Kinder- und Jugendmedizin des Universitätsklinikums Ulm
Sektion Pädiatrische Kardiologie

DUITSLAND

Berlin
BERLIN

Gefinancierd door een IRDiRC-lidCORD : Collaboration On Rare Diseases
Geschäftsstelle BIH
Berliner Institut für Gesundheitsforschung

DUITSLAND

Niedersachsen
HANNOVER

FRANKRIJK

AUVERGNE-RHONE-ALPES
GRENOBLE

Gefinancierd door een IRDiRC-lidB9inPAH: BMP9 as a major regulator of vascular tone in Pulmonary Arterial Hypertension: a promising new therapeutic target - FR
Institut de Biosciences et Biotechnologies de Grenoble (BIG) - CEA
Laboratoire Biologie du Cancer et de l'Infection (BCI) - UMR 1036

FRANKRIJK

AUVERGNE-RHONE-ALPES
GRENOBLE

FRANKRIJK

AUVERGNE-RHONE-ALPES
GRENOBLE

Muscular function & cystic fibrosis
Université Joseph Fournier
Laboratoire de Recherche Exercice-Santé

FRANKRIJK

BOURGOGNE-FRANCHE-COMTE
BESANÇON

FRANKRIJK

BRETAGNE
BREST

Study of the involvement of pulmonary neuroendocrine cells in cystic fibrosis
CHU de Brest - Hôpital de la Cavale Blanche
Laboratoire de génétique moléculaire et d'histocompatibilité

FRANKRIJK

CENTRE-VAL DE LOIRE
ORLEANS

Cellular and molecular interactions between proteins E3-14.7K / FIP-1 and microtubules in cystic fibrosis
Centre de biophysique moléculaire
Glycobiologie vectorologie et trafic intracellulaire

FRANKRIJK

CENTRE-VAL DE LOIRE
TOURS

Induction of neutrophilic traps (NETs) by the inflammation and infectious pulmonary environment of cystic fibrosis
Faculté de pharmacie de Tours
Unité INSERM U618 "Protéases et Vectorisation Pulmonaires"

FRANKRIJK

CENTRE-VAL DE LOIRE
TOURS

Identification of ligands of human lung cells and production of vectors derived from HPV to lung targeting in cystic fibrosis
Faculté de pharmacie de Tours
Unité INSERM U618 "Protéases et Vectorisation Pulmonaires"

FRANKRIJK

GRAND-EST
REIMS

Does the mutation of the CFTR contributes to the bone fragility in cystic fibrosis?
Université de Reims - UFR des sciences exactes et naturelles
INSERM UMR-S 926 "Interfaces Biomatériaux / Tissus Hôtes"

FRANKRIJK

HAUTS-DE-FRANCE
VILLENEUVE D'ASCQ

Regulation and control of the biosynthesis of sialyl Lewisx and 6-sulfo sialyl Lewisx, ligands of Pseudomonas aeruginosa in human bronchial mucosa in cystic fibrosis
Faculté des Sciences et Technologies - Université de Lille
UGSF - Unité de glycobiologie structurale et fonctionnelle

FRANKRIJK

HAUTS-DE-FRANCE
VILLENEUVE D'ASCQ

Study of the expression and the glycosylation of DMBT1 by the parietal glycoconjugates (LPS and alginate) of Pseudomonas aeruginosa from patients with cystic fibrosis
Faculté des Sciences et Technologies - Université de Lille
UGSF - Unité de glycobiologie structurale et fonctionnelle

FRANKRIJK

ILE-DE-FRANCE
CRÉTEIL

Contribution to the study of the CFTR interactome: dynamics and role of a CFTR-containing complex in inflammation in cystic fibrosis
Faculté de Médecine de Créteil
Equipe "Immunopathologie rénale et immunomodulation en transplantation"

FRANKRIJK

ILE-DE-FRANCE
GARCHES

Mycobacterium abscessus - phagocytic cells CFTR-/ - and particular susceptibility of CF patients
CHU Paris IdF Ouest - Hôpital Raymond Poincaré
Service de microbiologie

FRANKRIJK

ILE-DE-FRANCE
LE PLESSIS-ROBINSON

Gefinancierd door een IRDiRC-lidCoVeR: Contribution of the Vascular Smooth Muscle Cell-associated Type I cytokine receptors to Pulmonary Arterial Hypertension: At the interface between inflammation and pulmonary vascular remodeling
Centre Chirurgical Marie Lannelongue
Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique - Inserm UMR_S 999

FRANKRIJK

ILE-DE-FRANCE
PARIS

Implementation of non-invasive prenatal diagnosis of rare and severe monogenic diseases
CHU Paris Centre - Hôpital Cochin, Site Cochin
Service de génétique et biologie moléculaires

