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Hepatitis delta

Disease definition

Hepatitis delta is a rare hepatic disease characterized by variable degrees of acute hepatitis resulting from infection with the hepatitis delta virus. Occasionally it may present a benign course, but most frequently it manifests with severe liver disease that may include fulminant liver failure, hepatic decompensation and rapid progression to cirrhosis. All patients present concomitant hepatitis B virus infection and an increased risk of developing hepatocellular carcinoma has been reported.


Classification level: Disorder
  • Synonym(s):
    • HDV
    • Hepatitis D virus
  • Prevalence: 1-5 / 10 000
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: B17.0
  • OMIM: -
  • UMLS: C0011226
  • MeSH: -
  • GARD: -
  • MedDRA: -
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