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182 Resultado(s)

Ordenados por

Financiado por um membro do IRDiRC = Membro de uma ERN =

Projetos de investigação

ALEMANHA

Baden-Württemberg
HEIDELBERG

Financiado por um membro do IRDiRCERA-NET TRANSCAN: BRCAddict - BRCAness as a therapeutic target for solid high-risk childhood tumors
Deutsches Krebsforschungszentrum
KITZ - Hopp-Kindertumorzentrum Heidelberg

AUSTRIA

WIEN
WIEN

Christian Doppler Laboratory for Next Generation CAR-T Cells
St. Anna Kinderkrebsforschung
Children's Cancer Research Institute

BELGICA

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

CANADA

Ontario
TORONTO

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

FRANCA

ILE-DE-FRANCE
ORSAY

DCD-CANC-CHILD: design of drug carrier and delivery control for cancer therapy of children
Université Paris-Sud
Institut de Chimie Moléculaire et des Matériaux d'Orsay

ITALIA

VENETO
PADOVA

Financiado por um membro do IRDiRCModulating BMP axis to prevent muscle loss, dismantling of NMJ and denervation in cancer cachexia
Venetian Institute of Molecular Medicine
Fondazione per la ricerca Biomedica avanzata ONLUS

SUICA

Suisse Alémanique
WINTERTHUR

ALEMANHA

Nordrhein-Westfalen
BONN

ALEMANHA

Nordrhein-Westfalen
MÜNSTER

Functional role of genes and pathways in histone H3 mutated gliomas
Institut für Neuropathologie der Medizinischen Fakultät Münster
Institut für Neuropathologie

ALEMANHA

Rheinland-Pfalz
MAINZ

BLU-Men: Psychological stress and quality of life in patients with untreated MENingeomas
Universitätsmedizin Mainz
Neurochirurgische Klinik und Poliklinik

ALEMANHA

Rheinland-Pfalz
MAINZ

GLIOPT -Glioma patients in ambulatory care - Optimization of psychosocial care in neurooncological patients
Universitätsmedizin Mainz
Universitäres Centrum für Tumorerkrankungen (UCT) Mainz

AUSTRIA

WIEN
ADDRESS: NOT PROVIDED - AT

Financiado por um membro do IRDiRCGliMR2.0: Glioma MR Imaging 2.0 - AT
Institution: Information not provided - AT

AUSTRIA

WIEN
WIEN

Improved Visualization and Resection of Brain Tumors with Quantitative Fluorescence and Optical Coherence Tomography
Allgemeines Krankenhaus der Stadt Wien
Universitätsklinik für Neurochirurgie

AUSTRIA

WIEN
WIEN

Financiado por um membro do IRDiRCITCC-P4: Pediatric Preclinical Proof of Concept Platform - AT
Medizinische Universität Wien
Institut für Krebsforschung

AUSTRIA

WIEN
WIEN

Magnetic Resonance Fingerprinting of Patients with Gliomas
Medizinische Universität Wien
Exzellenzzentrum für Hochfeld-MR

ESTADOS UNIDOS

South Dakota
SIOUX FALLS

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCEstablishing the genomic landscape of human atypical meningiomas
Institution: Information not provided - US

IRLANDA

County Dublin
DUBLIN

PORTUGAL

SUL
LISBOA

Papel da proteína cinase WNK2 como gene supressor de gliomas malignos
Instituto Nacional de Saúde Dr. Ricardo Jorge - Lisboa
Unidade de Investigação e Desenvolvimento

SUECIA

Region Uppsala
UPPSALA

Molecular mechanisms of the origine of glioma development
Uppsala Universitet
Department of Immunology, Genetics and Pathology

SUICA

Suisse Alémanique
BERN

Metabolic Characterization of Space Occupying Lesions of the Brain Using in Vivo MR- (Spectroscopic) Imaging at 3 Tesla and 7 Tesla
University Hospital Inselspital
Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie

SUICA

Suisse Alémanique
ZÜRICH

To reveal and target molecular interactions causative for pro-invasive signaling in malignant brain tumors
Universitäts-Kinderspital Zürich
Abteilung Onkologie - Experimental Infectious Diseases and Cancer Research

ALEMANHA

Baden-Württemberg
HEIDELBERG

INFORM-Registry: INdividualized Therapy FOr Relapsed Malignancies in Childhood
Deutsches Krebsforschungszentrum
Klinische Kooperationseinheit Pädiatrische Onkologie