FRANKRIJK

ILE-DE-FRANCE
PARIS

Assessment of perfusion pressures on introduced catheter chamber in adult patients with cystic fibrosis
CHU Paris Centre - Hôpital Cochin, Site Cochin
Service de pneumologie - CRCM

FRANKRIJK

ILE-DE-FRANCE
PARIS

Tracheal malformations in cystic fibrosis: fundamental studies and clinical investigation
CHU Paris Est - Hôpital d'Enfants Armand-Trousseau
Service de pneumologie pédiatrique

FRANKRIJK

ILE-DE-FRANCE
PARIS

Indications and benefits of nocturnal oxygen therapy in cystic fibrosis
CHU Paris Est - Hôpital d'Enfants Armand-Trousseau
Service de pneumologie pédiatrique

FRANKRIJK

ILE-DE-FRANCE
PARIS

FRANKRIJK

ILE-DE-FRANCE
PARIS

Modulation of alveolar macrophage and bronchial epithelial cells function by the antimicrobial/antelastase elafin molecule in cystic fibrosis patients
Faculté de Médecine Paris Diderot Paris 7 - site Bichat
Physiopathologie et Epidémiologie des Maladies respiratoire - INSERM UMR 1152

FRANKRIJK

ILE-DE-FRANCE
PARIS

FRANKRIJK

ILE-DE-FRANCE
PARIS

NEUPROCF: new diagnostic and prognostic biomarkers in cystic fibrosis (coordination)
Faculté de médecine Paris-Descartes, Site Necker
Département "Biologie cellulaire" - Equipe "Canalopathies épitheliales: Mucoviscidose et autres maladies"

FRANKRIJK

ILE-DE-FRANCE
PARIS

Genotype-phenotype study of CFTR from a new model of human respiratory epithelium of cystic fibrosis
Faculté de médecine Paris-Descartes, Site Necker
Département "Biologie cellulaire" - Equipe "Canalopathies épitheliales: Mucoviscidose et autres maladies"

FRANKRIJK

ILE-DE-FRANCE
PARIS

Validation of the assessment of bone mineralization by quantitative computed tomography in patients with cystic fibrosis
Faculté de médecine Paris-Descartes, Site Necker
Département "Biologie cellulaire" - Equipe "Canalopathies épitheliales: Mucoviscidose et autres maladies"

FRANKRIJK

ILE-DE-FRANCE
PARIS

Virulence of Mycobacterium abscessus: role of surface glycopeptidolipids in cystic fibrosis
Faculté de médecine Paris-Descartes, Site Necker
Analyse génétique de l'enveloppe mycobactérienne

FRANKRIJK

ILE-DE-FRANCE
PARIS

Prospective study of the psychopathology of adolescents with cystic fibrosis
Hôpital Necker-Enfants Malades
Unité de pneumo-allergologie pédiatrique

FRANKRIJK

ILE-DE-FRANCE
PARIS

Three-dimensional structure modeling of CFTR: predicting the impact of mutations and binding sites of markers / potentiators in cystic fibrosis patients
IMPMC - Institut de Minéralogie et de Physique des Milieux Condensés
Protein Structure Prediction

FRANKRIJK

ILE-DE-FRANCE
VERSAILLES

Highlight CNG cation channels (cyclic nucleotide-gated cation channels) in the bronchial epithelium and bronchiolar airways of human with cystic fibrosis or not
Université de Versailles Saint-Quentin
Laboratoire Mécanismes pharmacologiques et moléculaires de l' obstruction bronchique

FRANKRIJK

ILE-DE-FRANCE
VILLEJUIF

Gefinancierd door een IRDiRC-lidTransition Platforms: Understanding the Expectations of Parents of Young People with Rare Diseases
CLCC Institut Gustave Roussy
Equipe Epidémiologie des radiations, épidémiologie clinique des cancers et survie

FRANKRIJK

NOUVELLE AQUITAINE
POITIERS

FRANKRIJK

OCCITANIE
MONTPELLIER

Measuring the impact of surgery on nasosinusienne ENT symptoms and sleep quality in patients with cystic fibrosis
CHU de Montpellier - Hôpital Arnaud de Villeneuve
Service des maladies respiratoires

FRANKRIJK

OCCITANIE
MONTPELLIER

DNA glycomimetics to prevent the adherence of Pseudomonas aeruginosa - impact in cystic fibrosis
Faculté de Pharmacie
Département oligonucléotides modifiés

FRANKRIJK

OCCITANIE
MONTPELLIER

Study of CFTR gene's transcriptional regulation in cystic fibrosis
IURC - Institut Universitaire de Recherche Clinique
Laboratoire de génétique moléculaire

