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91 Resultado(s)

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Financiado por um membro do IRDiRC = Membro de uma ERN =

Projetos de investigação

CANADA

Ontario
TORONTO

ITALIA

LOMBARDIA
MILANO

RBDD: Rare Bleeding Disorders Database network (coordination)
Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico
Laboratorio di Patologie Molecolari Applicate alla Clinica

ALEMANHA

Mecklenburg-Vorpommern
GREIFSWALD

Mutational spectra and clinical manifestation in patients with congenital haemophilia
Institut für Humangenetik der Universitätsmedizin Greifswald
Institut für Humangenetik

FRANCA

ILE-DE-FRANCE
LE KREMLIN-BICÊTRE

Diagnosis and treatment of acquired hemostatic disorders due to auto-antibodies
CHU Paris-Sud - Hôpital de Bicêtre
Service d'Hématologie

FRANCA

PROVENCE-ALPES-COTE D'AZUR
MARSEILLE

JAPAO

JAPAN
FUKUOKA

SUECIA

Region Skåne
LUND

Bacterial virulence factors, innate immunity and prothrombotic mechanisms in renal disease
Skånes Universitetssjukhus
Department of Clinical Sciences, Division of Pediatrics

SUICA

Suisse Alémanique
BERN

Thrombotic thrombocytopenic purpura - role of ADAMTS13 and long-term outcome
University Hospital Inselspital
Department of Hematology and Central Hematology Laboratory

ALEMANHA

Baden-Württemberg
TÜBINGEN

AWISPECS: The role of acquired von Willebrand syndrome in cardiosurgical interventions in infancy
Universitätsklinik für Kinder- und Jugendmedizin Tübingen
Abteilung für Kinderkardiologie, Pulmologie, Intensivmedizin

ALEMANHA

Bayern
MÜNCHEN

Establishment of surface plasmon resonance (SPR) tests for improved diagnostics of autoimmune diseases
Klinikum rechts der Isar der Technischen Universität München
Arbeitsgruppe Biosensorik

ALEMANHA

Sachsen-Anhalt
HALLE (SAALE)

AUSTRIA

STEIERMARK
GRAZ

CRISPR/Cas9 genome engineering to dissect MPN (myeloproliferative neoplasm) pathogenesis
Medizinische Universität Graz
Klinische Abteilung für Hämatologie

AUSTRIA

WIEN
WIEN

Financiado por um membro do IRDiRCProspective, Non-interventional Study to Evaluate the Safety and Effectiveness of Obizur in Real-life Practice - AT
Allgemeines Krankenhaus der Stadt Wien
Klinische Abteilung für Hämatologie und Hämostaseologie

ESPANHA

Andalucía
CÓRDOBA

Financiado por um membro do IRDiRCIdentification of molecular heterogeneity associated with cardiovascular disease, clinical course and therapeutic response in systemic autoimmune diseases
IMIBIC - Instituto Maimónides de Investigación Biomédica de Córdoba
GC05 - Grupo de investigación en enfermedades autoinmunes inflamatorias sistémicas y crónicas del aparato locomotor

ESPANHA

Murcia
EL PALMAR

Financiado por um membro do IRDiRCIdentification of new factors involved in the onset, progression, and complications of Philadelphia-negative chronic myeloproliferative neoplasia
IMIB - Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca
Grupo de Hematología y Oncología Médica Clínico-Experimental

FRANCA

ILE-DE-FRANCE
LE KREMLIN-BICÊTRE

FRANCA

ILE-DE-FRANCE
PARIS

Implementation of non-invasive prenatal diagnosis of rare and severe monogenic diseases
CHU Paris Centre - Hôpital Cochin, Site Cochin
Service de génétique et biologie moléculaires

IRLANDA

County Dublin
DUBLIN

Financiado por um membro do IRDiRCIrish Personalised Approach to the Treatment of Haemophilia (iPATH)
Children's Health Ireland @ Crumlin
Haematology Department

IRLANDA

County Dublin
DUBLIN

The Low Von Willebrand factor Ireland Cohort of Kids (LoVIC-K) study
Royal College of Surgeons of Ireland
Molecular and Cellular Theraputics

IRLANDA

County Dublin
DUBLIN

IRLANDA

County Dublin
DUBLIN

Financiado por um membro do IRDiRCIrish Personalised Approach to the Treatment of Haemophilia (iPATH)
St James's Hospital
National Coagulation Centre