ALEMANHA

Hamburg
HAMBURG

International HIT-MED Registry (I-HIT-MED) for Children, Adolescents, and Adults With Medulloblastoma, Ependymoma, Pineoblastoma, CNS-primitive Neuroectodermal Tumour
UKE - Universitätsklinikum Hamburg-Eppendorf
Klinik und Poliklinik für Pädiatrische Hämatologie und Onkologie

ALEMANHA

Nordrhein-Westfalen
MÜNSTER

Clinical and molecular features predicting outcome in children with atypical teratoid/rhabdoid tumour (AT/RT)
Institut für Neuropathologie der Medizinischen Fakultät Münster
Institut für Neuropathologie

AUSTRIA

WIEN
WIEN

Financiado por um membro do IRDiRCBRCAddict: Harnessing BRCAness as a therapeutic target in high-risk pediatric solid tumors - AT
Allgemeines Krankenhaus der Stadt Wien
Universitätsklinik für Kinder- und Jugendheilkunde

CANADA

Ontario
TORONTO

Financiado por um membro do IRDiRCMolecular Determinants of Li-Fraumeni Syndrome Associated Cancers
Hospital for Sick Children, Research Institute

CANADA

Québec
MONTRÉAL

Financiado por um membro do IRDiRCIdentification and characterization of genes involved in the genesis and progression of pediatric astrocytomas
Montreal Children's Hospital Research Institute - McGill University
Department of Pediatrics / Département de pédiatrie

CANADA

Québec
MONTRÉAL

Financiado por um membro do IRDiRCRole of chromatin remodeling in the genesis of pediatric and young adult astrocytomes
Montreal Children's Hospital Research Institute - McGill University
Department of Pediatrics / Département de pédiatrie

CANADA

Québec
MONTRÉAL

Financiado por um membro do IRDiRCThe ICHANGE (International CHildhood Astrocytomas iNtegrated Genomics and Epigenomics) Consortium
Montreal Children's Hospital Research Institute - McGill University
Department of Pediatrics / Département de pédiatrie

ESTADOS UNIDOS

South Dakota
SIOUX FALLS

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCPrecision medicine for pediatric low-grade gliomas
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCFunctional genomic analysis of neural crest development
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCMir-155 and runx function in neurofibroma tumorigenesis and therapy
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCRegulation of medulloblastoma metastasis by emp1
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCRegulation of shh signaling by cellular energetics
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCTargeting mechanisms of medulloblastoma formation
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCTargeting wee1 in myc driven medulloblasoma
Institution: Information not provided - US

FRANCA

ILE-DE-FRANCE
VILLEJUIF

Financiado por um membro do IRDiRCBRCAddict: Harnessing BRCAness as a therapeutic target in high-risk pediatric solid tumors - FR (Partener 1)
CLCC Institut Gustave Roussy
Département de Cancérologie de l'enfant et de l'adolescent

REINO UNIDO

Greater London
LONDON

Use of DTT to Define Facial Nerve Position in Vestibular Schwannomas
King's College Hospital
King's College Hospital NHS Foundation Trust HQ

SUECIA

Region Stockholm
STOCKHOLM

Novel targeted therapy for childhood cancer with emphasis on Wip-1 in medulloblastoma and neuroblastoma
Karolinska Institutet - Solna
Department of Women's and Children's Health

SUECIA

Region Stockholm
STOCKHOLM

INTENT: innovative approach for treatment of neuroblastoma and medulloblastoma
Karolinska Institutet - Solna
Department of microbiology, tumor and cell biology

ALEMANHA

Nordrhein-Westfalen
KÖLN

Molecular basis for tumor suppression and spontanous regression in neuroblastoma
Universitätsklinikum Köln
Pädiatrische Onkologie und Hämatologie

ALEMANHA

Sachsen
LEIPZIG

NB-MolBiol-2020: Study on the clinical significance of cell biological parameters in diagnostics, prognosis and therapy for neuroblastoma patients
Zentrum für Frauen- und Kindermedizin am Universitätsklinikum Leipzig
Abteilung für Pädiatrische Onkologie, Hämatologie und Hämostaseologie

AUSTRIA

SALZBURG
SALZBURG

Adjuvant multimodal metabolic therapy of neuroblastoma
Universitätsklinikum der Paracelsus Medizinischen Privatuniversität
Universitätsklinik für Kinder- und Jugendheilkunde