FRANKRIJK

OCCITANIE
MONTPELLIER

FRANKRIJK

OCCITANIE
MONTPELLIER

Identification of new regulatory actors in the noncoding regions of CFTR gene: the microRNA and cystic fibrosis
IURC - Institut Universitaire de Recherche Clinique
Laboratoire de génétique moléculaire

FRANKRIJK

OCCITANIE
MONTPELLIER

Study of virulence factor MGTC and its inhibition by a natural peptide in Pseudomonas aeruginosa and in non-tuberculous mycobacteria - impact in cystic fibrosis
Université Montpellier II
Laboratoire de dynamique des interactions membranaires normales et pathologiques - Case 107

FRANKRIJK

OCCITANIE
TOULOUSE

Effect of CFTR on the intra-enterocyte cholesterol in patients with cystic fibrosis
CHU de Toulouse - Hôpital Purpan
Département lipoprotéines et médiateurs lipidiques

FRANKRIJK

PAYS DE LA LOIRE
NANTES

CFTR gene expression in the pulmonary epithelium by targeted gene transfer in cystic fibrosis
Faculté de médecine de Nantes
Physiopathologie et pharmacologie cellulaire et moléculaire

FRANKRIJK

PAYS DE LA LOIRE
NANTES

Reduced lung inflammation in cystic fibrosis by inhibiting the expression of key genes by RNA interference
Faculté de médecine de Nantes
Physiopathologie et pharmacologie cellulaire et moléculaire

IERLAND

County Cork
CORK

Predicting Response in Disease outcomes in CF using iPSCs for new CFTR Therapies (PREDiCT)
Cork University Hospital
Department of Respiratory Medicine

IERLAND

County Dublin
DUBLIN

The natural history of cystic fibrosis liver disease - refining the phenotype
Children's Health Ireland @ Crumlin
Gastroenterology Department

IERLAND

County Dublin
DUBLIN

C-FORMS: Children's Follow up Orkambi Real world MBV Study
Children's Health Ireland @ Crumlin
Gastroenterology Department

IERLAND

County Dublin
DUBLIN

SHIELD CF - The Study of Host Immunity and Early Lung Disease in Cystic Fibrosis
Children's Health Ireland @ Crumlin
Respirology Department

IERLAND

County Dublin
DUBLIN

C-FORMS: Children's Follow up Orkambi Real world MBV Study
Children's Health Ireland @ Crumlin
Respirology Department

IERLAND

County Dublin
DUBLIN

PALM Study: Protease Activity:Lung Measurement in Children with Cystic Fibrosis
Children's Health Ireland @ Crumlin
Respirology Department

IERLAND

County Dublin
DUBLIN

Cystic Fibrosis Urinary Biomarker Study (CUBS Study)
Children's Health Ireland @ Crumlin
Respirology Department

IERLAND

County Dublin
DUBLIN

Predicting Response in Disease outcomes in CF using iPSCs for new CFTR Therapies (PREDiCT)
Children's Health Ireland @ Crumlin
Respirology Department

IERLAND

County Dublin
DUBLIN

IERLAND

County Dublin
DUBLIN

The Role of Exosomes in Cystic Fibrosis Airway Pathogenesis (RECAP)
Children's Health Ireland @ Crumlin
Respirology Department

IERLAND

County Dublin
DUBLIN

Predicting Response in Disease outcomes in CF using iPSCs for new CFTR Therapies (PREDiCT)
Children's Health Ireland @ Temple Street
Cystic Fibrosis Clinic

IERLAND

County Dublin
DUBLIN

SHIELD CF - The Study of Host Immunity and Early Lung Disease in Cystic Fibrosis
Children's Health Ireland @Tallaght
Specialist Cystic Fibrosis Centre

IERLAND

County Dublin
DUBLIN

C-FORMS: Children's Follow up Orkambi Real world MBV Study
Children's Health Ireland @Tallaght
Specialist Cystic Fibrosis Centre

IERLAND

County Dublin
DUBLIN

Cystic Fibrosis Urinary Biomarker Study (CUBS Study)
Children's Health Ireland @Tallaght
Specialist Cystic Fibrosis Centre

IERLAND

County Dublin
DUBLIN

Predicting Response in Disease outcomes in CF using iPSCs for new CFTR Therapies (PREDiCT)
Children's Health Ireland @Tallaght
Specialist Cystic Fibrosis Centre

IERLAND

County Dublin
DUBLIN

The Role of Exercise in the Management of Cystic Fibrosis
Dublin City University
MedEx Research Laboratory

IERLAND

County Dublin
DUBLIN

The natural history of cystic fibrosis liver disease - refining the phenotype
The Catherine McAuley Education & Research Centre
UCD School of Medicine

IERLAND

County Limerick
LIMERICK

SHIELD CF - The Study of Host Immunity and Early Lung Disease in Cystic Fibrosis
University Hospital Limerick
Cystic Fibrosis Clinic

