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Postpoliomyelitis syndrome

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Disease definition

Postpoliomyelitis syndrome (PPS) is a neurologic disorder characterized by the development of new neuromuscular symptoms such as progressive muscular weakness or abnormal muscle fatigability occurring in survivors of the acute paralytic form of poliomyelitis (see this term), 15-40 years after recovery from the disease, and that is unexplained by other medical causes. Other manifestations that can occur gradually include generalized fatigue, muscle atrophy, muscle and joint pain, intolerance to cold, and difficulties sleeping, swallowing or breathing.


Classification level: Disorder

  • Postpolio sequelae
  • Postpolio syndrome
  • Postpoliomyelitic syndrome
  • Postpoliomyelitis sequelae

Prevalence: Unknown

Inheritance: Not applicable

Age of onset: Adolescent, Adult, Elderly

ICD-10: G14

ICD-11: 8B62

UMLS: C0080040

MeSH: D016262

GARD: 4454

A summary on this disease is available in Français (2014) Español (2014) Deutsch (2004) Italiano (2014) Nederlands (2014) Polski (2014.pdf)
Detailed information
General public
Article for general public
Patient-Centered Outcome Measures (PCOMs)
English (2023) - PROQOLIDTM
Clinical practice guidelines

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