AUSTRIA

WIEN
WIEN

Identifying immunological characteristics associated with disease progression in low grade glioma
Allgemeines Krankenhaus der Stadt Wien
Universitätsklinik für Neurochirurgie

AUSTRIA

WIEN
WIEN

Quantitative measurement of 5-ALA fluorescence for improved detection of low-grade gliomas
Allgemeines Krankenhaus der Stadt Wien
Universitätsklinik für Neurochirurgie

AUSTRIA

WIEN
WIEN

Pharmacokinetics of different antibiotics in cerebrospinal fluid in children with malignant brain tumors - a pilot study
Allgemeines Krankenhaus der Stadt Wien
Universitätsklinik für klinische Pharmakologie

AUSTRIA

WIEN
WIEN

AUSTRIA

WIEN
WIEN

Ultra-high-risk pediatric cancer - combinatorial drivers and therapeutic targets for precision medicine
St. Anna Kinderkrebsforschung
Children's Cancer Research Institute

COREIA DO SUL

KOREA, REPUBLIC OF
SEOUL

ESPANHA

Cataluña
BARCELONA

Targeting kinesins as new therapeutic approach for high-risk neuroblastoma patients
Vall d'Hebron Institut de Recerca VHIR
Grupo de investigación traslacional en cáncer en la infancia y la adolescencia

ESPANHA

Madrid
MADRID

Financiado por um membro do IRDiRCTherapy for treatment of neuroblastoma based on the use of the CRISPR/Cas9 gene editing system
Centro Nacional de Investigaciones Oncológicas (CNIO)
Unidad de Citogenética Molecular

ESPANHA

Madrid
MADRID

Financiado por um membro do IRDiRCCombination of nanomedicine and immunotherapy for the treatment of neuroblastoma
Hospital Infantil Universitario Niño Jesús
Servicio de Oncohematología

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCTargeting olig2 co-regulators for malignant glioma therapy
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCDrug repurposing screening for rare and neglected diseases
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCDeconstruct tumor microenvironment in medulloblastoma
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCTargeting bet-bromodomains in neuroblastoma
Institution: Information not provided - US

FINLANDIA

Finland
HELSINKI

Financiado por um membro do IRDiRCLessons learned from the embryo to help understand neuroblastoma formation
University of Helsinki
Department of Biochemistry and Developmental Biology

FRANCA

AUVERGNE-RHONE-ALPES
ADDRESS: NOT PROVIDED - FR

FRANCA

AUVERGNE-RHONE-ALPES
ADDRESS: NOT PROVIDED - FR

FRANCA

AUVERGNE-RHONE-ALPES
LYON

SUICA

Suisse Romande
LAUSANNE

SUICA

Suisse Romande
LAUSANNE

ALEMANHA

Nordrhein-Westfalen
DÜSSELDORF

Targeting HOTAIRM1 in Glioblastoma Multiforme
Universitätsklinikum Düsseldorf
Hirntumor-Referenzzentrum der DGNN

AUSTRIA

WIEN
ADDRESS: NOT PROVIDED - AT

AUSTRIA

WIEN
ADDRESS: NOT PROVIDED - AT

AUSTRIA

WIEN
WIEN

TERT promoter mutations and cancer aggressiveness
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Onkologie

AUSTRIA

WIEN
WIEN

CDK 4/6 inhibitors as a new therapeutic strategy in pediatric brain tumors
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Neonatologie, Pädiatrische Intensivmedizin und Neuropädiatrie

AUSTRIA

WIEN
WIEN

Fibroblast Growth Factor Receptor 4 in Glioblastoma
Medizinische Universität Wien
Institut für Krebsforschung

ESPANHA

Baleares
PALMA DE MALLORCA

Financiado por um membro do IRDiRCIntegrative characterization of molecular biomarkers for the precision diagnosis and treatment of patients with glioblastoma
IdISBa - Fundació Institut d'Investigació Sanitaria Illes Balears
BIOCANCER: Grupo de Biología Celular del Cáncer

ESPANHA

Castilla - La Mancha
ALBACETE

Financiado por um membro do IRDiRCNanomedicine for glioblastoma therapy
Universidad de Castilla-La Mancha. Campus de Albacete. Facultad de Medicina
Unidad Neurodeath

ESPANHA

Cataluña
BADALONA

ESPANHA

Comunidad Valenciana
VALENCIA

Financiado por um membro do IRDiRCIntegrative personal omics profiles in glioblastoma recurrence and therapy resistance
IIS La Fe - Instituto de Investigación Sanitaria La Fe
GIBI230: Grupo de Investigación Biomédica en Imagen