IERLAND

County Limerick
LIMERICK

C-FORMS: Children's Follow up Orkambi Real world MBV Study
University Hospital Limerick
Cystic Fibrosis Clinic

IERLAND

County Limerick
LIMERICK

Cystic Fibrosis Urinary Biomarker Study (CUBS Study)
University Hospital Limerick
Cystic Fibrosis Clinic

IERLAND

County Limerick
LIMERICK

ITALIË

LAZIO
ROMA

Anti-inflammatory therapy with dexamethasone slow release in the control of lung inflammation in patients with Cystic Fibrosis
IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO
U.O. di Epatologia, Gastroenterologia e Nutrizione

ITALIË

LAZIO
ROMA

Gefinancierd door een IRDiRC-lidItalian National Cystic Fibrosis Patient's Registry
ISS - Istituto Superiore di Sanità
Centro Nazionale Malattie Rare

ITALIË

LAZIO
ROMA

Gefinancierd door een IRDiRC-lidImproving quality standards in Italian laboratories performing genetic testing for rare diseases
ISS - Istituto Superiore di Sanità
Centro Nazionale Malattie Rare

ITALIË

LOMBARDIA
MILANO

Gefinancierd door een IRDiRC-lidRescueCFTRpreclinic: Cysteamine for the treatment of cystic fibrosis: a translational research project - IT
IRCCS Ospedale San Raffaele
Centro di Genomica, Bioinformatica e Biostatistica - Unità di Genetica Umana e Molecolare

ITALIË

TOSCANA
SIENA

Mutational and functional genomic study in Vascular Malformations to delineate appropriate therapeutic strategies
Azienda Ospedaliera Universitaria Senese - Policlinico Santa Maria alle Scotte
U.O.C. di Genetica Medica

JAPAN

JAPAN
MIYAGI

JAPAN

JAPAN
OSAKA

Gefinancierd door een IRDiRC-lidDevelopment of novel therapeutic strategies for pulmonary arterial hypertension targeting interleukin-2 1
National Cerebral and Cardiovascular Center
Department of Vascular Physiology

NOORWEGEN

Østlandet
OSLO

Cystic Fibrosis and Fit-to-Fly
Oslo University Hospital, Ullevaal
NSCF - Norsk senter for cystisk fibrose

OOSTENRIJK

WIEN
WIEN

Lung microbiome for screening imminent exacerbation in CF (cystic fibrosis)
Medizinische Universität Wien
Forschungslabor Infektionsbiologie

PORTUGAL

SUL
LISBOA

Elucidating the role of novel CFTR interactors - new mechanisms in membrane protein trafficking.
Faculdade de Ciências da Universidade de Lisboa
Membrane Protein Disorders Unit

PORTUGAL

SUL
LISBOA

Diagnosis, Prognosis and Treatment of Cystic Fibrosis
Faculdade de Ciências da Universidade de Lisboa
Membrane Protein Disorders Unit

PORTUGAL

SUL
LISBOA

Characterization of ER-quality control for the F508del-CFTR protein: potential therapeutic targets for cystic fibrosis
Faculdade de Ciências da Universidade de Lisboa
Membrane Protein Disorders Unit

PORTUGAL

SUL
LISBOA

Identification of Novel Targets Rescuing of F508del-CFTR Traffic: Mechanism of Action
Faculdade de Ciências da Universidade de Lisboa
Membrane Protein Disorders Unit

PORTUGAL

SUL
OEIRAS

Biochemical and Structural Studies of UDP-Glucose Dehydrogenases.
Instituto de Tecnologia Química e Biológica
Unidade de Cristalografia Macromolecular

SPANJE

Cataluña
L'HOSPITALET DE LLOBREGAT

Gefinancierd door een IRDiRC-lidImproving diagnostic accuracy and therapeutic perspectives in interstitial lung diseases
IDIBELL - Instituto de Investigación Biomédica de Bellvitge
Grupo de Investigación en Neumología

SPANJE

Cataluña
SABADELL

Gefinancierd door een IRDiRC-lidImpact of viral respiratory infection on the gut-lung axis microbiome in cystic fibrosis
Corporación Sanitaria Parc Taulí. Hospital de Sabadell
Servicio de neumología

VERENIGD KONINKRIJK

Antrim and Newtownabbey
BELFAST

Parameters to Assess Response to Intra-Venous Antibiotic Treatment for Pulmonary Exacerbations in Cystic Fibrosis (PRIVATE)
Queen's University Belfast
School of Medicine, Dentistry and Biomedical Sciences

VERENIGD KONINKRIJK

Avon
BRISTOL

EUROCARE CF: European coordination action for research in cystic fibrosis (coordination)
University of Bristol
Department of Physiology and Pharmacology