ITALIA

EMILIA ROMAGNA
MELDOLA

Integrated Multiomics and Multilevel Characterization of Haematological Disorders and Malignancies
IRST - Istituto Scientifico Romagnolo per lo studio e la cura dei Tumori
IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori

ITALIA

LOMBARDIA
MILANO

Financiado por um membro do IRDiRCDevelopment of lentiviral vectors for liver gene transfer and application to hemophilia gene therapy
Istituto San Raffaele Telethon per la Terapia Genica - TIGET
Istituto San Raffaele Telethon per la Terapia Genica

JAPAO

JAPAN
MIYAGI

Financiado por um membro do IRDiRCDevelopment of a predictive method for bleeding complication associated with intractable cardiovascular diseases with high shear-stress
Institute of Development and Aging and Cancer,Tohoku University
Department of Molecular and Cellular Biology

JAPAO

JAPAN
MIYAGI

Financiado por um membro do IRDiRCDevelopment of management for acquired von Wilebrand syndrome complicated with mechanical circulatory support
Tohoku University Graduate School of Medicine
Department of Cardiovascular Surgery

REINO UNIDO

Cambridgeshire
CAMBRIDGE

REINO UNIDO

Greater London
LONDON

Liver Disease in Pregnancy
King's College London
King's College London Headquarters

SUICA

Suisse Romande
GENÈVE

Molecular mechanisms and clinical consequences of variable fibrinogen levels
Centre Médical Universitaire - CMU
Département de médecine génétique et développement

ALEMANHA

Baden-Württemberg
FREIBURG

Financiado por um membro do IRDiRCGAIN: German network for research and therapy optimization of patients with multi-organ autoimmune diseases
CCI am Universitätsklinikum Freiburg
Centrum für Chronische Immundefizienz

ALEMANHA

Niedersachsen
HANNOVER

Financiado por um membro do IRDiRCGAIN: German network for research and therapy optimization of patients with multi-organ autoimmune diseases
Medizinische Hochschule Hannover
Klinik für Rheumatologie und Immunologie

ALEMANHA

Nordrhein-Westfalen
BONN

ALEMANHA

Nordrhein-Westfalen
BONN

Enzymological and structural biology investigation on the function of the vitamin K cycle
Universitätsklinikum Bonn (AöR)
Institut für Experimentelle Hämatologie und Transfusionsmedizin

ALEMANHA

Schleswig-Holstein
KIEL

Financiado por um membro do IRDiRCGAIN: German network for research and therapy optimization of patients with multi-organ autoimmune diseases
Universitätsklinikum Schleswig-Holstein - Campus Kiel
Klinik für Innere Medizin I

AUSTRIA

WIEN
ADDRESS: NOT PROVIDED - AT

Financiado por um membro do IRDiRCAHEAD: ADVATE Hemophilia A Outcome Database - AT
Institution: Information not provided - AT

CANADA

Ontario
KINGSTON

Financiado por um membro do IRDiRCStudy of the factor VIII life cycle and its implications for factor VIII immunogenicity
Queen's University
Department of Pathology and Molecular Medicine

ESPANHA

Castilla - León
BURGOS

ESPANHA

Comunidad Valenciana
VALENCIA

Personalized Prophylactic Treatment With Advate® in Severe or Moderate Haemophilia A Patients
Hospital Universitario y Politécnico La Fe
Servicio de Farmacia, Área Clínica del Medicamento

ESPANHA

Murcia
EL PALMAR

Financiado por um membro do IRDiRCMolecular pathology of antithrombin deficiency: development of new diagnostic methods and clinical implications
IMIB - Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca
Grupo de Hematología y Oncología Médica Clínico-Experimental

FRANCA

GRAND-EST
ILLKIRCH-GRAFFENSTADEN

Search for Scott syndrom causative mutation(s)
Faculté de Pharmacie de Strasbourg
Laboratoire de Bioimagerie et Pathologies - LBP

FRANCA

ILE-DE-FRANCE
PARIS

Constitutive hematologic diseases: clinical and therapeutic research, molecular biology
CHU Paris-GH St-Louis Lariboisière F.Widal - Hôpital Saint-Louis
Service d'hématologie pédiatrique

ITALIA

UMBRIA
PERUGIA

Financiado por um membro do IRDiRCDissecting dendritic cell subsets as key to installing tolerance to FVIII in hemophilia A
Università degli Studi di Perugia
Dipartimento di Medicina Sperimentale