ESPANHA

Galicia
SANTIAGO DE COMPOSTELA

Financiado por um membro do IRDiRCSilk-fibroin interventional nano-trap for the treatment of glioblastoma
Universidad de Santiago de Compostela. Facultad de Farmacia
I+D Farma

ESPANHA

Madrid
MADRID

Financiado por um membro do IRDiRCNanomedicine for glioblastoma therapy
Hospital Universitario Ramón y Cajal
Servicio de Oncología Médica

ESPANHA

Navarra
PAMPLONA

Financiado por um membro do IRDiRCRole of RNU6 isolated from circulating exosomes as a potential diagnostic and follow-up biomarker for patients with glioblastoma
CIMA - Centro de Investigación Médica Aplicada
Grupo de Terapias avanzadas para tumores sólidos pediátricos

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCImmunobiology of malignant glioma
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCComparative mammalian genomics
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCGlioblastoma stem cell-derived pericytes and cancer invasion
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCModeling malignant progression in glioma
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCNeuronal activity-regulated mechanisms of glioma growth
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCNeuroimmunology of malignant brain tumors: innate mechanisms
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCRole of glud2 as a metabolic driver of gliomas with idh1 mutations
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCSystemic gene therapy for glioblastoma
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCThe mayo gbm xenograft national resource
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCTargeting epha2 in glioblastoma
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCSelective targeting of glioma stem cells through sema3c/plexind1
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCUbiquitination and deubiquitination of c-myc in glioblastoma
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCChromatin modifications in gbm-propagating cells
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCCellular plasticity and equilibrium in gbm progression
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCExploiting mtap deletion for gbm therapeutics
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCMechanisms of riok2 function in glioblastoma
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCThe role of tumor associated macrophages in glioblastoma
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCTargeting kif11 to treat glioblastoma invasion and proliferation
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCPhysical-chemical aspects of cell and tissue excitability
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCTherapeutically relevant targets of twist1 dimers in glioma
Institution: Information not provided - US

FINLANDIA

Finland
KUOPIO

New therapeutic treatments for malignant glioma
Itä-Suomen yliopisto
A.I.Virtanen -Instituutti

FINLANDIA

Finland
KUOPIO

Financiado por um membro do IRDiRCLAT1-targeted prodrugs for improved drug delivery to invasive glioma cells
University of Eastern Finland
Faculty of Health Sciences

FRANCA

AUVERGNE-RHONE-ALPES
ADDRESS: NOT PROVIDED - FR

FRANCA

AUVERGNE-RHONE-ALPES
ADDRESS: NOT PROVIDED - FR

FRANCA

AUVERGNE-RHONE-ALPES
ILLKIRCH

Systems biology of integrin inhibition-induced apoptosis for novel glioblastoma treatment
LBP - Laboratory of Bioimaging and Pathologies
Tumoral signaling and therapeutic targets

FRANCA

AUVERGNE-RHONE-ALPES
LYON

Identification of networks of alternative splicing events that coordinate cell heterogeneity and resistance to glioblastoma therapies
Centre de Recherche en Cancérologie Lyon-Est
Diversité du transcriptome des cellules souches

FRANCA

BRETAGNE
RENNES

Tumor activity of IRE1 and remodeling of the immune microenvironment of glioblastomas
Centre de Lutte Contre le Cancer Eugène Marquis
Oncogenesis, Stress & Signaling Laboratory

FRANCA

NORMANDIE
CAEN

Radiosensitization and reoxygenation of tumors via zeolites containing gadolinium: an original theranostic approach for glioblastomas
GIP CYCERON
Equipe CERVOxy | Hypoxie, physiopathologies cérébrovasculaire et tumorale

FRANCA

PROVENCE-ALPES-COTE D'AZUR
MARSEILLE

Development of a new drug therapy for glioblastoma
Parc scientifique et technologiques de Luminy
Pharmaxon

PORTUGAL

CENTRO
BRAGA

REINO UNIDO

Cambridgeshire
CAMBRIDGE

SUICA

Suisse Romande
EPALINGES

Epigenetic landscape of gliomas and their implications for tumor biology and treatment of cancer
Université de Lausanne UNIL
Laboratoire de biologie et génétique des tumeurs cérébrales (LBGT)

Projetos de investigação multicêntricos