VERENIGD KONINKRIJK

Greater London
LONDON

Air Pollution and Children With Cystic Fibrosis -GB
Queen Mary University of London Headquarters

VERENIGD KONINKRIJK

Greater Manchester
MANCHESTER

VERENIGD KONINKRIJK

Lothian
EDINBURGH

Gefinancierd door een IRDiRC-lidInflammation in Cystic Fibrosis Lung Disease: Defining the Role of Calprotectin
Western General Hospital
Edinburgh Cancer Research Centre

VERENIGD KONINKRIJK

Warwickshire
COVENTRY

ZWITSERLAND

Suisse Alémanique
BERN

Multiple Breath Washout in Children with Cystic Fibrosis: Transition from a Specialised Tool to Clinical Implementation
Inselspital Universitätsspital
Abteilung für pädiatrische Pneumologie und Allergologie

ZWITSERLAND

Suisse Alémanique
BERN

Prospective Surveillance of Lung Development During Childhood, Adolescence and Adulthood in Healthy and Patients With Cystic Fibrosis
Inselspital Universitätsspital
Abteilung für pädiatrische Pneumologie und Allergologie

ZWITSERLAND

Suisse Alémanique
BERN

ZWITSERLAND

Suisse Romande
GENÈVE

Intercellular signaling in cystic Fibrosis airway innate host defense mechanisms
Centre Médical Universitaire - CMU
Département de physiologie cellulaire et métabolisme

DUITSLAND

Baden-Württemberg
HEIDELBERG

Yoga in Patients With Fibrosing Interstitial Lung Diseases
Thoraxklinik-Heidelberg gGmbH
Thoraxklinik Heidelberg

DUITSLAND

Bayern
MÜNCHEN

Gefinancierd door een IRDiRC-lidHCQ4Surfdefect : Hydroxychloroquine (HCQ) in pediatric ILD -DE-
Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital
Christiane Herzog Ambulanz

OOSTENRIJK

WIEN
ADDRESS: NOT PROVIDED - AT

Role of sclerostin in pulmonary arterial hypertension
Institution: Information not provided - AT

SPANJE

Madrid
MADRID

Gefinancierd door een IRDiRC-lidGenetic-molecular bases of precision medicine in pulmonary arterial hypertension
Hospital Universitario 12 de Octubre
Unidad Multidisciplinar de Hipertensión Pulmonar

SPANJE

Madrid
MADRID

GENETIC PASSIONHP Project
INGEMM - Instituto de Genética Médica y Molecular (IdiPAZ)
Sección de Genómica Estructural y Funcional

FRANKRIJK

ILE-DE-FRANCE
LE PLESSIS-ROBINSON

Gefinancierd door een IRDiRC-lidTAMIRAH: Targeting activated mineralocorticoid receptor in Pulmonary Arterial Hypertension: A translational approach towards treatment - FR
Centre Chirurgical Marie Lannelongue
Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique - Inserm UMR_S 999

SPANJE

Madrid
MADRID

Gefinancierd door een IRDiRC-lidRole of hypoxia and inflammation in the dysfunction of endothelial progenitor cells in pediatric pulmonary hypertension
Universidad Complutense de Madrid. Facultad de Medicina
Departamento de Farmacología y Toxicología

USA

Washington
ADDRESS: NOT PROVIDED - US

DUITSLAND

Berlin
BERLIN

Surface electromyography in patients with Acute Respiratory Distress Syndrome (ARDS)
Charité - Universitätsmedizin Berlin (CBF)
Klinik für Anästhesiologie mit Schwerpunkt operative Intensivmedizin

FRANKRIJK

AUVERGNE-RHONE-ALPES
ADDRESS: NOT PROVIDED - FR

FRANKRIJK

AUVERGNE-RHONE-ALPES
BRON

Genetic transmission of familial forms of sarcoidosis
CHU de Lyon HCL - GH Est
Unité Médicale de Génétique des Cancers et des Maladies Multifactorielles

FRANKRIJK

AUVERGNE-RHONE-ALPES
BRON

Genetic transmission of familial forms of sarcoidosis
CHU de Lyon HCL - GH Est-Hôpital Louis Pradel
Service de pneumologie

HONGARIJE

Dél-Dunántúl
PECS

IERLAND

County Galway
GALWAY

Development of a nebulised cell based therapy for acute respiratory distress syndrome
National University of Ireland Galway
School of Medicine

NEDERLAND

Utrecht
NIEUWEGEIN

Genetische predispositie tot interstitiele longziekten en ziektevormen
St. Antonius Ziekenhuis, locatie Nieuwegein
Longcentrum

OOSTENRIJK

WIEN
WIEN

ALARM: Advisory Lead ARDS Respirator Management
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Allgemeine Anästhesie und Intensivmedizin

