x

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.

Attention

Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Wild type ATTR amyloidosis

Disease definition

A rare systemic amyloidosis characterized by combination of various symptoms, depending on the organ involved. Common clinical features are cardiac failure, cardiac conduction anomalies or arrhythmia, renal dysfunction, carpal tunnel syndrome and spinal canal stenosis. Histology reveals fibrillary amyloid deposition of wild type transthyretin mostly in the kidneys, heart, gastrointestinal tract, skin and tenosynovial tissue.

ORPHA:330001

  • Synonym(s):
    • ATTRwt amyloidosis
    • ATTRwt-related amyloidosis
    • SSA
    • Senile systemic amyloidosis
    • Wild type ATTR-related amyloidosis
  • Prevalence: 1-5 / 10 000
  • Inheritance: Not applicable 
  • Age of onset: Adult
  • ICD-10: E85.8
  • OMIM: -
  • UMLS: -
  • MeSH: -
  • GARD: -
  • MedDRA: -

Detailed information

Article for general public

The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.