JAPAO

JAPAN
TOKYO

Financiado por um membro do IRDiRCEstablishment of diagnostic system, registry and sample banking in congenital thrombocytopenia
National Center for Child Health and Development
Research Institute

REINO UNIDO

Greater Manchester
ADDRESS: NOT PROVIDED - UK

Financiado por um membro do IRDiRCADVATE Hemophilia A Outcome Database (AHEAD) - UK
Institution: Information not provided - UK

AUSTRIA

WIEN
ADDRESS: NOT PROVIDED - AT

CANADA

Ontario
TORONTO

ESPANHA

Madrid
MADRID

Financiado por um membro do IRDiRCStudy of the procoagulant effect of emicizumab and of its combination with factor concentrates for the treatment of bleeds in patients with severe haemophilia A
IdiPAZ - Instituto de Investigación Sanitaria del Hospital Universitario La Paz
Grupo de Coagulopatías y alteraciones de la hemostasia

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCCell biology of metabolic disorders
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

FRANCA

AUVERGNE-RHONE-ALPES
PRAGUE

Financiado por um membro do IRDiRCRole on Nonmuscle Myosin II in membrane trafficking and organ function
Faculty of Medicine and University Hospital Motol
Department of Pediatrics

FRANCA

GRAND-EST
STRASBOURG

Bernard-Soulier Syndrome and MYH9 associated diseases: study of blood platelets anomalies and of the thrombopoïesis, correction by genetic therapy
Établissement Français du Sang - Grand Est
UR U311 - Biologie et pharmacologie de l'hémostase et de la thrombose

ISRAEL

ISRAEL
ADDRESS: NOT PROVIDED - IL

Financiado por um membro do IRDiRCZebrafish as a model system for GNE Myopathy
Institution: Information not provided - IL

REINO UNIDO

Tyne & Wear
NEWCASTLE UPON TYNE

ESPANHA

País Vasco
BARAKALDO

Financiado por um membro do IRDiRCIn vitro modeling of primary immunodeficiencies with defects in NK cells
Instituto de Investigación sanitaria Biocruces Bizkaia
Grupo de investigación en terapia celular, células madre y tejidos

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCGene therapy approaches for primary immunodeficiencies
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCMolecular and clinical studies of primary immunodeficiencies
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCClinical research of oral connective tissue program
Institution: Information not provided - US

ESTADOS UNIDOS

Washington
ADDRESS: NOT PROVIDED - US

Financiado por um membro do IRDiRCProtein trafficking in the endosomal-lysosomal system
Institution: Information not provided - US

FRANCA

GRAND-EST
STRASBOURG

Characterisation of mutations responsible for Bernard-Soulier syndrome (GP1BA, BP1BB and GP9 genes)
Établissement Français du Sang - Grand Est
UR U311 - Biologie et pharmacologie de l'hémostase et de la thrombose

ITALIA

LOMBARDIA
MILANO

Production of vectors for gene therapy (Wiskott-Aldrich Syndrome and Metachromatic Leukodystrophy)
Istituto San Raffaele Telethon per la Terapia Genica - TIGET
Istituto San Raffaele Telethon per la Terapia Genica

ITALIA

LOMBARDIA
MILANO

Financiado por um membro do IRDiRCWiskott-Aldrich syndrome: characterization of immune system defects and gene therapy preclinical studies
Istituto San Raffaele Telethon per la Terapia Genica - TIGET
Unità di Ricerca Clinica

REINO UNIDO

Devon
EXETER

Financiado por um membro do IRDiRCThe Fundamentals of Phagocytosis: Integrating Theoretical Models and Experiments
University of Exeter, Physics building
Department of Physics and Astronomy

SUICA

Suisse Romande
LAUSANNE

Role of the Wiskott-Aldrich Syndrome Protein (WASp) in the Differentiation and Regulation of the Immune System
Centre Hospitalier Universitaire Vaudois CHUV
Service d'immunologie et allergie

ITALIA

LAZIO
ROMA

Financiado por um membro do IRDiRCRole of Dystrophin-associated protein complex (DPC) in intracellular signaling and trafficking pathways
ISS - Istituto Superiore di Sanità
Centro Nazionale Malattie Rare

REINO UNIDO

Cambridgeshire
CAMBRIDGE

Projetos de investigação multicêntricos