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidInhaled gm-csf therapy of autoimmune pulmonary alveolar proteinosis
Institution: Information not provided - US

CANADA

Ontario
KINGSTON

Gefinancierd door een IRDiRC-lidIIH-ECC: Idiopathic Infantile Hypercalcemia - European-Canadian Consortium - CA
Queen's University
Department of Biomedical and Molecular Sciences

CANADA

Ontario
TORONTO

DUITSLAND

Bayern
GAUTING

DUITSLAND

Berlin
BERLIN

Gefinancierd door een IRDiRC-lidICON: Long-term course of juvenile idiopathic arthritis - long-term studies in health research
Deutsches Rheuma-Forschungszentrum Berlin
Forschungsbereich Epidemiologie

DUITSLAND

Berlin
BERLIN

JuMBO: Juvenile Arthritis - Methotrexate / Biologics long-term Observation
Deutsches Rheuma-Forschungszentrum Berlin
Forschungsbereich Epidemiologie

DUITSLAND

Nordrhein-Westfalen
MÜNSTER

Gefinancierd door een IRDiRC-lidICON: Long-term course of juvenile idiopathic arthritis - long-term studies in health research
Universitätsklinikum Münster
Klinik für Kinder- und Jugendmedizin - Pädiatrische Rheumatologie und Immunologie

DUITSLAND

Nordrhein-Westfalen
SANKT AUGUSTIN

FRANKRIJK

AUVERGNE-RHONE-ALPES
GRENOBLE

USIDNET: modelization of X+CGD chronic granulomatous disease and Nox2 super oxidase mutants in the PLB-985 cell line to study the NADPH oxidase activation process
CHU de Grenoble et des Alpes - Institut de biologie et de pathologie
Centre Diagnostic et Recherche sur la Granulomatose Septique Chronique

FRANKRIJK

AUVERGNE-RHONE-ALPES
LA TRONCHE

NOX NADPH oxydases in inflammatory response: physiopathological aspects, regulation mechanism and modeling
Université Grenoble Alpes (UGA) - Campus santé
GREPI : Groupe de Recherche et d'Etudes du Processus Inflammatoire

FRANKRIJK

AUVERGNE-RHONE-ALPES
LA TRONCHE

Validation of a new concept of cell therapy by transfer of proteins in enzymopathies: application to the Chronic septic granulomatosis
Université Grenoble Alpes (UGA) - Campus santé
GREPI : Groupe de Recherche et d'Etudes du Processus Inflammatoire

FRANKRIJK

CENTRE-VAL DE LOIRE
TOURS

Gefinancierd door een IRDiRC-lidAcoustic Waves and Helium/oxygen for Aerosol Treatment of Idiopathic Pulmonary Fibrosis (IPF)
Faculté de Médecine, Université de Tours François Rabelais
Équipe Inserm 3 : « Aérosolthérapie et biothérapies à visée respiratoire »

FRANKRIJK

GRAND-EST
STRASBOURG CEDEX

Gefinancierd door een IRDiRC-lidRare Invisible Disease and Schooling of Children
ESPE de Strasbourg
Equipe Apprentissages, pratiques d'enseignement et d'éducation

FRANKRIJK

ILE-DE-FRANCE
CRÉTEIL

Surfactant deficiencies in chronic lung diseases in children
Centre Hospitalier Intercommunal de Créteil
Service de pédiatrie - Hôpital de jour

FRANKRIJK

ILE-DE-FRANCE
PARIS

ERADAS and ERAFI: development and validation of the scores of activity and functional impairment in juvenile spondylitis
Hôpital Necker-Enfants Malades
Développement normal et pathologique du système immunitaire

IERLAND

County Dublin
DUBLIN

IERLAND

County Dublin
DUBLIN

Urinary sCD163 as a biomarker in crescentic glomerulonephritis
Trinity College Dublin
Trinity Translational Medicine Institute

IERLAND

County Galway
GALWAY

ITALIË

EMILIA ROMAGNA
BOLOGNA

Combined Evaluation of Pulmonary Fluids by Lung Ultrasounds and Transthoracic Electrical Bioimpedance in Preterm Infants With Respiratory Distress Syndrome
Policlinico S. Orsola-Malpighi - Area S. Orsola
Azienda Ospedaliero-Universitaria Policlinico S. Orsola-Malpighi

ITALIË

LIGURIA
GENOVA

ITALIË

LOMBARDIA
MILANO

Pathogenesis and therapy of chronic granulomatous disease by gene transfer into hematopoietic stem cells
Istituto San Raffaele Telethon per la Terapia Genica - TIGET
Unità di Ricerca Clinica

