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Eosinophilic fasciitis

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Disease definition

A rare idiopathic inflammatory myopathy that is characterized by inflammation and thickening of the fascia, usually associated with peripheral eosinophilia. It presents during adulthood with symmetrical and painful swelling of mainly the extremities that progressively become indurated. Fatigue, disabling cutaneous fibrosis, myositis and arthritis may also be observed.


Classification level: Disorder

  • Diffuse fasciitis with eosinophilia
  • Shulman syndrome

Prevalence: Unknown

Inheritance: Unknown

Age of onset: Adult

ICD-10: M35.4

ICD-11: 4A43.4

OMIM: 226350

UMLS: C0264005

MeSH: C562487

GARD: 6351

MedDRA: 10014954

A summary on this disease is available in Français (2013) Español (2013) Deutsch (2013) Italiano (2013) Nederlands (2013) Polski (2013.pdf) Русский (2013.pdf) 日本語 (2019.pdf)
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