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A rare systemic autoimmune disease characterized by hypercoagulability with vascular thrombosis and, in women, pregnancy morbidity (miscarriages, severe pre-eclampsia, placental insufficiency) in the presence of serum antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies, and anti-beta2-glycoprotein 1 antibodies.
Classification level: Disorder
- Antiphospholipid antibody syndrome
- Classic APLS
- Classic antiphospholipid syndrome
- Hughes syndrome
Age of onset:
Article for general public
Clinical practice guidelines
: produced/endorsed by ERN(s)
: produced/endorsed by FSMR(s)
Further information on this disease
Patient-centred resources for this disease
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