ITALIË

LOMBARDIA
MONZA

Nutritional Assessment in Idiopathic Pulmonary Fibrosis: a Pilot Study
ASST Monza - Ospedale San Gerardo
Dipartimento Cardio-Toraco-Vascolare

ITALIË

LOMBARDIA
MONZA

Cardiovascular Fibrosis in Idiopathic Pulmonary Fibrosis (CardioIPF)
ASST Monza - Ospedale San Gerardo
Dipartimento Cardio-Toraco-Vascolare

JAPAN

JAPAN
KYOTO

Gefinancierd door een IRDiRC-lidDiscovery of novel therapeutic approach for Nakajo-Nishimura syndrome and Blau syndrome
Center for iPS Cell Research and Application, Kyoto University
Department of Clinical Application

OOSTENRIJK

TIROL
INNSBRUCK

SPANJE

Andalucía
CÓRDOBA

Gefinancierd door een IRDiRC-lidIdentification of molecular heterogeneity associated with cardiovascular disease, clinical course and therapeutic response in systemic autoimmune diseases
IMIBIC - Instituto Maimónides de Investigación Biomédica de Córdoba
GC05 - Grupo de investigación en enfermedades autoinmunes inflamatorias sistémicas y crónicas del aparato locomotor

SPANJE

Asturias
OVIEDO

SPANJE

Baleares
PALMA DE MALLORCA

Gefinancierd door een IRDiRC-lidCell therapy in an experimental model of pulmonary fibrosis with telomere shortening and characterization of pulmonary MSC in IPF with telomere shortening
IdISBa - Fundació Institut d'Investigació Sanitaria Illes Balears
Grupo de investigación en Inflamación, reparación y cáncer en enfermedades respiratorias

SPANJE

Cantabria
SANTANDER

Gefinancierd door een IRDiRC-lidCharacterization of molecular bases of IgA-mediated vasculitis
IDIVAL: Instituto de Investigación Marqués de Valdecilla
Grupo de Epidemiología genética y arterioesclerosis en enfermedades inflamatorias sistémicas

SPANJE

Cataluña
BARCELONA

SPANJE

Cataluña
BARCELONA

Gefinancierd door een IRDiRC-lidStudy of mechanisms of progression to pulmonary fibrosis in patients with hypersensitivity pneumonitis
Vall d'Hebron Institut de Recerca VHIR
Grupo de investigación en neumología

SPANJE

Cataluña
L'HOSPITALET DE LLOBREGAT

Gefinancierd door een IRDiRC-lidCharacterization of telomeric pulmonary fibrosis and its biological regulation
Hospital Universitari de Bellvitge
Servicio de Neumología

SPANJE

Madrid
ALCORCÓN

Gefinancierd door een IRDiRC-lidDeciphering the role of factor-H related proteins in complement-related kidney diseases
Hospital Universitario Fundación Alcorcón
Servicio de Nefrología

SPANJE

Madrid
MADRID

Gefinancierd door een IRDiRC-lidDeciphering the role of factor-H related proteins in complement-related kidney diseases
Instituto de Investigación Hospital 12 de Octubre
Grupo de investigación en Nefrología Clínica

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidJuvenile myositis
Institution: Information not provided - US

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidNeuro-ophthalmic mechanisms of disease
Institution: Information not provided - US

USA

Washington
ADDRESS: NOT PROVIDED - US

USA

Washington
ADDRESS: NOT PROVIDED - US

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidTargeting jak3 in the treatment of autoimmune disease
Institution: Information not provided - US

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidAcid sphingomyelinase and niemann-pick disease
Institution: Information not provided - US

VERENIGD KONINKRIJK

Greater London
LONDON

ZWEDEN

Region Stockholm
STOCKHOLM

ZWITSERLAND

Suisse Alémanique
BASEL

FRANKRIJK

GRAND-EST
ILLKIRCH-GRAFFENSTADEN

Gefinancierd door een IRDiRC-lidTargeting the vitamin D receptor for the treatment of rare diseases induced by calcitriosis
Institut de génétique et de biologie moléculaire et cellulaire - IGBMC
Département Génomique fonctionnelle et cancer

IERLAND

County Dublin
DUBLIN

AVERT: Autoimmunity Relapse Prediction Using Multiple Parallel Data Sources
Trinity College Dublin
Trinity Translational Medicine Institute

ITALIË

FRIULI VENEZIA GIULIA
UDINE

Role of protein misfolding in the pathogenesis of Niemann-Pick type C disease: a possible therapeutic target
Azienda Ospedaliero-Universitaria "Santa Maria della Misericordia" di Udine
Centro di Coordinamento Regionale per le Malattie Rare

