Orphanet: Renin angiotensin aldosterone system blocker induced angioedema

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Renin-angiotensin-aldosterone system-blocker-induced angioedema

Disease definition

Renin-angiotensin-aldosterone system (RAAS)-blocker induced angioedema (RAE) is a type of acquired angioedema (AAE, see this term) characterized by acute edema in subcutaneous tissues, viscera and/or the upper airway.


Classification level: Disorder
  • Synonym(s):
    • ACE inhibitor-related acquired angioedema
    • ACEI-related acquired angioedema
    • Acquired angioedema with normal C1 inhibitor
    • Acquired angioedema with normal C1INH
    • RAAS-blocker-induced angioedema
    • RAAS-blocker-induced angioneurotic edema
    • RAE
    • Renin-angiotensin-aldosterone system-blocker-induced angioneurotic edema
  • Prevalence: Unknown
  • Inheritance: Multigenic/multifactorial or Not applicable 
  • Age of onset: Adult
  • ICD-10: T78.3
  • OMIM: 300909
  • UMLS: -
  • MeSH: -
  • GARD: -
  • MedDRA: -
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