ITALIË

FRIULI VENEZIA GIULIA
UDINE

Screening of Niemann Pick type C among patients affected with psychiatric disease of unknown ethiology
Azienda Ospedaliero-Universitaria "Santa Maria della Misericordia" di Udine
Centro di Coordinamento Regionale per le Malattie Rare

ITALIË

LAZIO
ROMA

Gefinancierd door een IRDiRC-lidTargeting adenosine tone in Niemann Pick type C Disease
ISS - Istituto Superiore di Sanità
Centro Nazionale per la Ricerca e la Valutazione preclinica e clinica dei Farmaci

ITALIË

PUGLIA
BARI

Physiopathology of HCV-related Cryoglobulinemic Vasculitis: molecular, immunological and clinical analisys
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Unità di Epatologia - Sezione di Medicina Interna e Oncologia Clinica

ITALIË

TOSCANA
PISA

Study of cellular mechanisms of neuronal dysfunction in Niemann Pick type C disease and identification of neuroprotective therapies
Fondazione "Gabriele Monasterio" - Consiglio Nazionale delle Ricerche CNR
Area della Ricerca

JAPAN

JAPAN
CHIBA

Gefinancierd door een IRDiRC-lidPathological analysis and development ofan innovative therapeutic agent ofniemann-pick disease type C
Graduate School of Pharmaceutical Sciences, Chiba University
Laboratory of Chemical Pharmacology

JAPAN

JAPAN
KUMAMOTO

Gefinancierd door een IRDiRC-lidDeveloping new drugs for Niemann-Pick disease type C
Institute of Molecular Embryology and Genetics, Kumamoto University
Department of Cell Modulation

JAPAN

JAPAN
OSAKA

Gefinancierd door een IRDiRC-lidDeveloping the disease specific therapy for ANCA-associated vasculitis focused on immune regulatory factors in neutrophils
Osaka University Graduate School of Medicine
Department of Respiratory Medicine and Clinical Immunology

OOSTENRIJK

WIEN
WIEN

From AAV (ANCA-associated vasculitis) to chronic kidney disease - contribution of TenascinC
Medizinische Universität Wien
Klinisches Institut für Pathologie

OOSTENRIJK

WIEN
WIEN

Gefinancierd door een IRDiRC-lidExtracellular Vesicles (EV) as markers of active disease in AAV (ANCA-associated vasculitis) - AT
Medizinische Universität Wien
Klinisches Institut für Pathologie

PORTUGAL

NORTE
PORTO

The sorting and trafficking of lysosomal proteins through M6P independent pathways: molecular, biochemical and functional studies
Instituto Nacional de Saúde Dr. Ricardo Jorge - Porto
Unidade de Investigação & Desenvolvimento; Departamento de Genética

SPANJE

Andalucía
GRANADA

Gefinancierd door een IRDiRC-lidUrinary biomarkers for the non-invasive diagnosis of kidney disease in systemic autoimmune diseases
GENYO - Genómica e Investigación Oncológica
Grupo de Genética de enfermedades complejas

SPANJE

Cataluña
BARCELONA

Corrective therapy of splicing by antisense oligonucleotides for Niemann-Pick disease type C: pre-clinical study in a murine model
Universitat de Barcelona. Facultat de Biologia
Departamento de genética molecular humana

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidTherapeutics for rare and neglected diseases - science
Institution: Information not provided - US

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidDevelopment of neurosteroids for lysosomal storage disorders
Institution: Information not provided - US

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidGenetic analysis of complex inflammatory disorders
Institution: Information not provided - US

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidGenetic and genomic analysis of niemann pick type c1 disease
Institution: Information not provided - US

USA

Washington
ADDRESS: NOT PROVIDED - US

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidNovel regulators of inflammatory arthritis and bone erosion
Institution: Information not provided - US

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidPathogenesis of behcet's disease and still's disease
Institution: Information not provided - US

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidClinical investigations of niemann-pick disease; type c
Institution: Information not provided - US

USA

Washington
ADDRESS: NOT PROVIDED - US

Gefinancierd door een IRDiRC-lidInborn errors of cholesterol synthesis
Institution: Information not provided - US

VERENIGD KONINKRIJK

Glasgow
GLASGOW

Gefinancierd door een IRDiRC-lidHarnessing the power of integrated data to investigate environmental exposures on ANCA vasculitis risk , an unbiased approach -GB
Institute of Infection, Immunity and Inflammation, University of Glasgow
Institute of Infection, Immunity and Inflammation

FRANKRIJK

ILE-DE-FRANCE
PARIS

Model contribution in the microeconomic assessment of therapeutic strategies in Wegener granulomatosis
CHU Paris Centre - Hôpital Cochin, Site Cochin
Service de Santé publique : Gestion des risques et qualité

USA

Washington
ADDRESS: NOT PROVIDED - US

USA

Washington
ADDRESS: NOT PROVIDED - US

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